Targeting the Adrenal Gland Could Be Key Against Heart Failure
... B. Liggett, M.D., director of the cardiopulmonary genomics program at the University of Maryland School of Medicine, who has written an accompanying editorial. “Despite our best efforts, about half of all heart failure patients die within five years of diagnosis, so clearly something new is needed. These r...Novel Test Identifies Leukemia Patients Likely to Respond to New Therapy
...t expressed. The researchers used state-of-the-art genomics technology to analyze a panel of diffuse large B cell lymphoma cell lines. They found a set of 485 BCL6-controlled genes and confirmed that all lymphomas with the BCL6 signature are killed by BPI while lymphomas without the signature are resistant t...Diagnosis Of Sjogren's Syndrome Possible Using Saliva
...thy subjects. Using cutting-edge proteomics and genomics technologies, they searched globally for markers in saliva from SS patients and healthy people, and found that saliva, especially whole saliva (that is, the combined saliva in the mouth, vs. saliva from the individual salivary glands), is informative...Boffins Find Link Between Common Sleep Disorder and Hypertension
... colleagues at deCODE Genetics, Inc., an Icelandic genomics company, and Icelandic physicians at Landspitali in Reykjavik. The research team recruited 900 Icelanders for the study. Participants provided clinical information and the number of PLMs they experienced per hour of sleep over a period of two to five...Intensive Psychotherapy Provides Helping Hand in Borderline Personality Disorder.
...velopment of basic studies in the neuroscience and genomics of BPD.The study was supported, in part, by the Borderline Personality Disorder Research Foundation and the Personality Disorders Institute at the Department of Psychiatry, Weill College of Medicine, Cornell University....Genetic Variation is Linked to Substantial Risk in Heart Attack
.... The research project was led by the Icelandic genomics company deCODE Genetics, along with U.S. researchers at Emory University School of Medicine, Duke University, and the University of Pennsylvania. Myocardial infarction is the death of heart tissue that results when the blood supply to the heart is..."Decryption" of Enzyme's Functions Paves Way for Future Drug Discovery
...ructure was determined as a part of the structural genomics project, a large-scale, worldwide effort to determine the structures of enzymes and receptors. As the scientists knew the nature of the substrate, they went on to discover that the enzyme works in a previously uncharacterised metabolic pathway in ...Prof Samir K Brahmachari, Dr MRS Rao Jointly Win Bio-medical Research Award
...e had made fundamental discoveries in the areas of genomics that led others to develop approaches for cancer therapeutics. His most significant contribution is in the identification of three novel genes of SARS virus. Dr. Rao, President of the Jawaharlal Nehru Centre for Advanced Scientific Research at Ba...First Bacterial Genome Transplantation Changing One Species to Another
...is one of the key proof of principles in synthetic genomics that will allow us to realize the ultimate goal of...tted to this research as we believe that synthetic genomics holds great promise in helping to solve issues like climate change and in developing new sources of ......ructure was determined as a part of the structural genomics project, a large-scale, worldwide effort to determine the structures of enzymes and receptors. With the nature of the substrate in hand, the scientists went on to discover that the enzyme works in a previously uncharacterized metabolic pathway in b...