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Tag: "macrophages" at medical news

Molecule aids fight E. Coli Infections

...h-and-destroy missions by white blood cells called macrophages against// the Escherichia coli bacteria. Most E.... warrior forces that fight such infectious agents, macrophages destroy the enemy by ingesting it in a process called phagocytosis. The researchers detailed these d...

Lymph Cell Growth In Eyes Related To Macrophages

...chool had discovered a kind of immune cells called macrophages are behind the growth of new lymph vessels in the ...earchers began to suspect a new connection between macrophages and lymph vessels while studying corneal transplants in mice. They had become aware of lymph vessels...

Vitamin D May Help In Fight Against Tuberculosis

...however poorly understood in human beings. Human macrophages have a set of receptors (toll like receptors) that contribute to innate immunity. It ahs now been shown that this may be to a large extent dependent on absorption, storage and utilization of Vitamin D. Stimulation of toll like receptors by specific m...

Study Would Pave Way for the Development of New Drugs That Targets TB Proteasome

... kept in check within immune system cells known as macrophages by compounds such as nitric oxide that kills or disables most of the bacteria. Inside the macrophage the immune cells damages and destroys the bacterial proteins. These accumulated proteins have to be removed otherwise it will in turn destroy the cel...

Tumor Resistant Mice Point To Novel Cancer Treatments

...led cytolysis. A combination of WBCs (neutrophils, macrophages and natural killer cells) from the special mice was then injected into mice with tumors. As expected, these injected cells were found to destroy the tumor, even the most aggressive forms. More importantly the healthy tissue was unaffected and norma...

Nanotechnology Could Revolutionize Cardiac Treatment

...e opposite effect,’ he said. Mogue explains that macrophages accumulate large amounts of oxidized LDL and secrete chemicals that can damage the neighboring tissues and, ultimately, become fatty foam cells. The researchers' approach, therefore, is to create clusters of nanoengineered molecules that target speci...

'Oncomodulin'- Path To Nerve Regeneration

...an inflammatory reaction occurred which stimulated macrophages which are immune cells to move into the axons and release an unidentified protein which causes nerve regeneration. But for oncomdulin to work it requires an agent which should increase cyclic AMP which initiates various cellular reactions and helps m...

Link Between Immune System And Nervous System

...e Emend, might also block HIV infection. Because macrophages are a reservoir for HIV, a strategy that denies th...er NK-1R antagonist blocked HIV replication within macrophages in cell culture. The hope is that aprepitant may show a similar protective effect in patients. "We...

Well-Planned Surgeries Also Carry Health Risks

...st.” The mice die rapidly and these re-programmed macrophages may help explain why children with sickle cell disease are more prone to overwhelming and potentially deadly infections following surgery. “We need more investigations, more data on humans,” says Dr. Meiler, noting that while short-term outcomes of ...

Best out of waste: Microbiological revolution!

...Pittsburgh. Isolation and characterisation of 30 macrophages has been made possible by digging in the backyard. // PLoS Genetics issue of June 9, 2006 has a report of a research team lead by HHMI professor Graham Hatfull at the University of Pittsburgh. The report is about the characterization and cataloguin...

Lack of STAT1 -an Immune Protein, Pack Liver Infection Cure

...the parasite from the body. These cells are called macrophages – a kind of garbage collector for the immune syste...in mice without STAT1 because there weren’t enough macrophages in the liver for the parasite to infect, and these are the very immune cells that are essential for ...

Cancer Drug Helps An Anti-Cancer Virus To Act More Exhaustively

...he virus, she found that high numbers of NK cells, macrophages and brain-tissue immune cells called microglia had moved into the tumour. The number of macrophages, for example, had raised three fold. In animals given the drug, on the other hand, the number of these immune cells increased by only one half. Othe...

Reducing the Risk of Protease Inhibitor-Related Atherosclerosis

...ctions by consuming unwanted materials. CD36 spurs macrophages to eat cholesterol: The more CD36 the body produces, the more cholesterol the macrophages consume. The problem occurs when cholesterol-laden macrophages get stuck in artery walls. Over tim...

Researchers Discover Breakthrough in Major Third World Scourge

... Medicine indicate that during helminth infection, macrophages differentiate along an alternative activation path...y. Dr. Gause said that this research shows us that macrophages mediate clearance of these parasites and this insight may lead to more effective treatments of this ...

Gene Transfer Using Mutant Form of Good Cholesterol Cuts Vascular Plaque and Inflammation

...hey facilitate the removal of cholesterol from the macrophages in the plaque and deliver it to the liver for elim...experiment and all three methods demonstrated that macrophages containing the apo A-I Milano gene were more effective in effluxing cholesterol out of them, compare...

Salmonella Bacteria Are Deceptive

...r this bacterium invades by stealth and hides from macrophages before entering them and multiplying inside them. This is ironical since macrophages are the cells meant to detect such bacteria. Just how Salmonella escapes detection by macrophages,...

An Infectious Agent of Deception, Exposed Through Proteomics

...r processes linked to Salmonella’s colonization of macrophages in humans, said Joshua Adkins, a co-author on Shi’...eparate and identify many proteins at once even as macrophages were being infected. Most of the initial candidates were designated “house-keeping” proteins, or t...

Chemical in Curry May Help Immune System Clear Plaques Found in Alzheimer's

...ts, including amyloid beta. The team treated the macrophages with a drug derived from curcumin for 24 hours in ... culture and then introduced amyloid beta. Treated macrophages from three out of six Alzheimer’s disease patients showed improved uptake or ingestion of the waste ...

Pomegranate juice may cut atherosclerosis risk in diabetics

...ed LDL or “bad” cholesterol by immune cells called macrophages helps in the development of atherosclerosis. Pomegranate juice seems to prevent this uptake. According to the lead researcher Professor Michael Aviram of the Technion Faculty of Medicine, though the sugars present in pomegranate juice were similar ...

Anti Atherosclerosis Therapies Linked to Leukemia

...in chronic inflammation. The acute response of the macrophages to infectious agents like bacteria, critical for protection against disease, remained unfettered. "We and others had hoped that blocking this enzyme would safely slow or stop certain chronic inflammatory responses that have been linked to atheroscle...

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