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Tag: "induced" at medical news

Strange Sex Life of Mole-rats may Provide Clues About Human Infertility

...them to show whos boss. We believe that the stress induced in the lower-ranking animals by this behaviour affects their fertility. There appears to be a total block to puberty in almost all the non-breeding mole-rats so that their hormones are kept down and their reproductive tracts are under-developed, Dr C...

Young Girls Turning to Speed for Losing Weight

...fad promoted by skinny models has resulted in drug induced look. 'The use of skinny models is promoting a drug-induced look as fashionable, something we should clamp down on, Taylor said....

Skin Cancer can Be Triggered by P53 Mutation

...nsitive to SCC formation and that D6 expression is induced in cells in close proximity to invasive SCC cells from human oral SCCs. In the absence of D6, skin inflammation sensitizes skin cells to tumor formation. In an accompanying commentary on these two studies, David Owens from Columbia University in Ne...

Role of MicroRNA in Cancer Suppression Identified

...in-vivo in mice as well as in cultured human cells induced the expression of a specific microRNA (miR-34a). Based on the likelihood that miR-34a could itself play a role in cellular apoptosis, researchers introduced miR-34a directly into human cancer cell lines to determine its impact on tumor cell behavior....

Insights into Acute Promyelocytic Leukemia

...observations suggest that dysregulated sumoylation induced by PML/RARA may contribute to altered gene expression and APL pathogenesis," explains Dr. de The. Taken together, results from these studies indicate that formation of higher-order homotetrameric complexes and recruitment of RXR are essential compo...

New Cancer Therapy in Clinical Trial

...totic defects. The researchers observed that TRAIL induced expression of two potent antiapoptotic molecules, Mcl-1 and cIAP2, and that c-Myc repressed both molecules. The researchers also discovered that the multikinase inhibitor sorafenib prevented TRAIL-mediated induction of Mcl-1 and cIAP2, and although...

Understanding HIV Interference With Infected Cell Division

...plex, is essential for the defect in cell division induced by Vpr. Further characterization of this protein complex as well as the elucidation of the mechanism by which it affects cell division may open new avenues for therapeutic intervention against HIV....

Novel Method of Adult Stem Cell Growth may Help to Treat Cornea Disorders

...ency of the cornea. Experiments on rabbits with induced limbic insufficiency showed that 60 per cent of the animals had recovered the corneal epithelium after the adult stem cells transplant. The corneal epithelium is the layer that is damaged with limbic insufficiency, a problem that results in opacit...

Scientists Demonstrate Heart Cell Replication in Mice

...researchers then moved to experiments in rats with induced heart attacks. In half the rats, a patch that had been incubated with periostin was placed over the infarct site, while the rest received Gelfoam only. Twelve weeks later, the treated patches were still releasing biologically-active periostin. The ...

Risk of Water Intoxication in Endurance Athletes

... of Boston marathon runners suffered from Exercise induced Hyponatremia (EAH), though most cases were mild. But since 1985, there have been at least eight documented fatalities from EAH related to long-distance events. The publics impression of the amount of water that is necessary to drink for good health...

Researchers Have Found the Role of Protein in Accelerating Breast Cancer Progression

...ding cells to remodel the tumour microenvironment, induced tumour angiogenesis, and increased the number of receptors for different markers of aggressive breast cancers. "Breast cancers progress through stages of increasing malignancy triggered by mutations that promote their growth," said Thomas Deuel, the...

Novel Method to Inhibit Prostate Cancer

...tests on cancerous prostate cells and on mice with induced prostate cancer. He found that this emulsion compound did not cause a hypersensitive reaction upon injection and even yielded better results than known drug treatments while inhibiting tumor growth substantially. Goldstein cautions that this inhibi...

Fishing for a Speedy Recovery After Chemotherapy or Marrow Transplant

...marks the first time stem-cell production has been induced by a small-molecule drug, says the studys senior author, Leonard Zon, MD, of the Childrens Hospital Boston Stem Cell Program and Division of Hematology/Oncology. Other studies, including one from Zon's own lab*, have identified ways of increasing for...

Indian Researcher Finds Human Urine Grows Better Fish Food

...on. "We believe this quick release of nutrients induced the fast reproduction in the plankton," said Jana. "We have not yet encountered any diseases or abnormalities in the zooplankton grown in tanks with human urine, but we are looking for hormone residues and antibiotics, just to be sure," he added. ...

Surface Logix Commences Phase 2a Clinical Trial of SLx-2101 in Raynaud's Disease

...ls, the candidate was highly potent and selective, induced rapid cellular and tissue response and provided an extended duration of action....

Diet for Autism

...and casein (protein found in dairy products), induced symptomatic improvements. But these claims are based on hope, lack factual basis and fall short of the required scientific evidence. Early studies did observe improvements in behavior and cognitive skills in autistic children who were placed o...

Soy Products a Double-edged Sword for Breast Cancer

... prior to puberty reduced the number of chemically induced mammary tumors. Other studies showed that estradiol, a primary human estrogen, spurs the growth of existing estrogen-dependent breast tumors. Helferich and colleagues demonstrated that like estradiol dietary genistein stimulates the growth of es...

Memory Loss Linked to Cognitive Disorders

... kept alive in specially constructed equipment and induced LTP by stimulating synapses with a rhythm known to be critical to memory formation. The brain slices were then sectioned and stained with one antibody that attaches to activated proteins involved with LTP and a second one that labels synapses. Newl...

Natural Pine Bark Extract Reduces Heart Failure Risk

...n of Pycnogenol reversed cardiovascular remodeling induced by L-NAME by blocking nitric oxide production, which leads to hypertension and finally cardiomyopathy," said Dr. Ronald Watson, professor in the Department of Nutritional Sciences at the University of Arizona and a lead researcher of the study. Aft...

Poisoned Workers of Hindustan Lever Demand Treatment

..., these children suffer from various known mercury induced illnesses such as brain disorders, heart disorders and congenital deformities. Appealing to the shareholders of HLL, the ex-workers said, Shareholders should not only be interested in the profits but also demand responsibility from the company. Ko...

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