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Tag: "mammalian" at medical news

The route to fertilization

...o extract from them.If nitric oxide is involved in mammalian fertilisation, Epel, says that it could be useful in genetic engineering, cloning and in vitro fertilisation. Not to be confused with nitrous oxide, or 'laughing gas', nitric oxide plays an important role in human physiology. It maintains blood pres...

Reasons why men die earlier

...vide a larger target for parasites. Owens notes in mammalian species where females are larger in size than males, it is the females who are more susceptible to parasitic infections....

Inflammation Linked to Colon Cancer

...took the damaged DNA molecule and inserted it into mammalian kidney cells to see if it would replicate, and it did. The mutations seen in the study are similar to those known to cause an inherited form of colon cancer. The investigators conclude chronic inflammation causes genetic abnormalities that might lea...

Gene is related to premature ageing disease

...at lead to the physiology of mammals and reside in mammalian cell nucleus. Fibroblasts from the individual with the disease have severe abnormalities in the nuclear envelope structure. Scientists have not only identified the gene responsible for the progeria syndrome, but they have developed a process to rev...

New medicine for ovarian cancer

...ls.//The new medication targets an enzyme known as mammalian target of rapamycin (mTOR). The drug stopped the cells so that they cannot divide anymore or move o a different location and spread the cancer. The drug also reduces the cells ability to get nourishment from the blood vessels by a process called angi...

Cholesterol Mystery Solved By Nobel Laureates

...eedback response. They create mice lacking the two mammalian Insig genes -– Insig1 or Insig2 in the liver. On a normal chow diet, the mice over accumulate cholesterol and fats in the liver, but levels of SREBP's and other SREBP target genes (molecules that sense cholesterol and regulate its synthesis) were not...

Citrinin, a fungal toxin, induces apoptosis via mitochondrial pathway

... is known to be cytotoxic and genotoxic to various mammalian cells. CTN has been suggested as a causative factor in renal disease among poultry, pigs, dogs and rats. Many fungal toxins, including ochratoxin A, trichothecene, fumonisin B1, are known to trigger cellular apoptosis, which is a highly regulated ce...

Scientists breaking theory of cortex formation

... the specific functions and areas of the postnatal mammalian brain. Source: Eurekalert...

Mode Of Action Of The Anti-Convulsant Valproate

...ppression of AR-mediated NF-êB activation in human mammalian cells. By contrast, CBZ had no significant PR, AR or ER agonist or AR and ER antagonist bioactivity but at the highest concentration tested it did antagonize PR activity. The authors writing in the journal Steroids (available online 13 September ...

The Chemistry Of Sexual Attraction Between Male And Female Elephants

...d possibly understand the mating behavior in other mammalian species....

Malaria Can Develop In Lymph Nodes Also

...t Ménard. This reportedly has implications for the mammalian immune response. // The dreaded disease is caus... degraded, and were also seen interacting with key mammalian immune cells, suggesting that the immune cells were destroying them, a small number of the parasites...

Inactivation of Rad9 in Tumor Cells Would Be Advantageous In Cancer Therapy

...arnes-Jewish Hospital said that // inactivation of mammalian Rad9 in Tumor Cells Would Be Advantageous In Cancer Therapy. Rad9 checks for DNA damage, and fixes dangerous breaks in the DNA double helix. It is active in telomeres which are the protective ends of chromosomes. Hence Rad9 has gained a lot of im...

Switching Off Protein Could Play Key Role In Success Of Radiation Therapy For Cancer

Switching off a mammalian protein called Rad9 could hold the key to killing cancer cells easily with ionizing radiation, according to new research at Washington University School of Medicine in St. Louis. Rad9 was previously thought // to be a "watchman" for DNA, but it is n...

Australian Snake Venom Can Arrest Bleeding During Surgery And Trauma

...e source for generation of Factor X, excluding the mammalian livers. The mass delivery of Factor X results in inactivation of specific human systems, resulting in death. QrxPharma, a pharmaceutical company is currently considering the initiation of clinical trials of the potential 'life-saving drug'. The stu...

The Little Known Facts of Junk DNA

...xpress. The researchers used the zebrafish to test mammalian DNA and identify DNA sequences, known as enhancers. These sequences are involved in turning on a gene. They took the particular RET gene which is associated with Hirschsprung disease and multiple endocrine neoplasia (MEN2). Researchers identified D...

Hearing May Be Regained: Research Provides Hopes

... vestibular hair cells, so it's not the first time mammalian hair cells have been made to regenerate but it's the first time in the ear”. “In terms of therapeutic applications, that's definitely going to be a long way ahead - 10 or 20 years. The issue is going to be the control of reproliferation, and these ...

Scientist Optimistic In Breakthrough For Causes Of Neurodegenerative Diseases

...are from the most detailed proteomic analysis of a mammalian brain to date – that is, a survey of nearly 8,000 different, detectable proteins in the mouse brain. The research suggests that many neurodegenerative diseases leave a biochemical calling card, or biomarker, that could be used to predict the earliest...

Renewable Oocytes of Mice created hope in Human Fertility Treatment

...lished in the July issue of Reproduction. In the mammalian ovary, reproductive cells called oocytes (eggs) develop within ovarian follicles. In humans, the eggs are believed to die off from late in foetal life, after birth and into adult life. When egg numbers decline towards zero females can no longer repro...

Antibiotic Proved Protective against Heart Tissue Damage and Cell Death – Research Find

...pamycin blocks protein synthesis by inhibiting the mammalian target of rapamycin (mTOR), an essential component in the pathway of the cell cycle progression. The drug has been found to be important in transplant medicine and especially in kidney or heart transplantation. Additionally, Kukreja said that because...

Cancer Research: Yet Another Milestone

...ing an approach that randomly alters expression of mammalian cell genes, together with a screen that detects altered gene function, Dr. Cohen and colleagues identified a previously uncharacterized gene, called txr1, whose increased expression in prostate cancer cells confers resistance to taxane drugs. Taxanes...

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