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Tag: "inactivating" at medical news

Cancer gene mystery to be cracked!

...ll have scientists looking at nearly 10,000 genes, inactivating one at a time to find out precisely what they do and how they contribute to the development of cancer. They hope// that this effort will ultimately lead to the creation of new drugs that target rogue cancer-causing genes. Scientists will use a proce...

Neurobiology Provides Answers To Block Memory-Related Drug Cravings

...ated with cocaine use can be strikingly altered by inactivating a specific protein called ERK (extra cellular signal-regulated kinase) in the brains of animals. Especially significant is the finding that administering the inactivator compound immediately after recall of the cocaine-associated places also continue...

Protein Fragments Blocking Cures Alzheimer's Disease

...ble for causing Alzheimer's disease //that acts by inactivating the conversion of glucose into energy in Mitochondirial cells due to the protein fragments released from apoE. The apoE protein is found to be responsible for causing Alzheimer’s disease by not providing the glucose present in the brain to the neur...

How Does Leptin Work?

...f leptin's activities, ‘we devised a technique for inactivating STAT3 with pinpoint accuracy in the hypothalamus a...ptin,’ says Dr. Rossetti. ‘Our tool for rapidly inactivating STAT3 was a cell-permeable peptide (short protein) that we infused into specific areas of the hypoth...

Study Findings Could Help In Developing A Better Drug Delivery System

...uch components were removed from the process. By inactivating different cellular components, Yang discovered which components are essential to the disulfide reduction process. "It was surprising to learn that many other components of the cell, aside from those previously assumed to be responsible, were capabl...

Chronic Sinusitis Resulting From Weakene Immune System

... bacteria or fungi, binding to invading pathogens, inactivating them and making them easily disposed of. An earlier study published by the same team in the March-April issue of the American Journal of Rhinology also showed that sinus tissue from people with chronic sinusitis that resisted treatment had 30 times...

Scientists Make World Breakthrough

...hat a highly potent bacterial toxin kills cells by inactivating an essential component in the endoplasmic reticulum (ER). The latter is part of the cell that is essential for packaging newly-synthesized proteins. The toxin, called subtilase cytotoxin, is produced by certain strains of E. coli bacteria responsib...

"Tribbles" Protein Implicated in Leukemia

... the findings suggest that Tribbles induces AML by inactivating the C/EBP? protein. The results were published in this week’s issue of Cancer Cell. AML is a malignancy that arises in white blood cells and develops when there is a defect in immature immune cells in the bone marrow. In AML, the uncontrolled, exag...

Limb Regeneration Exists Innately In All Vertebrates – Says Researc

...ks that can't normally replace missing limbs while inactivating it in animals known to be able to regenerate their limbs (frogs, zebrafish, and salamanders) shuts down their ability to replace missing legs and tails. "In this simple experiment, we removed part of the chick embryo's wing, activated Wnt signaling...

Effects Of Age-related Vascular Diseases Can Be Reduced By Inactivating TNFa

... hope for significantly reducing vascular aging by inactivating TNFa, which has been linked to blood vessel dysfunction and cell death. Age-related vascular diseases, including high blood pressure, heart attack and stroke, occur naturally, even in otherwise healthy individuals. Advanced age is also associated w...

Researchers Discover Potential Targets To Reduce Risk Of Stem Cell Transplants

...y engineered mice, the researchers have shown that inactivating the SHIP gene for just one week protects transplant recipients from acute GvHD. This protection is seen even when the graft contains extra immune cells to help the graft "take" or when the graft cells are completely mismatched to the recipient. The f...

Brain Tumor Drug in Frogs A New Report

... binds to its surface before invading the cell and inactivating the RNA it contains, causing the tumour to die. In new research published in the Journal of Molecular Biology, scientists from the University of Bath (UK) and Alfacell Corporation (USA) describe the first complete analysis of the structural and che...

Mayo Clinic Physicians Have Adapted Real-time 3-D Ultrasound Imaging Devices

...as anesthesia is released and surrounds the nerve, inactivating it, Dr. Feinglass says. No one thought peripheral regional blocks could be done in real-time 3-D, and we believe we are the first in the world to really do it. Most people are familiar with traditional 3-D ultrasound probes that can see a growing fe...

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