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Tag: "islet" at medical news

Decoding Protein Structures Helps Illuminate Cause of Diabetes

...linked to toxic clumps of the protein hIAPP (human islet amyloid polypeptide), which is normally produced by the same cells that make insulin. An unknown trigger prompts the protein to fold into sharp fibers that poke holes in pancreatic cells, killing them. Though scientists already have a good idea of...

New Analytical Tool to Unravel the Cause of Diabetes

...linked to toxic clumps of the protein hIAPP (human islet amyloid polypeptide), which is normally produced by the same cells that make insulin. An unknown trigger prompts the protein to fold into sharp fibers that poke holes in pancreatic cells, killing them. Though scientists already have a good idea...

First-Ever Robotic Pancreatectomy Performed at UIC

...bilitating pain. They also performed an autologous islet cell transplant to prevent him from developing sur...roducing cells of the pancreas, called islets. The islet cells were then taken back to the operating room, where they were injected through a catheter into a...

LCT Reports Major Step for Islet Transplantation in Diabetes Patient

...es the survival and identification of live porcine islet cells and insulin production// in a human patient 10 years after receiving a pig islet cell transplant. The scientific paper outlines how LCT has demonstrated the long-term safety, via...

Transplanted Pig Cells in Human Produce Insulin

... the survival and identification of //live porcine islet cells and insulin production in a human patient 10 years after receiving a pig islet cell transplant. The scientific paper published in the March 2007 issue of the international jour...

Pigs Arrive at Bio-secure Center

...ween humans, followed this. Says Herring, 'Human islet cell transplants have reversed diabetes in 90 perc...n donor organs greatly limits the applicability of islet transplants. Pig islets will solve this demand issue and are at the forefront of a far-reaching cure...

Role of Appetite Hormone MCH in Insulin Production Revealed

...immune process has destroyed the insulin-producing islet cells in the pancreas. In type 2 diabetes, the far...that MCH and its receptors are indeed expressed in islet cells of mice and humans. They then treated human donor or mouse pancreatic islet cells with MCH and...

Stem Cells Passed From Mother to Child Live On and Make Insulin

...ad, the researchers found a small number of female islet beta cells in male pancreatic tissue (procured from autopsies) that produced insulin. Microchimerism is the term used when an individual harbors cells or DNA that originate from another genetically distinct individual. "To our knowledge a maternal ...

Highlights from World Transplant Congress

...ression, to groundbreaking studies of pancreas and islet cell transplantation for treatment of diabetes. ? Dr. Pekka H?yry, who performed critical experiments showing how immune system cells respond to and kill foreign cells after transplantation. Dr. H?yry also performed landmark studies of the diagnosis...

Type 1 Diabetes Linked to Stimuli from Nervous System

...stood to be the reason behind the damage caused to islet cells in the pancreas where insulin is produced. ...iscovered that there is a perceptible link between islet cells of pancreas, and the associated nerves that sense pain and other stimuli assonated with trauma...

New data from NIH lab confirms protocol to reverse type 1 diabetes in mice

... 1 diabetes and on the role of the spleen cells in islet regeneration. "This data from the NIH and the ea... but also allowed the insulin-producing pancreatic islet cells to regenerate. Evidence indicated that the spleen cells were the source of at least some of th...

New Device To Monitor Diabetics' Blood Sugar

...according to the report. In Type 1 diabetes, the islet cells of the pancreas are killed by the immune system, and the pancreas cannot produce insulin, which is needed to control blood-sugar levels. The condition can be roughly corrected by regular insulin injections throughout the day. Source-IANS...

Lives of Diabetics Transformed

...needed. Type 1 diabetes is characterized by the islet cells of the pancreas killed by the immune system, and the pancreas cannot produce insulin, which is needed to control blood-sugar levels. Although this condition can be roughly corrected by regular insulin injections throughout the day, night-tim...

Islet cell transplants for Type 1 Diabetes

A recent study reveals that islet cell transplantation may decrease the need of insu...nd Journal of Medicine. In this study, processed islet cells from dead donors were transplanted into 36 patients affected by this disease for around 27 yea...

MRI Can Monitor Transplanted Islets

...his loss and how it proceeds over time. Monitoring islet survival by noninvasive imaging could give us the ability to detect and measure rates of islet loss under a variety of conditions, which could help develop procedures leading to better therapeuti...

Gene May Regulate Cellular Aging

... University observed similar results in pancreatic islet cells and brain and blood stem cells. The results... on p16INK4a effects on the function of pancreatic islet cells. Islet cells are responsible for insulin production and secretion. Because p16INK4a stops canc...

Link between stem cells and aging

...ing Ink4a in young mice also reduced the number of islet cells hastening the aging of the mice albeit prematurely. The researchers were led to think that the protein protects against cancer by offsetting the reproduction of stem cells when they are old, a condition, which is known, to produce cancer....

Menin Gene Mutation made Insulin Secreting Cells to Proliferate

...nction resulted in the proliferation of pancreatic islet cells, which again affected blood sugar// regulati...ocrine organs, such as parathyroids and pancreatic islet cells. Normally, the menin protein has a tumor-suppressing or cell-proliferation-suppressing functio...

Shock Wave Therapy Increase The Risk Of Diabetes

...ly known risk of lithotripsy, which may affect the islet cells in the pancreas that make insulin. They believe the increased risk for hypertension may relate to scarring, which the treatment may cause to the kidneys and could alter the secretion of hormones centered in the kidneys like renin, which influen...

Islet cells producing insulin cultivated in the lab

... are believed to be good candidates for generating islet cells that can make insulin. The successful growth and characterization of these functional islet cells in the lab led to the conclusion that they may be suitable for treating individuals with Type ...

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