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Tag: "metastases" at medical news

Response to chemotherapy could be measured by Prostate-Specific Antigen Doubling Time

...ry prostate cancer and bi-dimensionally measurable metastases in the lymph nodes or visceral organs. The investigators calculated PSA doubling time among the patients who had a rising PSA during chemotherapy. Patients' objective best response for any of the chemotherapeutic regimens they were taking was partial...

New Treatment for Some Cancers

...ity than current radio-isotopes used to treat bone metastases that are formed when tumor cells invade bone marro...nough energy to slow down or destroy tumors. Bone metastases act like a magnet to this kind of radioactive phosphorous compound, which collects near the cancer c...

Drug might prevent Prostate Cancer Spread

...dronate had a 21-percent reduction in risk of bone metastases and a 20-percent reduction in their risk of death. The researchers write, "Our results suggest that men treated with the bisphosphonate sodium clodronate have longer symptomatic bone progression-free survival times than men treated with placebo." Mo...

PET Scan May Be Beneficial After Cancer Treatment

... //reliably identified residual cancer and distant metastases or secondary tumors in patients with advanced-stage head and neck cancer. This result, researchers say, has a direct influence on health management decisions. Twenty-six patients with stage III or stage IV head and neck cancer had a PET scan before ...

Understanding Lung Cancer Metastasis

...anges up to 80 percent. Whether or not these brain metastases directly impact mortality from the disease, howeve...ad developed brain metastases. Patients with brain metastases had poorer survival rates than those without the distant cancer. About half of the deaths among thos...

Preventing Bone Metastasis In Patients With Breast Cancer

...t with clodronate not only delays or prevents bone metastases in patients with breast cancer, but also reduces t..., and mortality in those patients who develop bone metastases despite treatment at the time of occurrence....

Increased Risk For Venous Thrombosis In Cancer Patients

...s greater risk). Patients with cancer with distant metastases had a higher risk compared to patients without distant matastases (20-times greater risk). Cancer patients who also carry the V Leiden mutation had a 12-fold increased risk vs. individuals without cancer and factor V Leiden. Similar results were indi...

MRI with nanoparticles highly sensitive in detecting prostate cancer metastases

...ensitive in detecting clinically occult lymph-node metastases in prostate cancer, according to a new report. In ...team has also tested the agent's ability to detect metastases from lung and breast cancer and it appears to work equally well. "That's the beauty of targeting nor...

Drug might prevent Prostate Cancer Spread

...dronate had a 21-percent reduction in risk of bone metastases and a 20-percent reduction in their risk of death. The researchers write, “Our results suggest that men treated with the bisphosphonate sodium clodronate have longer symptomatic bone progression-free survival times than men treated with placebo.” M...

Researchers Identify Sipa 1 Gene, Responsible For Cancer Metastasis

...ibiton of Sipa1 decreased the numbers of pulmonary metastases from a highly metastatic mammary tumor cell line. Conversely, over expression of the FVB allele increased the numbers of pulmonary metastases. Analysis of human tumors also demonstrated that over expression of SIPA1 is associated with metastatic prog...

Measuring disseminated cancer cells in bone marrow - valuable tool for detecting early breast cancer metastasis

...breast cancer patients and the level of lymph node metastases is measured to determine the disease prognosis. But research results as shown that 30% of patients with lymph node negative status still develop metastatic disease. A new approach to overcome this has been found in which the detection of micrometases...

Obese Women At Increased Risk Of Developing Breast Cancer

... more likely to develop either regional or distant metastases compared to their counterparts with insignificant weight gain. Breast cancer risk is linked to increased lifetime levels of circulating estrogen. Fat tissue increases circulating estrogen, thereby adding to the risk. Previous studies have shown, th...

Researchers have Identified the Gene that Spreads Skin Cancer

...ause primary skin melanoma doesn’t kill patients – metastases are the major problem. So understanding the events that drive metastasis may lead to identifying the most relevant targets for therapy, and potentially, for preventing metastasis." More than 62,000 cases of melanoma will be diagnosed in the United ...

Listening to the Sound of Skin Cancer

...ise, and could let oncologists spot early signs of metastases -- as few as ten cancer cells in a blood sample --...ic systems, spreading to other organs and creating metastases even after the original melanoma has been surgically removed. An earlier metastasis warning, as th...

Diptheria Toxin And Interleukin2 Help Killing Melanoma Tumour Cells

...er four cycles, including subcutaneous tumours and metastases in the liver and lymph nodes. One patient had two tumours on the leg that had died and became infected, requiring surgery. When the researchers examined the tumour tissue they found that it was surrounded by CD8+ T lymphocytes. 'This meant that the...

Systemic Pre-Surgical Treatment Can Prolong Survival Of Kidney Cancer Patients

...ents were previously untreated, did not have brain metastases and had not undergone kidney surgery. They gave the patients bevacizumab intravenously once every two weeks for four doses, and erlotinib orally every day for eight weeks. Two weeks after the last dose of erlotinib and four weeks after the last dos...

A Combination Of Drugs Used For Anti-Angiogenesis And Apoptosis More Effective

...es, which showed increased inhibition of pulmonary metastases and primary tumour growth when both were used simultaneously. These findings are important because, if it proves to be effective in humans, it would be well tolerated and have significantly fewer side effects than traditional cytotoxic therapy. Als...

A novel vaccine proves a shot in the arm for colorectal cancer patients

...from a patient who survived seven years with liver metastases from colorectal cancer, Durrant explained. "This is very unusual as most patients die within one year of getting liver metastases," she said. "I thought if this antibody had helped this patient, if we could clone it, it might help others." 105AD7 i...

Stem Cells as Cancer Therapy

...lleagues report on the eradication of disseminated metastases in a mouse model of a cancer called neuroblastoma. The researchers took advantage of the tumor-tropic (selective migration towards cance r cells) properties of neural stem cells engineered to express an enzyme that activates an anti-cancer drug. I...

Suppression of Enzyme Delays a Type of Breast Cancer

...t tumor appeared almost eight weeks later and lung metastases did not happen. In some mice cancer did not develop at all. On the other hand, when the enzyme PTP1B was expressed it resulted in the development of cancer. Understanding of the relationship between this enzyme and breast cancer is likely to go a l...

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