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Tag: "lymphocyte" at medical news

New Treatment Boosts Survival Chances for Child Leukaemia

...highly effective against lymphoblasts, as immature lymphocyte cells are called. At the 38-month followup mark, 260 (58 percent) of the patients who received this "hybrid" treatment were in complete remission. Meanwhile, a separate study, also published in The Lancet, highlights new combination chemotherapy ...

Memory T Cells Protect the Body from Viruses

...the skin, the lungs or the gut). This process of lymphocyte multiplication and migration may take several days while viruses multiply and spread quicker. Sigals work shows the CD8 T cells can protect from viral disease without the need to migrate from the lymph nodes to the site of viral entry. It was very ...

Body's Defence Mechanism Against Viral Disease Discovered

...uld win this race," said Sigal, because process of lymphocyte multiplication and migration may take several days while viruses multiply and spread quicker. The researchers say that their experiments have shown the ability of memory T cells to rapidly multiply and kill target cells inside the lymph node. "In ...

Lymphocyte Count Found to Be a Predictor of Survival for Young Patients With Leukemia

...s over the past decade has shown that the absolute lymphocyte count (ALC), a measure of normal immune cells foun...m the study showed that AML patients who had a low lymphocyte count on day 15 of treatment had a five-year overall survival chance of only 28%. However, patients ...

Major Gene Study Uncovers Secrets of Leukemia

...ely to directly contribute to this block in normal lymphocyte differentiation, according to Downing. These genes encode proteins called transcription factors, which orchestrate the expression of a large number of other genes involved in B cell development. Together these genes coordinate the complex changes nee...

A Single Biological Mechanism Behind Several Autoimmune Disorders

...lobulins and IGF-1R as a cause of inflammation and lymphocyte infiltration in both Graves’ disease and rheumatoi...rminant of immune responses through fibroblast and lymphocyte activation and expansion. This further implicates IGF-1R in the pathogenesis of patients with Graves...

Lymphocyte/WBC Ratio Helps in Treating ENT Disorders

...croliter vs. 11,400 cells per microliter), but the lymphocyte count was higher in the mononucleosis group (6,490 cells per microliter vs. 1,590 cells per microliter). The ratio of lymphocyte/white blood cell count ratio averaged .54 in the mononucleosis group and .10 in the tonsillitis group. Based on this d...

Aggressive Stem Cells Might Improve Transplant Outcome

...tem cells receive their “marching orders” as new T lymphocyte warriors against invading bacteria, viruses and other potentially dangerous targets including cancer cells, and they develop a specialized homing mechanism called a T cell receptor that lets them find the specific target they are genetically programm...

'Good' And 'Evil' Clones Of Acute Lymphoblastic Leukaemia cells

...re. Therefore, we can 'molecular fingerprint' each lymphocyte in order to know what the leukaemia 'looks' like. We found 'fingerprints', or clonal markers, that revealed the emergence or evolution of new clonal populations at the time of relapse in 13 patients. In eight of the samples, highly sensitive clone-sp...

HD Type Plays an Important Role in the Survival of the Patient

...ncer. //It revealed the fact that the HD type with lymphocyte predominance had the best prognosis. There were significant differences existed between the disease prevalent in U.S. and Europe. HD is a malignancy of the lymphatic system of the body, which includes lymph nodes and the spleen. Like many cancers, HD...

Mouse Models To Determine The Cause Of Aggressive Leukemia

...survival. They soon found that it might be the B lymphocyte stimulating protein IL-7. It is produced in the bone marrow enhancing the proliferation of cultured leukemic cells removed from the mice and made the cells resistant to imatinib’s growth inhibitory effects. It binds to receptors on the surface of lym...

Chronic Exposure To Benzene May Result In Dysplasia

...ed by clonal T cell expansion and alterations in T lymphocyte subsets. No clonal cytogenetic abnormalities were observed. . The authors conclude that these observations indicate that previous chronic exposure to benzene is associated with the development of BM dysplasia, and suggest that a reactive inflammator...

Genetics linked to leukemia treatment success rate in children

...eukemia (ALL) is a form of cancer that affects the lymphocyte producing cells. In ALL, there is an accumulation of lymphocyte precursor cells, also called blast cells, in the bone marrow. The researchers had used a process ca...

Infants going to day-care may have lower risk of leukemia

...eukemia (ALL) is a form of cancer that affects the lymphocyte producing cells. These cells stay in the bone marr...dy’s immunity. In ALL, there is an accumulation of lymphocyte precursor cells, also called blast cells, in the bone marrow. The results of the study showed that ...

Dementia linked to HIV

...at age, sex, education, risk behaviors, HIV stage, lymphocyte count, and antiretroviral therapy. Participants were considered cognitively impaired if they had poor scores on at least two of seven different neuropsychological tests. Researchers found that addition to the protective effect of antiretroviral ther...

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