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Tag: "interferon" at medical news

Math Model Helps Identify Genes That Attack Hepatitis C Virus

...22,000 genes which are key for patient response to interferon treatment. "When we know which genes are responsible for fighting the viruses which attack our liver, we will be able to look for the medications which will activate these genes most favourably," Dr. Brodsky said. "In the specific case of hepatit...

Surgical Students Fail to Report Needle Stick Injuries

...xposed to HIV and HBV respectively. Treatment with interferon can eradicate HCV in more than 90% of cases of acute infection....

Researchers Identify Immune Dysfunction in Melanoma Patients

...ilure. Finding the disruption in the cancer cells' interferon response could help in the development of vaccines... immune cells of normal people. To verify that the interferon signaling was defective in people with melanoma, Critchley-Thorne isolated those cells and exposed t...

FDA: New Drug for Advance Kidney Cancer

...alone versus 7.3 months for those treated with the interferon alone. Progression-free survival (when the disease...es not get worse) increased from 3.1 months on the interferon alone arm to 5.5 months on the Torisel alone arm. The combination of Torisel and interferon did not ...

Pazopanib Shows Positive in Advanced Renal Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

...t human interleukin-2 (IL-2) and recombinant human interferon a-2b (IFN-a), either alone or in combination, have been widely used in patients with advanced disease. Although high-dose IL-2 has shown promise with durable complete remissions observed in 7% of patients, toxicity has limited its widespread use. L...

Three Cases of Hepatitis C Points Finger at One NYC Doctor

...al effective treatments for hepatitis C, including interferon and ribavirin. The officials refused to disclose the whereabouts of the doctor or whether he had the infection citing confidentiality statutes. They disclosed the fact the doctor has not been practicing....

New Test Helps Identify Hepatitis C Patients at High Risk of Developing Cirrhosis

...ung. Treatment includes weekly injections of alpha interferon along with the drug ribavirin, which can cost more than $30,000 per year and can cause flu-like symptoms, nausea, depression and other side effects. And only half of patients undergoing this therapy will be cured of the infection. Nearly 4 million ...

New Hepatitis C Drug Shows Promise

...and 4 are not as responsive to treatments based on interferon compared with the others. Interferon treatment for genotypes 1 and 4 takes nearly a year, whereas it takes just under 6 months to treat genotypes 2 and 3 with the drug. SRM/V...

Canandian Firm Announces Positive Results from Anti- Cervical Cancer Drug Trials

...d a clinically efficacious response to the topical interferon treatment in nearly half of the treated patients. In addition, the product demonstrated an excellent safety profile, with no significant adverse side-effects. Prof. Dr. Achim Schneider, a renowned expert in the field of cervical cancer and Directo...

Immunotherapy Does Not Prolong Life When Skin Cancer Spreads

...kinds of immunotherapy combined with chemotherapy, interferon and interleukin-2. Of the 11 studies that reported...ones were originally designed to do — for example, interferon is a natural antiviral agent, so the fact that it causes flu-like symptoms very commonly is not a su...

Immunotherapy Does Not Prolong Life When Skin Cancer Spreads

...kinds of immunotherapy combined with chemotherapy, interferon and interleukin-2. Of the 11 studies that reported...ones were originally designed to do — for example, interferon is a natural antiviral agent, so the fact that it causes flu-like symptoms very commonly is not a su...

A New Drug for Halting Metastatic Kidney Cancer

...f metastatic kidney cancer. A comparative study of interferon and// sunitinib treatments found that sunitinib is...se III of the research sunitinib was compared with interferon (a type of immunotherapy) in 750 patients with metastatic kidney cancer and it was shown that suniti...

Oral Flu Vaccine On The Horizon In Russia

...cine, called Korauban, is an immunostimulant gamma interferon inductor that is closely related to ordinary cellulose. The initial clinical candidate form will include antigens from three inactivated viruses (A1, A2, B). An undisclosed component, permitting 12-month tablet stability, will be used to develop a va...

'Hen Factories' To Synthesize Cancer Drugs

... hens were engineered to produce a type of human interferon that impairs viral replication. These proteins may then be extracted from the egg whites to be incorporated into the making of drugs. Insulin-related proteins have been mass-produced in bacteria. Many therapeutic proteins, like monoclonal antibodi...

No Pills Just Omelets

...ant melanoma, or skin cancer. Others produce human interferon b-1a, which can be used to stop viruses replicating in cells. AN...

New Biotech Drugs to Aid in Renal Cell Carcinoma Treatment

...iagnosed every year. The standard drugs used are interferon alfa and interleukin-2. Yet these drugs help in on...t of tumors, to 11 months as against 5 months with interferon alfa. This was tested on 375 cancer patients. In the case of sorafenib, half of 903 volunteers from...

Molecular ‘On/Off Switch’ Controls Immune Defenses Against Viruss

...tease to disrupt the signaling process, preventing interferon production and allowing viral replication. Just how RIG-I signaling is normally regulated, however, hadn’t been known. In the current study, UT Southwestern researchers found that RIG-I and LGP2 each contain a repressor domain, a sort of docking...

Soy’s Restorative Powers Confirme

...t therapies for MS involve injecting drugs such as interferon and copaxane, one goal is to develop an oral agent. BBIC could be given by pill daily. Source-urekalert PRI...

Making Headway Against Hepatitis C

...going study. Infergen is a highly potent type of interferon currently used for adult patients with chronic hepatitis C three times a week, Bacon says. This trial is expected to be completed in 2007. An estimated 3.9 million Americans have hepatitis C. About 250,000 who have been offered therapy are unrespon...

Study Unveils West Nile Virus Immune Evasion, Points to Vaccine Development

...ignaling activity of a protein receptor called the interferon alpha/beta receptor, or IFNAR, disrupting a cell’s...and spread. This highlights the integral role of interferon and IFNAR signaling in innate immunity. Dr. Gale said the mechanisms at work in the African strain...

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