Scientists Develop a Harmless Multi-Tasking Reovirus
...ted how cells taken from a colorectal cancer liver metastases were more susceptible to death many weeks after treatment with reovirus, and long after the virus had cleared the patient's system. These cells, when cultured in the laboratory, also appeared to be vulnerable to re-infection with reovirus. Moreover, ...More Americans Suffer from Vertebral Compression Fractures
... and unresponsive to conservative therapy ?Painful metastases and multiple myelomas ?Painful vertebral hemangiomas (benign, malformed vascular tumors composed of newly formed blood vessels) ?Vertebral osteonecrosis (a condition resulting from poor blood supply to an area of bone, which causes bone death) ?Reinf...Inflammation May Play Role in Metastasis of Prostate Cancer
...ell itself. But this hypothesis didn't explain why metastases appear many years after the initial tumor. 'Our ...gues discovered a signaling pathway that increased metastases in a mouse model of prostate cancer. The pathway is activated by a ligand that binds to a Receptor t...Inflammation Promotes Metastasis of Prostate Cancer
...ell itself. But this hypothesis didn't explain why metastases appear many years after the initial tumor. "Our...gues discovered a signaling pathway that increased metastases in a mouse model of prostate cancer. The pathway is activated by a ligand that binds to a Receptor t...RF Ablation a Safe Alternative Option for Treating Lung Cancer
...cancers, including 116 primary lung cancers and 73 metastases to the lung from other cancers. The majority of the patients, who ranged in age from 17 to 94, also suffered from severe cardiopulmonary disease. The one, two, three, four and five-year survival rates for stage I, non-small cell lung cancer treated...Follow Screening Regimen for Early Cancer Detection
...the repeat rounds of screening) had no evidence of metastases when recommended for biopsy, indicating that a regimen of annual repeat screenings allows for detection of lung cancer at its earliest, most treatable, stage. Long-term follow-up, as shown in an International ELCAP study recently published in the New...Implications of Statin Therapy in Bladder Cancer Patients
...o underwent radical cystectomy, the number in whom metastases developed and the time to their development were similar in the two groups. The authors concluded that 'Our observations suggest that the discontinuation of statin therapy during BCG immunotherapy might improve the clinical outcome'. In the March i...Satraplatin Benefits Hormone Refractory Prostate Cancer Patients
...s and pain progressions. Pain associated with bone metastases is the dominant cause of morbidity in patients with metastatic HRPC. Increase in prostate specific antigen (PSA) was not part of the progression endpoint. PFS at the median demonstrated a 14% improvement in patients who received Satraplatin plus pred...Developing Antimetastasis Therapy- An Early Stage of Tumor Control.
...ly, it indicates that a drug target for lymph node metastases could be blocking the signaling molecule or its receptor on the tumor cell'....Sentinel Lymph Node Biopsy is Linked With Increase in Breast Cancer Rates
...rease, it is expected that cases with [lymph node] metastases also will continue to increase, the authors write....Novel Method to Inhibit Prostate Cancer
...xicity. Targeting drugs to disseminated prostate metastases is one of the most challenging goals in prostate c...in cautions that this inhibiting activity of tumor metastases growth was not absolute and that while the results are encouraging, there is a need for further rese...Gene Therapy Eradicates Pancreatic Cancer in Mice
...mours in nearby organs. There were no detectable metastases in mice treated with the VISA-BikDD combination. "All cancer drugs have some toxicity and so cause side effects, which affects the dose that can be administered. The VISA-BikDD produces virtually no systemically acute toxicity or acute pancreatiti......occurs to the liver and 15% of patients have liver metastases at the time of diagnosis. The latest human results reported today follow testing in the lab and in animals where the virus was shown to be effective at killing colorectal cancer cells and liver cancers. More information about ECLU is available at...EpiCept Accelerates Development of Phase I Clinical Study for Cancer
...s with primary brain cancer and the other in brain metastases due to melanoma. EpiCept's licensing agreement with Myriad for Azixa includes milestone payments, and sublicensing income as well as future royalties in the event Myriad's development of Azixa continues to progress successfully. <br...