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Tag: "inhibited" at medical news

Plastics in Common Household Items May Cause Fertility Defects

...Ob/Gyn, found that low doses of BPA in female rats inhibited estrogen induction in the brain. This can lead to learning impairment and, in old age, the onset of neurodegenerative disorders such as Alzheimer’s disease. Source-YALE University SM...

Chilli Extract may Stop Fat Cell Growth

... for 24, 48 and 72 hours, and found that capsaicin inhibited cell population growth in a dose and time dependen...t cells, as well as making body fat. "Capsaicin… inhibited lipid accumulation and the protein expression of PPAR?… These results demonstrate that capsaicin eff...

$1.5 Million Grant to Yale for Narcolepsy-Neurotransmitter Study

...arget, MCH neurons, were excited by hypocretin but inhibited by dynorphin. “This might suggest that the two neurotransmitters would simply cancel the actions of each other,” van den Pol said. “But, interestingly, in the continuing presence of both neurotransmitters, the inhibitory MCH cell response to dynorp...

Eat Berries, Prevent Colon Cancer

...ilbene also reduced colonic cell proliferation and inhibited certain genes involved in inflammation, both of which are considered colon cancer risk factors, the researchers say. Although researchers still do not know the exact cause of colon cancer, the disease has been linked to a high intake of saturated f...

A Newly Identified Immunosuppressive Protein in Rheumatoid Arthritis

...es. However, TNFá increased DcR3 expression in and inhibited Fas-induced apoptosis in RA FLS, but not in OA FLS. This study affirms DcR3 as an immunosuppressive agent that actually protects destructive rheumatoid synovial cells against death. "We suggest that DcR3 expressed in RA FLS is increased by TNFá, ma...

Marijuana Helps to Combat Lung Cancer

...study, the researchers first demonstrated that THC inhibited the growth and spread of cells from two different lung cancer cell lines and from patient lung tumors. Then they injected THC into mice that had been implanted with human lung cancer cells. After three weeks, tumors shrank by about 50 percent comp...

Peptide Found in Human Blood Inhibits 60 Strains of HIV, Study Says

A peptide found in human blood inhibited 60 strains of HIV from infecting cells in laboratory tests, according to a study published Thursday in the journal Cell//, the San Francisco Chronicle reports. Researchers found the peptide can inhibit HIV strains that have developed resistance to ex...

Green Tea Compound may Be a Therapy for Rheumatoid Arthritis

...und -- called epigallocatechin-3-gallate (EGCG) -- inhibited the production of several molecules in the immune ...iting the production of these molecules. EGCG also inhibited the production of prostaglandin E2, a hormone-like substance that causes inflammation in the joints....

Taiwan Researchers Claim Cancer Therapy Alternative

...bearing mice, treatment with the new compounds had inhibited tumor growth in 75 percent of the group, compared to 50 percent inhibition of tumor growths in mice treated with a-Galcer. Encouraged by the experiments, Dr. Chang Ya-jen, another researcher involved in the study, said the new compounds could be us...

Wheat Germ Extract Inhibits Breast Cancer in Study

...ar. Against the mouse ER+ cell line, MXT, Avemar inhibited growth by 50%, Aromasin by 46.7%, Tamoxifen by 34%....3%. Against the human ER+ cell line, T47T, Avemar inhibited growth by 49%, Tamoxifen 42%, Aromasin 25% and Arimidex 25%. Each agent was enhanced by 5 to 10% whe...

Anti-inflammatory Drugs Interact With Hormone Replacement Therapy

...ctive effect of hormone replacement therapy may be inhibited if women are taking a particular type of non-steroidal anti-inflammatory pain killer, report researchers led by Garret FitzGerald from University of Pennsylvania. The researchers examined the medical records of 1,673 women aged between 50 and 84 y...

Glucosamine-like Supplement Inhibits Multiple Sclerosis, Type 1 Diabetes

...e effective than the widely available glucosamine, inhibited the growth and function of abnormal T-cells that incorrectly direct the immune system to attack specific tissues in the body, such as brain myelin in MS and insulin-producing cells of the pancreas in diabetes. Study results appear on the online versi...

Sexual Fantasies Play an Important Role in Boosting Desire

...3 to 43, researchers have found that 32 percent of inhibited sexual desire in men is associated with low erotop... some sexual fantasies, while a 18 percent of such inhibited sexual desire in women is because of the increase of anxiety and the decrease of sexual fantasies. A...

Researchers Reverse Mental Retardation Symptoms in Mice

...ividuals. When the enzymatic activity of PAK was inhibited in the FXS mice, abnormalities in their spine number and structure-as well as the weaker electrical communication between their neurons-were reversed. The FXS mice exhibited symptoms similar to those in FXS patients. These included hyperactivity; p...

Ancient Viral Defense may Explain Susceptibility to HIV: Study

... against HIV, a modern-day retrovirus, the changes inhibited the protein's ability to stop PtERV1 and vice versa. This suggests that the antiviral gene may only be good at fighting off one virus at a time, according to the authors of the study in the journal Science. "TRIM5a may have served humans well milli...

Alzheimer's-associated Enzyme Linked to Seizures

...The resulting scarcity of membrane sodium channels inhibited the path of neuronal signals into and through the cells. "We have found a molecular pathway by which BACE can modulate the activity of sodium channels on neuronal cell membranes," Nature Cell Biology quoted Kovacs, as saying. Researchers suggested ...

Insecticide and Repellent Combo Effective in Eliminating Malarial Mosquitoes

...ixture had a lethal power and irritant effect that inhibited the mosquitoes from biting. Moreover, the mosquito...ndard repellent produced a synergistic effect that inhibited the mosquito from taking its blood feed. A synergistic effect was also observed with regard to the...

Flavonoids In Orange Juice Make It A Healthy Drink, Despite The Sugar

...ds in orange juice -- hesperetin and naringenin -- inhibited ROS generation by 52 percent and 77 percent, respectively. "Our data are relevant to patients with diabetes," said Dandona,"because stress from ROS and inflammation are increased significantlyin this population and may contribute to development ofa...

Researchers Find New Target for Anti-cancer Drugs

...s, no growth, which is exactly what we saw when we inhibited IL-6 in tumours, Counter said. Counter is encouraged that even though these findings are in cell culture and animal models, therapies based on targeting IL-6 in cancers driven by the ras oncogene could be tested in humans in the near future. A biot...

Cytokine IL6 as a New Chemotherapeutic Target for Ras-driven Cancers

...ncer, but time after time it defied attempts to be inhibited in the clinic. So we decided, why not go after something that you can make a drug against that Ras activates"" explains Dr. Counter. Dr. Counter and colleagues sought to identify other proteins that are secreted when Ras is activated, and evaluate ...

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