Gene Mutation May Influence Age at Onset of Parkinson's Disease
... researchers had not previously determined whether heterozygotes were at increased risk for Parkinson's disease. P...blings shared the same version of the parkin gene, heterozygotes developed Parkinson's disease an average of 11.7 years earlier than those with no mutations, and tho...New Diagnostic Tool Uncovered Gene Expression Patterns in Recessive Genetic Disorders
... normal, although some reports have suggested that heterozygotes may have an increased risk of cancer. Using microarray technology, which simultaneously ascertains the expression patterns of thousands of genes, Cheung and Ewens discovered that heterozygous carriers of NBS exhibited distinct gene expression patte...