Tag: "integrin" at medical news
Integrin helps healing process in cells
...ed two different proteins on skin cells. The first integrin
was called alpha (3) beta (1) and worked as a sort...ded tissue. These chemical messages and this first integrin
join forces, so to speak, and call on other cells from the bloodstream to move into the wounded area...
Tumors Targeted Naturally
...s group modified an agent known to bind tightly to integrin
and tethered it to alpha-Gal. When they mixed this...tead: They were killed regardless of the amount of integrin
they carried. Because target receptors on cancer cells usually reside on healthy cells, too - albe...
Penn Scientists Engineer Small Molecules to Probe Proteins Deep Inside Cell Membrane
... of these, the áIIba3 integrin, the most prominent integrin
on platelets, is involved in making platelet aggre...e platelet membrane it binds to the portion of the integrin
within the membrane, and subsequently perturbs another function in the clotting process downstream. ...
A New Target for Cancer Therapy-Integrin Alpha7 Molecule
Mutations in the cell adhesion molecule known as integrin
alpha 7 (integrin 7) lead to unchecked tumor cell ...onal Cancer Institute. These findings suggest that integrin
alpha7 represents an important new target for cancer therapy and prevention. Integrin alpha7 belong...
Protein Interaction is a Drug Target for Blood Clot Prevention
...involves the binding of many molecules to platelet integrin
alpha-IIb beta 3, and blockade of this binding is ... protein talin to alpha-IIb beta 3 is critical for integrin
activation in mice, and that selective disruption of the talinalpha-IIb beta 3 interaction protects ...
Fibrinogen may Inhibit Spinal Cord Regeneration
... inhibiting axonal growth by binding to the beta 3 integrin
receptor. This binding, in turn, induces the activation of another receptor on the neuronal cells, called the epidermal growth factor receptor. When the second receptor is activated, it inhibits the axonal growth. Other inhibitors have been identif...