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Tag: "genetic" at medical news

Combining NSAIDs With Chemotherapy May Improve Cancer Therapy

...re the cell synthesizes new DNA and replicates its genetic material. "The finding that the cell killing effect takes place in S phase is particularly exciting because one of the standard therapies for most cancers -- chemotherapy -- often has its maximal effect at that stage of the cell cycle," Trask said...

DNA-damage Test Could Aid Drug Development

...oped a cell culture test for assessing a compounds genetic toxicity that may prove dramatically cheaper than existing animal tests. This assay would allow genetic toxicity to be examined far earlier in the drug development process, making it much more efficient. ...

Pediatric Cancer Stem Cell Identified

... cancer stem cell and the evolutionarily conserved genetic programs underlying self-renewal in ERMS will like...tify both an ERMS tumor-cell-of-origin and a novel genetic signature that underlies ERMS progression in zebrafish and human patients. Cancer stem cells make up...

Protein Folds Research Offers Insight into Metabolic Evolution

...am used data from two international collections of genetic and proteomic information: the metabolic pathways ...f fundamental importance undisputedly encoded in a genetic core that can be traced back to the universal ancestor of the three super kingdoms of life, the auth...

Genetic Marker Linked to Aggressive Prostate Cancer

...archers have discovered that a recently identified genetic marker for prostate cancer is linked to a highly a...esearchers said. Knowing which patients carry this genetic marker also will guide doctors in how they treat the cancer. The Northwestern study showed a stron...

Toxic Substance in House Dust may Reduce Eczema Risks in Early Life

...ys. The researchers also plan to examine whether genetic predisposition modifies a childs responses to environmental triggers....

Researchers Use Gene Therapy to Restore Eyesight in Blind Mice

...s virus to provide corrective genes to mice with a genetic impairment that blocks their vision. Researchers measured the electrical activity in the retinas of mice for two months after the administering the gene therapy injection into the subretinal space of the rodents. Scientists found that 19 out of t...

Climate Change Threatening to Wipe Out Wild Relatives of Key Crops

...d up losing a significant amount of these critical genetic resources at precisely the time they are most needed to maintain agricultural production, added Annie Lane, the coordinator of a global project on crop wild relatives led by Bioversity International. The results of the study were announced on Inte...

Regular Smokers are at the Risk of Developing Depression

...nd the fouth says that there are shared underlying genetic factors explaining this co-morbidity. This stud...nally, it was possible to explore potential shared genetic influences underlying the association. The results suggest that first, persistent chronic cigarett...

Rise in Cigarette Use may Elucidate Asthma Epidemic in Children

...oost the severity of their asthma symptoms. Both genetic and environmental risk factors for asthma have been recognized, noted Dr. Goodwin. Internationally, six studies have shown environment tobacco smoke to be a risk factor of incident asthma. The risk for the growth of childhood asthma was 2.5 times gre...

New DNA Tests Advances Treatment of Lysosomal Storage Diseases

...fied laboratory directors and four board-certified genetic counselors. The prevalence of lysosomal storage ...tor skills. Type I Gaucher disease was the first genetic disorder that could be treated effectively with enzyme replacement therapy (ERT). Over the past deca...

'Star Trek'-type Scanning may Help Reveal Genetic Activity of Tumors

... scans, may enable doctors to discern most of the genetic activity of a tumor. They say that such an information may lead to diagnosing and treating patients individually, based on the unique characteristics of their disease. "Potentially in the future one can use imaging to directly reveal multiple fea...

Exercise can Slow Down the Aging Process in Elderly People

... older adults. Nevertheless, exercise upturned the genetic fingerprint back to levels similar of younger adul...sidered to find out if resistance training has any genetic impact on other types of human tissue, such as those that comprise organs. Researchers also want to ...

Intake of too Much Salt Could Lead to Stomach Ulcer

...ciences in the USA found high levels of salt cause genetic changes in the bacterium and make it more powerful, reported online edition of Daily Mail. The team of scientists headed by Hanan Gancz said the bacterium might also increase the risk of gastric cancer. "It was known that people who ate a high-sa...

Genes Associated With Limb Development is More Primitive Than Believed

...ns of a basal actinopterygian fish, shows that the genetic and developmental toolkit that builds limbs with f...itive bony fish, the paddlefish. We found that the genetic capability seen in tetrapods to build limbs is present in even more primitive fish," said Dr. Davis....

Exposure to Smoking in Prenatal Stage Increases ADHD Risk in Children

...19 years, so as to assess the relationship between genetic variations, prenatal substance exposures, and ADHD sub-types. br> "When genetic factors are combined with prenatal cigarette smoke exposure, the ADHD risk rises very significantly....

Gene Discovery Lays Groundwork for Targeted Therapies for Endometrial Cancer

...ommon gynecologic cancer in the United States. The genetic changes result in uncontrolled cell division, a hallmark of cancer. Drugs already in clinical trials inhibit FGFR2 function and could potentially lead to new treatments for endometrial cancers, according to the researchers. Nearly 40,000 women are ...

$5M Gift Will Attack Lou Gehrig's Disease

...Among the weapons they will deploy against ALS are genetic tools to keep nerve cells from dying, new ways of ... and her team have already succeeded in creating a genetic snippet that can encourage cells to increase the number of times their genetic machinery reads the g...

Drink, Binge and the Genetic Link

...pe treatment protocols by studying the causative genetic variants. Prevention and treatment of smoking and other abusive substances can also be improvised. This will also help the affected individuals to make informed choices based on recommendations. Although these findings are part of the inevitable evol...

Researcher Studying Disease That Cripples Newborns

...onic dystrophy (CDM1), a progressive and crippling genetic disorder. Although doctors know that babies inherit CDM1 from their mother and prenatal tests are available, many children are not diagnosed until they are born. In these instances, mothers dont know that they have type 1 myotonic dystrophy (DM1) ...

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