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Tag: "gene" at medical news

Protein Interactions Targets for Huntington Disease Therapy

...ans that if a person inherits a single copy of the gene from a parent, that person will develop the disease usually in middle age. Children born to parents who go on to develop Huntingtons disease have a 50:50 chance of having the disease themselves. Musician Woody Guthrie was among its best known suffer...

Gene Variant Responsible for Acquiring Intellect and Memory in Humans Identified

Chinese scientists have identified a unique gene variant linked with learning and memory, which may...the Kunming Institute of Zoology say that the KLK8 gene makes the neuropsin II protein, which has been found to be vital for memory and learning in mice. ...

Very Soon You can Eat to Your Hearts Content

...Baptist Medical Center have successfully deleted a gene in the mice that causes production of ACAT2, an en...y groups of female mice with and without the ACAT2 gene were fed six different diets enriched with one of these types of fat: fish oil, flax seed oil, polyu...

New Strategy Identified for Preventing Acute and Chronic Brain Disease

... in which memory deficits are triggered by a human gene that causes overproduction of A-Beta. The key find... were prevented when one or both copies of the tau gene were eliminated. Tau is made normally by brain cells and regulates the stability of their interna...

Gene Thought to Help Kill Cancer Cells may Actually Help Them Thrive

...d the Ovarian Cancer Institute has revealed that a gene , p53, thought to be essential in helping chemothe...cent of subjects whose tumors had mutations in the gene p53 were still alive after five years. Patients with normal p53 displayed only a 30 percent survival...

Study Implicates Protein as a Trigger of Advanced Prostate Cancer Recurrence

...in, named Ack1, is a member of the tyrosine kinase gene family. Ack1 exerts its effect on the reemergence of the cancer by biochemically altering the now inactive androgen receptor in the nucleus of prostate of cells, according to a series of experiments conducted by lead author Dr. Nupam P. Mahajan, assi...

It is Possible Reverse Hair Loss, US Scientists Say

...e. The Pennsylvania team found that a particular gene important in wound healing, called wnt, appeared t...mber of hair follicles. If the action of the wnt gene was blocked, no hair follicles were produced; but if it was boosted, then many more hair follicles w...

Suicide Gene Therapy Kills Bowel Cancer Cells

An innovative type of gene therapy has for the first time succeeded in making...r cells. But the researchers have added an extra gene to the virus. The virus is programmed to switch on the gene only if it reaches a tumour. When the ge...

Clock Gene Plays Role in Weight Gain, Study Finds

...edical College of Wisconsin have discovered that a gene that participates in the regulation of the bodys ...olism. Their finding shows that mice lacking the gene Nocturnin, which is regulated by the circadian clock in the organs and tissues of mammals, are resis...

Scientists Map Genome Sequence Dengue Mosquito

... aegypti. "An important part of this project is gene annotation which predicts numbers and locations of...al stages. Matching a messenger RNA to a predicted gene will validate authenticity of this gene," he explains. Zhijian Tus team has uncovered and describe...

Genetic Marker Linked to Aggressive Prostate Cancer

...er differed from that in men who did not carry the gene variant. "We found the carriers of these 8q24 markers had more aggressive tumors, said Helfand. Patients who were carriers had cancers that were more likely to spread into the lymph nodes and were more difficult to surgically remove. The patients...

Researchers Use Gene Therapy to Restore Eyesight in Blind Mice

A new study has used gene therapy to bring back eyesight in mice that had a ...of mice for two months after the administering the gene therapy injection into the subretinal space of the rodents. Scientists found that 19 out of the 21...

Chemotherapy Drug Shrinks Brain Tumors

...rticipants. In 42 percent of the participants, the gene 1p/19q was missing. Those missing the gene were more likely to respond well to the drug. They also had more months without the tumor developing...

New DNA Tests Advances Treatment of Lysosomal Storage Diseases

A new set of laboratory tests using gene sequencing is able to help confirm 24 lysosomal st...ste products that damage organs and tissues. The gene sequencing tests, developed by scientists in Emory University's Genetics Laboratory, are available t...

'Star Trek'-type Scanning may Help Reveal Genetic Activity of Tumors

..., the researchers could reconstruct 80 per cent of gene expression based on looking at standard CT scans t...ons between the imaging features and the molecular gene activity data suggests that this could be a promising and fruitful research direction," said lead au...

Exercise can Slow Down the Aging Process in Elderly People

...g in human skeletal muscle. Researchers examined gene expression profiles in tissue samples from 25 heal... younger healthy men and women age 20 to 35. The gene expression profiles or molecular "fingerprints" focused on the function of mitochondria -- the "powe...

Genes Associated With Limb Development is More Primitive Than Believed

...ms and swamps. An autopodial-like pattern of Hox gene expression in the fins of a basal actinopterygian ...apod limbs. Tetrapods have a second phase of Hox gene expression that happens later in development. During this second phase, hands and feet develop, and ...

Scientists Use Gene Therapy to Reverse Heart Failure in Animals

...researchers at Jefferson Medical College have used gene therapy to reverse heart failure in animals. In addition, they found that this gene therapy strategy had "unique and additive effects" to currently used, standard heart failure drugs ...

Aspirin may Help to Prevent Colon Cancer in High-risk Individuals

...tics and prevention found that a new Celebrex-like gene called 15-PGDH suppresses the grown of colon cancer, which may lead to the development of a new drug for colon cancer prevention. Celebrex is a naturally occurring Cox-2 inhibitor. The findings of the study were published in May issue of New Eng...

Gene Discovery Lays Groundwork for Targeted Therapies for Endometrial Cancer

Discovery of alterations in a gene called FGFR2 could accelerate the development of n...ial cancer did not have these mutations. The FGFR2 gene encodes a protein that plays a critical role in cell growth. In patients with FGFR2 mutations, the t...

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