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Tag: "immunoglobulin" at medical news

Boffins Identify Molecule That Might Treat Food Allergy

...n as if it was harmful. The immune system produces immunoglobulin E (IgE) antibodies, which normally help the body fight parasites. In the most severe cases individuals can suffer life-threatening reactions, including anaphylactic shock. The study was conducted by a team of researchers led by Dr Claudio Nicolett...

Potential Target for Allergy Therapy

...n as if it was harmful. The immune system produces immunoglobulin E (IgE) antibodies, which normally help the body fight parasites. In the most severe cases individuals can suffer life-threatening reactions, including anaphylactic shock. In previous research, Dr Nicoletti found that special types of white blood c...

Scientists Develop Method to Track Immune System Enzyme in Live Animals

...es random mutations and recombination in the cells immunoglobulin (antibody) genes. For the most part, these genetic changes are beneficial because they enable B lymphocytes to attack and stop the invader. In some cases, however, AID-dependent alterations in the genetic material of B cells can also lead to unwanted...

Hay Fever Can Send Work Productivity Down the Drain

...erwent a blood test that evaluates the reaction of immunoglobulin E (IgE) to specific allergens, such as pollen from grass and trees. IgE is an antibody that triggers allergic reactions. In a previous study, Szeinbach found that the ImmunoCAP IgE blood test was more accurate in diagnosing allergies when compared to...

Lactococcus Strain may Offer End to Food Allergies

...nificantly, while blood levels of antigen-specific immunoglobulin E (IgE) - an antibody subclass capable of initiati...educed. Moreover, production of antigen-specific immunoglobulin A (IgA) in the gut "These results suggest that a microorganism bioengineered to deliver IL-10 in ...

Inflammation can Lead to Cancer

...ay. Part of the receptor for the antibody known as immunoglobulin appears to be involved, Coussens said. The good ...d no likelihood that periodic booster shots of the immunoglobulin antibody, or even blood transfusions from someone with precancerous tissue could trigger cancer prog...

Drug Meant to Heal Turns ‘heel’ and Hars

...mitted "illegal behavior" in the production of its immunoglobulin drug and that users had tested positive to "Hepati...experts as saying that the plasma used to make the immunoglobulin drug might have contained either the hepatitis C virus or its antibodies. It would take two to ei...

Anti-rejection Therapy a Boon for Patients With "anti-donor" Antibody Levels

...pioneered in the late 1980s the use of intravenous immunoglobulin (IVIG) as a way to reduce organ rejection among highly sensitized individuals. After undergoing years of experiments and clinical trials, IVIG became a fully accepted, Medicare-approved therapy in 2004 when it was found effective in a multi-center st...

Therapy Modulates Highly Sensitized Immune System to Let Mother Give Kidney to Daughter

...pioneered in the late 1980s the use of intravenous immunoglobulin (IVIG) as a way to reduce organ rejection among highly sensitized individuals. After undergoing years of experiments and clinical trials, IVIG became a fully accepted, Medicare-approved therapy in 2004 when it was found effective in a multi-center st...

A Collaboration to Find New Tools to Fight Leukemia

...ound in CLL cells), IgVH (mutational status of the immunoglobulin gene occurring in CLL patients), and FISH panel assessments (fluorescent probes on the chromosomes to determine common recurring genetic mutations in CLL). The majority of the patients were in high-risk categories; they had significant disease progre...

Orissa Confirms First Dengue Case

...more pathological tests," said Jena. "Since the immunoglobulin (IG) test facility is not available in the state, we sent his blood sample to the New Delhi-based Dr. Lal Path Labs. The report reached us on Sunday and confirmed that he is suffering from dengue," he added. Jena said this was the first case of den...

Cure for food allergies is less than a decade away

...rreaction of the cells of the immune system called immunoglobulin E (IgE) to protein molecules that are normally harmless leads to an allergic reaction. These protein molecules are called allergens and are present in cats, horses, nuts, milk and pollen. In Britain, some form of allergy affects 30% of adults and 4...

Single Sugar Enables Antibody to Treat Inflammation

... to be an apparent contradiction.// Intravenous immunoglobulin (IVIG) is a complex mixture of IgG antibodies made from human plasma that contains the pooled antibodies from thousands of people, and is only FDA-approved to treat a few assorted conditions; nonetheless, practitioners have used it off-label with var...

Insufficent Anti-inflammatoy Proteins Leads to Chronic Pain

...nts. The 40 pain patients had received intravenous immunoglobulin (IVIG) as a novel treatment for pain that was not responsive to standard therapy, while the additional 15 patients did not receive this treatment. Blood samples were analyzed for both pro-inflammatory and anti-inflammatory cytokines. In addition, pat...

Protein Behind Food Allergies Identified

...g since not every patient has detectable levels of immunoglobulin E (IgE) in their serum, especially patients with delayed allergies. A number of reliable testing methods exist for food and other allergies, including skin tests and serum IgE tests; however, they may not accurately diagnose the allergies. The ...

Infants Need to Be Vaccinated For Hepatitis B

...l, have been researched with regard to hepatitis B immunoglobulin and hepatitis B vaccines for the hepatitis B surfa...long with immunoglobulin. The combination with the immunoglobulin was seen to be the better and more effective alternative. Further research however is required with ...

Possible Viral Cause Of Kawasaki Disease Identified

...y and colleagues showed that synthetic versions of immunoglobulin A antibodies made by children who developed Kawasaki disease bind, or attach, to spheroid structures in the bronchi, the breathing tubes in the lung. These antibodies are likely produced to combat the infectious cause of the disease. In the current ...

Researchers Feel The Need For Standards Of Practice In Immunoglobulin Therapy

...a requirement for having a standard of practice in immunoglobulin therapy. A review article published in the July/A... in correctly dosing and administering intravenous immunoglobulin (IVIG) as replacement therapy in patients with primary immunodeficiency (PI) disorders, who do not p...

Different Types Of Multiple Sclerosis May Be Treated Differently

... pattern II MS lesions contain large quantities of immunoglobulin (proteins that serve as antibodies) and complement activation (the ability to combine with antibodies to destroy tissue) experienced moderate to marked improvement after treatment with plasma exchange. These patients experienced major gains in cerebr...

Gene responsible for immune deficiency discovered

...ferent form of immune deficiency conditions called immunoglobulin A (IgA) deficiency and Common Variable Immunodeficiency (CVID). Immune deficiency syndrome may be hereditary or acquired. Hereditary or primary immune deficiency diseases are generally caused by defects in the cells and tissues that are responsible ...

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