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Tag: "genetic" at medical news

New Mouse Model to Aid in Cancer-causing Genes Hunt

...c cancers, and multiple myeloma. They found that genetic instability in the mouse cancer cells resulted in ... cancer. "We found a rather striking overlap of genetic alterations in the mouse and human cancers, which should greatly help us sort out genetic events tha...

New Gene Therapy may Be Helpful in Eliminating Arthritis Pain

... develop osteoarthritis like humans, with the same genetic predisposition that makes some people more likely to develop the disease. The researchers used gene therapy to increase the number of receptors, which accept naturally occurring painkillers called opioids, on the surfaces of nerve cells that carry...

Global Heartbeat Control Suggests Therapy for Beating Heart Failure

...y, a feat depending on the coordination of several genetic programs. Now, researchers report in the May issue of Cell Metabolism, a publication of Cell Press, that two closely related receptors can act together or separately to pull all of the strings. Drugs that influence these newfound global orchestrat...

UK Scientists Identify Gene Mutations That Trigger Breast Cancer

...outine breast screening now begins. Unlike other genetic variations associated with familial breast cancer,...position. However, the wider significance of the genetic discovery is that it brings the day closer when anyone's genome - the entire DNA blueprint - can be ...

Scientist Found New Mechanism for Brain Learning

...gs that would help create the same effects without genetic manipulation. The study also showed nerve-cell firings in the hippocampus, an area of the brain associated with learning. Hippocampus slices from the knock-out mice responded much more strongly to an electrical stimulation, supporting the finding t...

Brain Cells Activity: New Treatment Target for Psychiatric Diseases

...and that normal synapse development is impaired by genetic defects in neuregulin-1 and ErbB4 signaling. The result is impaired function of the excitatory neurotransmitter, glutamate. Now he wants to study disease processes in a neuregulin-1/ErbB4 knockout mouse and learn more about how neuregulin-1 mediate...

Genome of Botulism Bacterium Revealed

...clostridia has been hampered by the lack of a good genetic system. Professor Nigel Minton, Professor of Applied Molecular Microbiology at the University of Nottingham, has developed new methods to knock out genes in clostridia. "Even after decades of research, only a handful of mutants had been made in clo...

Fecal Bacteria, a Source of Contamination

...m Creek watershed. The source-tracking tools use genetic material from bacteria collected in water and sedi...to determine their source, either by comparing the genetic material with that of known fecal bacteria sources, or by looking for a marker within the genetic ma...

HIV Spreading Rapidly Among Gay Men in Hong Kong

...erers has revealed a cluster of cases with similar genetic sequencing which has risen from 34 to 53 cases since October last year. Department of Health expert Wong Ka-hing urged people with a history of unprotected sex to have HIV tests, saying the findings suggested "rapid local HIV transmission" among ga...

Nervous Systems of Insects may Offer Clues on Neurodegenerative Diseases

...neticist, I thought we could use the sophisticated genetic approaches available in the fruit fly to understand this. This led to a second research project, which involves studying mutant flies that lack the ability to add the terminal sugar, sialic acid, to specific proteins of the central nervous system. ...

Genes may Have a Role in Learning "tonal Languages"

... the first obvious connection between language and genetic variation. Slight pronunciation differences in tonal languages can fundamentally alter the meaning of words, which may be one of the reasons why these languages are so tough to learn for speakers of non-tonal languages such as English. By means ...

Researchers Identify the Gene Mutation That Raises Breast Cancer Risk

...h factor receptor 2 (FGFR2), is the most important genetic risk factor for breast cancer identified in about ...chers specifically looked for small changes in the genetic code known as single nucleotide polymorphisms (SNPs) that are associated with breast cancer. They ...

Genetic Code That Helps Kill Colon Cancer Cells Identified

...sts at Johns Hopkins have identified a tiny bit of genetic code, which helps the p53 gene to kill the colon cancer cells. The genetic code is called miR-34a, a microRNA which participates in p53's uncanny ability to kill cells that ar...

Gene Mutation That Increases the Risk of Chronic Lymphocytic Leukaemia Found

...t of CLL cases are sporadic, that is, they have no genetic component. As part of the study, researchers id...findings show that it's important to look for both genetic and epigenetic alterations when identifying problem genes," Plass said. The findings of the study ...

Genetic Testing Helping Cancer Survivors Fight For Their Loved Ones

...elves and their families from the disease through genetic testing and hereditary cancer risk assessment. Gen...r of cancer patients are choosing to be tested for genetic abnormalities that significantly increase the risk of getting the disease in a different form. "Wi...

AutoGenomics Addresses TB Crisis With a Genetic Drug Resistance Test

...e passengers who were exposed. The INFINITI MTB DR genetic test has been designed to identify the presence of multi- drug resistant TB by directly detecting the resistance gene in the mycobacteria". MDR-TB (Multidrug Resistant TB) is a type of mycobacterium tuberculosis that is resistant to at least the tw...

Mouse Model Points to Strategy for Treating Rare Muscle Disease & Kidney Disorders

... being used to uncover new strategies for treating genetic human disease, said NHGRI Director Francis S. Coll...g and debilitating inherited disorder. HIBM is a genetic disease with non life-threatening symptoms that emerge in adulthood and lead to slowly progressive m...

Cigarette Smoke Alters DNA in Sperm, Genetic Damage Could Pass to Offspring

...but new research shows that children could inherit genetic damage from a father who smokes . Canadian resea...e mutations persist as irreversible changes in the genetic composition of off-spring.' said Carole Yauk, Ph.D., lead author of the study and research scientist...

New Platform for Regulating Expression of Therapeutic Genes Unveiled

...ne expression patterns when delivering recombinant genetic material into cells. We had been looking for ways to regulate transgenes better, when it hit us, nature had already solved the problem for us, says Dr. Brian Brown, one of the studies authors. Now, we can utilize a cells own regulatory network to c...

Gene Responsible for Blindness in Infants and Children Identified

...ntified the CEP290 gene last year, the most common genetic cause of LCA (American Journal of Human Genetics September, 2006). By using the protein structure of CEP290, the investigators were able to discover LCA5, as they have similar structures and functions in the retina. Both the CEP290 and LCA5 genes e...

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