Study Says - Blocking 'aP2' Protein Prevents Airway Diseases
...P2 has previously been considered to be a specific marker for fat cells. The group went on to show that mice lacking aP2 have a dramatic reduction in airway inflammation in a model of asthma. In addition, the infiltration into the airways of inflammatory molecules such as leukocytes and eosinophils was high...Bone Marrow Cells Aid In Heart Repair
...w cells were modified to carry a green fluorescent marker allowing researchers to easily track them. The researchers demonstrated that these bone marrow cells are quickly mobilized to the damaged heart region following a heart attack. Once in the damaged area, the cells produce chemicals that trigger the gr...Biomarker Reduces Length of Antibiotic Treatment
...apy response in such patients appears to be more a marker of ongoing inflammation than persistent infection,” Dr. Wunderink wrote. Although the therapy may reduce the duration of antibiotic treatment by an average of seven days, he noted that 14-day treatment of CAP is no longer standard. “Clinical trials...Procalcitonin-Guided Antibiotic Therapy Proved Effective in CAP Cure
...apy response in such patients appears to be more a marker of ongoing inflammation than persistent infection,’ Dr. Wunderink wrote. Although the therapy may reduce the duration of antibiotic treatment by an average of seven days, he noted that 14-day treatment of CAP is no longer standard. ‘Clinical trials...Analysis of Placenta Helps In Diagnosis of Autism At Birth
...r of any cellular abnormality in the placenta as a marker for Asperger Syndrome, an Autism Spectrum Disorder (ASD). The research team that was led by Dr Harvey Kliman research scientist in the department of obstetrics, gynaecology, and reproductive sciences at Yale School of Medicine had examined placentas ...Mental Stress Linked To Higher Risk Of Heart Disease
... a reduced endothelial function, which is an early marker of cardiovascular disease. “These results suggest that for some African American youth at-risk of high blood pressure, stress may also contribute to more rapidly declining endothelial function,” stated Gaston Kapuku, MD, PhD, associate professor of ...A New Marker For Type-2 Diabetes ?
...g test, but could not confirm if RBP4 is simply a marker for insulin resistance or if it actually causes i... Experts say the possibility of an early disease marker for type 2 diabetes is exciting.The findings may also encourage people to exercise more. More in...Vegetarian Diet Prevents the Development of Atherosclerosis
.... He said that a 37 percent reduction in a certain marker of inflammation in mice suggests that vegetable consumption may inhibit inflammatory activity. ‘It is well known that atherosclerosis progression is intimately linked with inflammation in the arteries,’ Adams said. ‘Our results, combined with othe...IMP3 the Novel Biomarker for Metastatic Cancer
...e that IMP3 is an excellent independent prognostic marker that can be used at the time of initial diagnosis ...h potential to develop metastasis, IMP3 provides a marker that can help identify those patients who might benefit from a different follow-up approach after pa...Low Carbohydrate Diet Still the First Choice for Diabetics
...continued to show improvement in hemoglobin A1C, a marker for long-term blood-sugar levels in diabetes. The paper published today in Nutrition & Metabolism, an open access journal [no subscription required (http://www.nutritionandmetabolism.com/home/)], also reports that seven patients who immediately swit...Functional Differences In Estrogen Receptor Could Be A Therapeutic Target
...rowth of breast cancer cells, and are an important marker in therapy; readable levels of estrogen receptor proteins are expressed in a large portion of human breast cells. Professor Thomas F. Deuel, M.D., a Scripps Research scientist who participated in the study said, 'The estrogen and anti-estrogen sign...HIV Vaccine for Monkeys Increases Survival Rates
...Medicine, the studies also identified a measurable marker of SIV vaccine effectiveness in monkeys -- something known as an immune correlate of vaccine efficacy. Further study is needed to determine if the immune correlate could predict the effectiveness of a vaccine against HIV in humans. 'Having an immun...Research on AIDS vaccine a wealth of information
...lper T-cells and suggest how they may be used as a marker to gauge the efficacy of these vaccines.' The wo...'This second finding provides us with an important marker to use in gauging the vaccine's performance,' says Letvin. 'By measuring the levels of central memor...Quality Of Dietary Carbohydrates May Determine Quality Of Eye Sight
...observed. "Perhaps a high-glycemic-index diet is a marker for an overall dietary or lifestyle pattern that increases the risk of developing AMD." A diet high in high-glycemic-index foods like white bread and french fries has a higher overall glycemic index than a diet based more heavily on low-glycemic-inde...Autoimmune Diseases – Newer Preventive Measure
...pha-GalCer, prompted the scientists to use it as a marker to examine the status of these cells in a mouse missing the Aire gene. That Aire knockout is a good model for humans with APS1. They found significantly fewer iNKT cells in the thymus, spleen, liver and bone marrow and severely impaired maturation ...Erosive esophagitis healing connected to acid control
...lts further support intragastric pH as a surrogate marker for assessing the efficacy of antisecretory therapy in GERD." Acid reflux disease is frequent persistent heartburn (burning pain and pressure in the center of the chest) on two or more days a week. It occurs when the valve between the esophagus and...Ultimate Destination of anti-depressant, Prozac
...n a mystery until now. By profiling the telltale marker proteins produced by different kinds of cells in the brains of adult mice, the researchers first defined discrete steps in the complex process, called neurogenesis, that converts unspecialized stem cells into mature, specialized neurons. Next, know...Gene Variants Linked to Early Heart Attack Discovered
...tics, the scientists say. "In order for genetic marker studies to translate into diagnostic tests with significant medical impact, discovery study results must be reproducible and applicable to a wide group of people," said Tom White, PhD, chief scientific officer at Celera Genomics. "Too often, when new...Cut Calories to Age Gracefully
...to oxidative stress, RNA can be useful as an early marker of oxidative damage and even aging,' said Arnold Y..., it is important to learn that RNA is a very good marker of aging damage. 'I'd never really thought about RNA before,' Holloszy said. 'Research has always...Researchers Purify Protein That Could Regulate Male Hormones
...searchers learned that consistent with reversing a marker of gene silencing (H3K9 methylation), the protein functions as a co-activator – in this case, a co-activator for the androgen receptor target genes. Using human tissue cultures, including prostate cells, Zhang and his colleagues found that over-exp...