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Tag: "genome" at medical news

Discovery in Male Mice Gives Hope in Providing Clues to Find Infertility in Men

...esearchers randomly induced mutations in the mouse genome and then looked for infertility in the resulting mice. They then analyzed the DNA of the sterile males and identified the allele that caused the infertility. While most studies on the genetics of fertility stem from analyses of mice that have had a c...

UK Scientists to Reveal Genetic Secrets Behind Serious Illnesses

... play a part but we haven't found the parts of the genome involved." However, some scientists have pointed out that there are other, as yet undiscovered, genes involved in obesity, casting doubt on the usefulness of a test aimed at FTO alone. Obesity is a complex disorder and there is no evidence from t...

Scientists Identify Genes Activated During Learning and Memory

... search the letters of code that make up the human genome to find just those genes activated by CREB and zif268. They specifically searched almost 20,000 genes to find those that CREB and zif268 bind to. This work, conducted by Carnegie Mellon undergraduate Andreas Pfenning and supervised by Assistant Profe...

Researchers Identify New Genetic Risk Factors for Type 2 Diabetes

...hnologies generated by the sequencing of the human genome and subsequent mapping of common human genetic var...can serve as a strong pointer to the region of the genome where the genetic risk factor resides. However, the first variants detected may not themselves direc...

Genetic Flaws Leads to Diabetes

...lth Institute. The results show the power of the genome wide association in finding genetic variation in the disease. The three group had different groups of participants with or with out the type 2 diabetes. They were checked using microchip array technique to scan and evaluate their genome. With the...

DBT And IAVI Forge Partnership To Develop “Next Generation” Vaccine Candidats

...disease resistance, nutritional quality, silk-worm genome analysis, molecular biology of human genetic disorders, brain research, plant genome research, development, validation and commercialisation of diagnostic kits and vaccines for communic...

Gene Mutations Leave Caucasians Prone To Heart Diseases And Diabetes

...Since the landmark completion of mapping the human genome in 2003, scientists have been able to sniff out vital genes from virtually, millions of them. The two studies, using 40,000 people, found the same thing -a stretch of DNA called 9q21 carried certain mutations in people with heart disease. Scientists ...

Scientists Discover Rare ‘gene-for-gene’ Interaction That Helps Bacteria Kill Their Hot

...earch is that we have been able to study the whole genome of the bacteria to work out how it kills its host,” said Professor Stuart Reynolds from the University of Bath. “People studying diseases think that the kind of gene-for-gene interaction between pathogen and host that we have found is quite common,...

HIV Drug Resistance can Be Identified by Genome Sequencing

...searcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations. Kozal, associate professor of medicine at Yale and senior author of the retrospective study that used samples from an earlier clinical trial, presented the findings today at the 16th ...

Parkinsons Disease can Be Predicted by Metabolic Pathway

...ed their findings using data from additional whole genome DNA and RNA variation datasets for Parkinsons dise... from a dataset of DNA variations across the whole genome has been employed to study the joint effects of a subset of DNA variations within a defined biologic...

Landmark Study Prompts Rethink of Genetic Code

... detailed probe yet into the workings of the human genome has led scientists to conclude that a cornerstone ...s of the Atlantic, takes a small percentage of the genome to pieces to draw up a "parts list," identifying the biological role of every component. For the i...

Researchers Cracking the Human Genome Function

... have completed the understanding of how the human genome functions . While previous studies of the human genome have focused mainly on genes, this study provides insight into the non-gene sequences making up the ...

Vaccines On Your Plate

... producing cholera toxin, into a rice plant, whose genome has recently been mapped. The plants produced the toxin and when the rice grains were fed to mice they provoked immunity from the diarrhea-causing bacterium. The bacteria that cause cholera infect the gut and causes bloody stools. Nearly 200,000 ca...

Genetic Risk Factor for Coeliac Disease Identified.

...have enabled us to scan variation across the human genome in large numbers of people for association to dise...e Sanger Institute made available to the study the genome data on 1500 British individuals used as controls (i.e without coeliac disease). The consortium stud...

Largest Ever Study of Genetics Behind Common Diseases Published

...on diseases. Many genes were found in areas of the genome that were not previously thought to have been rela...ely scan most of the common variation in the human genome to look for variants associated with diseases. This approach will undoubtedly herald major advances ...

GAB2-A New Alzheimers Gene Identified

... sufficient number of letters throughout the human genome to provide a clearer picture of how life works and ultimately allow better clinical management of patients, said Dr. Dietrich Stephan, Director of TGens Neurogenomics Division and the papers senior author, These new, robust tools may eventually allow...

Mouse Model Points to Strategy for Treating Rare Muscle Disease & Kidney Disorders

...hnologies generated by the sequencing of the human genome are being used to uncover new strategies for treating genetic human disease, said NHGRI Director Francis S. Collins, M.D., Ph.D. This work also underscores the value of animal models in learning more about the pathways involved in human disease and h...

Scientists Identify Four Genes That Raise the Risk of Breast Cancer

... but we have been able to search two thirds of the genome in one go," Times Online quoted him as saying. "Rather than fish for new genes one at a time with a rod and line, we have trawled the pool. This is not only a more efficient approach, it gets round the bias of previous studies in which scientists o...

Genome of Botulism Bacterium Revealed

...mounts of the toxin, is used medically. Now, the genome of the organism is exposed. The report in Genome R...ifficile - the Cdiff superbug - C. botulinum has a genome that is remarkable because it is so stable, "commented Dr Mohammed Sebaihia, lead author on the pape...

UK Scientists Identify Gene Mutations That Trigger Breast Cancer

...ery is that it brings the day closer when anyone's genome - the entire DNA blueprint - can be screened for t...cientists used "DNA chips" to screen each person's genome for genetic variations that were found to be strongly linked with breast cancer. Small variations in...

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