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Tag: "marker" at medical news

New Transgenic Mushrooms Raise Hope for Mass Production of Human Drugs

...obacterium. The hygromycin resistance gene was a marker gene to help sort out the transgenic mushroom cells from the non-transgenic cells. Scientists then cut small pieces off the mushroom's gill tissue and added it to a flask containing the altered bacterium. Over the course of several days, as the bac...

First Bacterial Genome Transplantation Changing One Species to Another

...e transplantation. First, an antibiotic selectable marker gene was added to the M. mycoides LC chromosome to allow for selection of living cells containing the transplanted chromosome. Then the team purified the DNA or chromosome from M. mycoides LC so that it was free from proteins (called naked DNA). Th...

Infertility is Seen in Men With SLE

...E. Follicle-stimulating hormone (FSH) is a major marker of the function of the cells lining the seminiferous tubules and its higher levels in the group 2 SLE patients suggest testicular damage. The researchers point out that although it is not possible to predict which SLE patients will become infertile...

Early Indicator of Kidney Disease May Also Predict Risk of Pre-Diabetes

...-stage kidney impairment, also may be a very early marker forthose at risk of developing a condition known as pre-diabetes, a studyconducted by researchers at the University at Buffalo has shown. Pre-diabetes is diagnosed when the amount of glucose in the bloodstream begins to rise and remain above norma...

Does Amateur Boxing Cause Brain Damage?

...estive of brain damage after a fight. A particular marker for neuronal damage, neurofilament light (NFL), was four times higher in boxers within 10 days of the fight as compared with healthy non-athletes. These increased levels returned to normal after three months rest from boxing. In addition, the incre...

Novel Technology to Locate and Treat Tumors

...re a target for pHLIP. Acidosis is a physiological marker of many diseases and pHLIP feels acidity, said Reshetnyak. Therefore, pHLIP could also be used for monitoring of disease development and therapeutic outcomes. It might play very important role in the study of arthritis, ischemia and stroke. Lead a...

Smokeless Cannabis Delivery Device Found Efficient and Less Toxic

...rbon monoxide, or CO. A toxic gas, CO served as a marker for the many other combustion-generated toxins inhaled when smoking. The plasma concentrations of THC were comparable at all strengths of cannabis between smoking and vaporization. Smoking increased CO levels as expected, but there was little or n...

Role of Protein in the Development of Prostate Cancer Identified

... cells, and TRPM8 has been suggested as a specific marker and therapeutic target in prostate cancer. However, the regulation of and changes in TRPM8 during prostate cancer progression have remained unclear. In normal prostate epithelium, cells coexist in many stages of development/differentiation progres...

Genetic Marker Linked to Aggressive Prostate Cancer

...have discovered that a recently identified genetic marker for prostate cancer is linked to a highly aggressi...rs said. Knowing which patients carry this genetic marker also will guide doctors in how they treat the cancer. The Northwestern study showed a strong hered...

Fecal Bacteria, a Source of Contamination

... known fecal bacteria sources, or by looking for a marker within the genetic material that is associated with a specific fecal source. The results of the study revealed that cattle and wildlife were the dominant sources of fecal bacteria found in water and stream sediment samples at the main study site loca...

People With Inflammation in Blood Likely to Develop Alzheimer's Later

...oston. 'The production of these cytokines may be a marker of future risk of Alzheimer's disease.'...

Step-Based Guidelines in New Pair of Studies

.... "A 'mile' appears to be universally known as a marker of distance for walkers and runners to measure their activity achievements," said Werner Hoeger, Ed.D., FACSM, lead author. "To estimate the number of steps required to walk or run a mile at selected speeds is likely to help people who monitor their ...

Patients With OSA at Higher Risk for Cardiovascular Disease

...g for circulating apoptotic endothelial cells as a marker to fine-tune the therapy is one potential application. This may potentially reduce OSA patients risk of CVD. Dr. El Sohl mentioned that statins, angiotensin converting enzyme inhibitors, and vitamin C reduce enthothelial apoptosis, but it is not know...

Fertility Test at Home Possible With a New Kit

...est for women that measures a hormone considered a marker of egg quality. The availability of the two-in-one test helps drive home the message that both men and women can contribute to infertility, experts say. It takes two to have a baby, as silly as that sounds, said Dr. Harry Fisch, director of the Mal...

Brain Tumor Patients Survival Depends on Predicting Treatment Responses Earlier

...We studied the predictive value of PET with FLT, a marker of cell proliferation, in patients with recurrent malignant brain tumors, said Chen. "We used molecular imaging to measure the changes of metabolism in tumor cells," and FLT-PET provided much higher response rates than MRI, she explained. Additionall...

Pazopanib Shows Positive in Advanced Renal Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

...vity (measured as a decrease in CA-125, a biologic marker of clinical activity) was seen in nine (41%) of 22 evaluable patients with relapsed disease. The most common AEs were diarrhea, nausea, abdominal pain, fatigue, and vomiting. Please see safety considerations below. Globally, ovarian cancer (204,000...

Insufficient Sleep Increases Risk of Cardiovascular Disease: Study

...stresses and stimuli. Reduced variability can be a marker for cardiac problems and other diseases and has been linked to high blood pressure. "The effect of the sleep deficit was to increase the stress on the hearts of these volunteers," said Siobhan Banks, a lead author on the study. "If our finding is...

Blood Test Reveals Colon Cancer Proteins

...particular concentration of scaffold-proteins as a marker for disease, the Johns Hopkins team - which did not know the colonoscopy results in advance -- were 100 percent accurate in identifying the 28 existing cancers. Using the same protein markers, investigators also correctly identified 51 of 53 individu...

Intensity of Rheumatoid Arthritis Significantly Reduced by Pregnancy

...Activity Score DAS28 and the level of inflammation marker C-reactive protein (CRP). Disease activity was calculated with DAS28-CRP with 3 variables (DAS28-CRP-3). The change between the DAS28 at first and third trimester was used to categorise patients according to the EULAR response criteria into good, ...

Rejection in Lung Transplants Due to Elevated Pepsin Level

...igh levels of pepsin, a digestive enzyme that is a marker for gastric aspiration, are associated with acute rejection of a lung transplant , according to researchers in the United Kingdom . This research provides further evidence that lung rejection may be caused by factors other than alloimmunity, the att...

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