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Tag: "machinery" at medical news

Autophagy may Lead to Heart Disease

...Frank M. Ryburn Jr. Chair in Heart Research. The machinery of autophagy in mammalian cells is not completely understood and even less is known about its function in disease, he said. The autophagic response may also differ in distinct kinds of heart failure, highlighting the need for further study of autopha...

Smoking Speeds Up Muscle Loss

...de that smoking slows the muscle protein synthesis machinery - probably impairing day to day upkeep of muscle. We are all well aware of the ill affects of smoking on the lungs but our study reveals yet another cause of ill-health associated with smoking. Hopefully the UK smoking ban will encourage people to qu...

Key Mechanism to Emergence of Strep Bacteria

...ur hard drive, this virus reprogrammed the genetic machinery of the M1T1 strep into a more virulent form, said senior author Victor Nizet, M.D., UCSD Professor of Pediatrics and Pharmacy. The consequences of this event on human health are still being felt three decades later.The research, reported in the Jul...

First Drug for Post-traumatic Stress Disorder

...aid, studies have shown that some of the molecular machinery that initially encodes the troubling memories also regulates their extinction. In the current work, genetically engineered mice received mild foot shocks in a certain environment and were re-exposed to the same environment without the foot shock. ...

Giant Microwave That Recycles Plastic Back into Diesel, Gas

...ook just like an industrial microwave with bits of machinery attached to it. Larger versions resemble a concrete mixer, reports New Scientist. According to Meddick, the Hawk-10 will be very useful to the recycling industry. Whatever does not have a hydrocarbon base is left behind, minus any water it containe...

Treaty With Japan may Legalize Dumping Toxic Waste in India

... contentious issue is the amount of electronic and machinery waste that comes into India from Japan. Currently, soft loans to India from the Japan Bank for International Cooperation (JBIC) and grants from the Japan International Cooperation Agency (JICA) range between $25 million-$33 million a year. JICA...

Cancer Cells Reprogram Energy Needs To Grow And Spread

...m themselves to turn down their own energy-making machinery and use less oxygen, and that these changes might help cancer cells survive and spread. The Hopkins scientists report that the loss of a single gene in kidney cancer cells causes them to stop making mitochondria, the tiny powerhouses of the cell th...

Scientists Map Genome Sequence Dengue Mosquito

...d by the host -- the individual organism's genetic machinery --to perform biological functions," Tu added. The researchers believe that TEs may be developed as genetic tools to study the interaction between mosquitoes and pathogens, and thus may lead to controls of transmission of disease. They said that ...

$5M Gift Will Attack Lou Gehrig's Disease

...ells to increase the number of times their genetic machinery reads the genetic blueprint for those growth factors. Preliminary results show that injecting that snippet, called a zinc finger transcription factor, into cells causes more of the growth factor VEGF to be produced and enhances nerve regeneration. F...

Enriching Environment Stimulates Neurons: Hope For Fragile X Syndrome

...nvironment can restore the malfunctioning neuronal machinery of Fragile X syndrome . The findings have been published in the May 24, 2007 issue of the journal Neuron, published by Cell Press. A type of inherited mental retardation; Fragile X syndrome affects 1 in 3600 males and 1 in 4000 to 6000 females. The...

Novel Markers for the Treatment of Bipolar Disorder

...ities in neuronal plasticity cascades the complex machinery inside of nerve cells that regulates numerous processes inside the body. Using animal and cellular models, Dr. Manji and colleagues at NIMH showed that disruptions in these pathways resulted in many of the core symptoms of bipolar disorder and expl...

Polio Cases In The Country

...r involvement of State and District administrative machinery ? Deploying high level officials from UP and Bihar to monitor PPI activities ? Increased focus on mechanisms to reduce missed children in west UP ? Improving vaccination team performance by re-training vaccinators and supervisors to improve th...

Penn Scientists Engineer Small Molecules to Probe Proteins Deep Inside Cell Membrane

...PHIA -- Proteins, which form much of the molecular machinery required for life, are the targets of most drug molecules//. One third of all proteins are membrane proteins – embedded within the cell’s fatty outer layer. While scientists can easily study the other two-thirds using such tools as antibodies, they h...

Viral Enzyme Recruited in Fight Against Ear Infection

...e inside, the virus hijacks the cell’s biochemical machinery and forces it to make many copies of the virus. After the new crop of viruses is made, a viral enzyme breaks apart the infected bacterial cell wall and allows the new viruses to escape and infect additional cells. The success of the new treatment,...

Successful Islet Cell Transplant in Mice With Type 1 Diabetes

...suppressor protein that is broken down by cellular machinery called proteasomes. In cancer patients whose tumors do not produce p53, proteasome inhibitors might be ineffective. This patient group could be spared unnecessary treatment with possible harmful side effects. On the other hand, proteasome inhibito...

An Anti-rabies Campaign With Bite

... a major health hazard in India and the government machinery not equipped to cope with the problem, it remains to be seen if the authorities realise the potential of the non-governmental organisations like PFA which runs Asia's biggest animal hospital ASHARI here besides a huge cat shelter. Said WHO chief sp...

Natural Brain Substance Linked to Parkinson's Symptoms

...rain to transmit signals - form part of the neural machinery that directs normal physical movement. A shortage of the endocannabinoids, the scientists found, can knock the system out of balance to produce the characteristic tremor, rigidity and other mobility problems of Parkinson's disease patients. The ...

Scientists Discover New Gene

...known as 1p36. When CHD5 is not doing its job, the machinery within our cells that normally prevents cancer is switched off. The ability of CHD5 to function as a master switch for a tumor suppressive network suggests that this gene is responsible for a large number of diverse forms of human cancers. "CHD5 f...

How Bacteria Generate Energy to Live?

...at the cofactors — important parts of the enzyme’s machinery — are all located on the inner side of the membrane, which corresponds to the "intake" port of the ion pump. The second paper was published in the Journal of Biological Chemistry. In this study, Barquera focused on structures, known as flavins, wit...

Drug Strategy Makes Cancer Genes Get Lost in Translation

...weak mRNAs serves as an obstacle for the ribosomal machinery that does the translating, making it a challenge to determine where to begin, he added. In contrast, strong mRNAs have only short 5' untranslated regions that allow for easier protein formation. The successful translation of weak mRNAs therefore d...

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