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Tag: "mab" at medical news

Transplanted heart made more acceptable by daclizumab

Daclizumab has been found to reduce the risk of cellular rejection after a heart transplant// when used on top of standard immunosuppression. ....The drug, a humanized monoclonal antibody, is directed against the interleukin-2 receptor, thereby inhibiting T-cell proliferation. ....Patients who were taken into the Study were either given daclizumab or a placebo. ....The primary endpoint was a comp...

The Benefits of abciximab with clopidogrel for percutaneous coronary intervention Questioned

Primary findings from the Intracoronary Stenting and Antithrombotic Regimen-Rapid// Early Action for Coronary Treatment Trial (ISAR-REACT) has indicated that abciximab use in patients undergoing percutaneous coronary intervention (PCI) after pretreatment with 600 mg clopidogrel for less than 2 hours offered no clinically measurable benefit at 30 days. .. ..The trial included 2159 patients undergo...

Merck and Takeda to collaborate in the sale of Cancer drug Matuzumab

Merck Pharmaceuticals from Germany and Takeda Pharmaceuticals from Japan to colloborate in marketing of Merck's cancer drug Matuzumab. .. ..Matuzumab is developed by Merck which is in its Phase II // clinical tiral. Takeda Pharmaceuticals will sign agreement with Merck to give royalty and sale benefits from the sale of Matuzumba. Takeda will pay 60 million euros to Merck with an addition of roya...

Trastuzumab therapy effective for Breast cancer patients with Her-2/neu positive

Researchers Edith Perez and Edward Romond reported from two separate trials that Breast cancer patients with Her2-positive were effectively treated with Herceptin therapy using trastuzumab. //The results of their study were published in the journal The New England Journal of Medicine. The researchers compiled results from two clinical trials, which compared patients getting only chemotherapy with...

Bird Flu Outbreak Confirmed Near Islamabad In Pakistan

A second outbreak of the deadly H5N1 bird flu strain was reported in a poultry farm near Pakistan's capital Islamabad on Sunday. // ...."During an ongoing surveillance for avian influenza, a suspect outbreak was reported at a small poultry farm in Sihala, some 25 km from Islamabad on Friday," livestock and animal husbandry commissioner Muhammad Afzal said. ...."Clinically, the disease was sugg...

Two More Human Bird-Flu Suspects Taken To The Hospital In Islamabad

Two more patients have been admitted to the hospitals in the twin cities,following symtoms of cough, cold and fever. They are being investigated for the bird flu infection. // ....With this , the total number of cases reported so far touches 9. The health ministry has confrimed that no H5N1 strain has been detected any where in the country. Nearly 29,000 chickens have been culled ever since the...

Adalimumab Proves Effective for Children with Juvenile Rheumatoid Arthritis

Adalimumab, an injectable anti-TNF therapy that has FDA approval for treating rheumatoid arthritis in adults, has proven effective in children with juvenile rheumatoid// arthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Washington, DC. ....The immunosuppressant adalimumab, currently used to treat adults with moderate to seve...

Islamabad Bans Hookah Smoking in Public Places

Authorities have banned the use of hookah, or hubble-bubble, in the Pakistani capital saying that besides being a serious health hazard they were spoiling the younger// generation. ....A way of relaxation, either individually or in company down the ages across South Asia and the Middle East, the hookah, known as 'sheesha' in Arabic, is now popular in all major hotels and motels in Pakistan, The...

Crucell's Rabies MAb Enters Phase I Trial in India

Dutch biotechnology company, Crucell N V’s Rabies monoclonal antibody (mAb) product has entered a phase I clinical study in India, four months after launching// a similar study in the US. .. ..Crucell has developed a human monoclonal antibody product for the post-exposure prophylaxis of rabies, using Crucell’s MAbstract and Crucell’s PER.C6 technologies. This second phase I study is closely link...

Denosumab Reduces Bone Erosion

According to results of a 227 patient Phase 2 trial presented at EULAR 2007, the Annual ...Treatment with denosumab 60 mg and 180 mg (with background methotrexate) reduces the progression of bone erosion . ...Denosumab is a fully human monoclonal antibody which binds to and inhibits the RANK Ligand. The RANK Ligand is the essential mediator of osteoclast formation, function, and survival and th...

Abbott's Humira(r) (Adalimumab) Gets Approval by EU for Crohn's Disease Treatment

ABBOTT PARK, Ill., Abbott announced today that it has received marketing authorization from the European Commission for the use of HUMIRA(R) (adalimumab) as a treatment for severe Crohn's disease. HUMIRA is the first self-administered biologic for the treatment of Crohn's disease and offers an effective and convenient treatment option that can help enable patients to maintain control of their di...

Why Malaria Parasite Affects Red Blood Cells Deformability Revealed

A study led by researchers at the Massachusetts Institute of Technology (MIT) has found out why red blood cells start to lose their ability to deform, and squeeze through tiny blood vessels during the first 24 hours of invasion by the malaria-inducing parasite Plasmodium falciparum. ...The researchers knocked out the gene for a parasite protein called RESA (ring-infected erythrocyte surface an...

Islamabad Culls Over 6,000 Birds Control Bird-flu Outbreak

Authorities have culled more than 6,000 birds to control a new outbreak of avian flu at three poultry farms in Islamabad, capital of Pakistan, an official said Wednesday. ......Laboratory tests confirmed the presence of H5N1, a strain of avian influenza that is deadly in humans, at three farms in Chak Shehzad, where about 12,000 birds died mysteriously this week, said Mohammad Afzal, spokesman...

Harvard to Develop Medical City in Islamabad

Harvard Medical International (HMI) will build a 60-acre health and education complex in Islamabad to cater to the health and medical needs of the people of the capital and the twin city of Rawalpindi . ......The complex is part of a large-scale residential development plan to develop a Health and Education City in the capital, and includes a 500-bed teaching hospital and colleges of medicine, n...

Study Confirms Benefits of Chemo, Trastuzumab Combo to Battle Breast Cancer

The meta-analysis of five major breast cancer trials has confirmed that a combination therapy of chemotherapy and antibody trastuzumab chemotherapy improves survival in women with operable HER-2 positive breast cancer. ......Issa Dahabreh from the University of Athens conducted the meta-analysis of 5 trials involving more than 13,000 women whose breast cancer was amenable to surgery, and found...

Combination of Tratuzumab and Chemotherapy Yields Better Results for Breast Cancer

A recent meta-analysis of five major breast cancer trials has confirmed that combination treatment with the antibody trastuzumab and chemotherapy improves survival in women with operable HER-2 positive breast cancer. ......At the ESMO Conference Lugano, Issa Dahabreh from the University of Athens reported the results of a meta-analysis of 5 trials involving more than 13,000 women whose breast c...
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