Stem Cell Treatment may Prolong Lives of Children With Brittle Bone Disease
...imperfecta (OI). The genetic defect, detected in human foetuses by DNA testing or ultrasound, disrupts co...e college, the researchers studied mouse models of human type III osteogenesis imperfecta. They injected human foetal mesenchymal stem cells through the wall...Common Environmental Chemicals Hamper Ovary Development in Foetus
...er, while the treatment group was grazing digested human sewage sludge fields, before and during pregnancy....y 110 of gestation, the equivalent of week 27 in a human pregnancy, and found that the ovaries from the foetuses where the mother was grazing the sewage slud...Genetic Mutation That Makes Common Cancers Resistant to Drugs Identified
...g the most commonly activated cellular pathways in human cancers and members of this pathway are among the ... of direct mutation of AKT1 in clinical samples of human cancer tumours. "This discovery is a seminal finding in cancer biology that confirms AKT1 as an o...Great Lakes Fish in Canada Heavily Polluted
..., PCBs, and methyl mercury that they are unfit for human consumption, says the report. Health effects of ...kes continue to be polluted to such an extent that human health is threatened, it said, calling for steps to significantly reduce pollution emissions in the ......le in their shape and brain-invasive behavior from human oligodendrogliomas. The combination also activated the Akt pathway, which PDGFB does not induce by itself. Combined with their earlier findings, this led the team to hypothesize that IGFBP2 activates the Akt pathway, which they confirmed in subsequ...Insight Into Neural Stem Cells Has Implications For Designing Therapies
... lab has identified neural stem cells in the adult human brain, but it is not known if these cells are heterogeneous. If human brains show a similar regionalization of stem cells, it might also be possible, says Alvarez-Buylla,...France Steps Up Vigilance After Bird Flu Outbreak
... pandemic as there has not been, for the moment, a human contamination from the H5N1 virus," Health Minister Roselyne Bachelot said. But she added "we must be vigilant as the great flu epidemic that followed the war of 1914, the Spanish flu" came from a strain of bird flu. Scientists believe a strain r...Skin Cancer can Be Triggered by P53 Mutation
...noma skin cancer, which is the most common type of human malignancy with over 1 million new cases in the US...thors show that certain p53 mutations occurring in human SCCs demonstrate gain-of-function properties that accelerate the frequency and progression of malign...New "second-line" AIDS Drug Shows Promise in Trials
...tance problems is a "viral load" -- a count of the human immunodeficiency virus (HIV) which causes AIDS) -- to below 50 viruses per millilitre of blood. At the 24-week point in the two trials, 56 and 62 percent of patients in the etravirine group had achieved this goal, The Lancet paper says. Among the "...EpiCept Accelerates Development of Phase I Clinical Study for Cancer
... multi-drug resistant cell lines. Murine models of human tumor xenografts demonstrated EPC2407 inhibits gro...pound is currently being evaluated in two Phase II human clinical trials, one in patients with primary brain cancer and the other in brain metastases due to ...Scientists Discover Key to Manipulating Fat
... in Nature Medicine on July 1, could revolutionize human cosmetic surgery and treatment of diseases associated with human obesity. Investigators say these findings may also, over the long-term, lead to better control of m...Scientists Find Single Circuit Channeling Depression in Rats
...th, rat brains show similar depression symptoms to human ones and react to anti-depression medicines in the...ough the brain could be readjusted with the use of human drugs against depression -- suggesting the existence of a specific circuit for the condition. Acco...US Baby Dies of Salmonella from Pet Turtle
...the report An estimated 1.4 million nontyphoidal human Salmonella infections occur each year, causing about 15,000 hospitalizations and 400 deaths, it said.......so looked at how genes were being expressed within human blood cells. The U-M was one of the major data analysis sites. The team confirmed its findings by analyzing the genetic makeup of more than 2,000 children from Germany and more than 3,000 subjects from the United Kingdom born in 1958 and monitored u...Snack Foods Fortified With Fiber
...h include Koushik Adhikari, assistant professor of human nutrition; Tom Herald, professor of food science; and Ron Madl, director of K-State's Bioprocessing and Industrial Value Added Program...Fibrinogen may Inhibit Spinal Cord Regeneration
...ego (UCSD) School of Medicine, may explain why the human body is unable to repair itself after most spinal cord injuries. The study, led by Katerina Akassoglou, Ph.D., assistant professor in UCSDs Department of Pharmacology, is the first evidence that when blood leaks into the nervous system, the blood pr...Role of MicroRNA in Cancer Suppression Identified
...tion of p53 in-vivo in mice as well as in cultured human cells induced the expression of a specific microRN...osis, researchers introduced miR-34a directly into human cancer cell lines to determine its impact on tumor cell behavior. The results clearly demonstrated t...Gadrasil Could Prove Effective in Men too
...ively fights off two of the most common strains of human papilloma virus, the most prevalent STD in modern society. In North America, HPV is said to infect half of all sexually active women between 18 and 22. In most women, HPV clears up on its own but for some, the infection persists and can lead a coup...Tenaxis Medical Inc. Announces First Human Use of Vascular Sealant
...valently binds to proteins in both the sealant and human tissue. "I am extremely proud of the progress the team has achieved in developing a meaningful new generation of vascular sealants," said Ronald Dieck, President and CEO of Tenaxis Medical, Inc. "This is the first step in a comprehensive clinical pro...Cancer Risk is High Among HIV/AIDS and Kidney Transplant Patients
...in both these populations, cancers associated with human papilloma virus, from cervical cancer to cancers of the mouth, penis and anus were significantly increased. One of the three cancers that were already linked with HIV is Kaposis sarcoma. In HIV population, there was a 3,640-fold increased likelihoo...