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Tag: "estrogen" at medical news

Researchers Have Identified Subgroup Sensitive to the Drug Cisplatin

...ancers contain receptor molecules for the hormones estrogen or progesterone, and in recent years antiestrogen ...5 to 20 percent of breast tumors that have neither estrogen nor progesterone receptors and also do not overexpress HER2. Since these so-called "triple-negativ...

Expert Warn- Odds Still Stacked Against Hormone Replacement Therapy

...taking hormones, the authors suggest. In contrast, estrogen receptor-negative tumors decreased by only 1.7 percent and this change is not statistically significant. According to the authors, these findings add weight to the recommendations about limited use of HRT to treat the symptoms of menopause. Co-a...

Breastfeeding Keeps Breast Cancer At Bay- For Older Mothers

...hat breastfeeding provides protection against both estrogen and progesterone receptor positive and negative tu...ct against the type of breast cancers that express estrogen and progesterone receptors, these factors do not protect against the rarer tumors that do not have t...

Early Estrogen Therapy May Reduce Cardiovascular Risks

A new analysis of both estrogen and estrogen plus progestin shows a 24 percent reduction in risk for coronary heart disease events in women start...

More Aggressive Breast Cancer in Hispanics Independent of Health Care Utilization

...orer grade, larger tumor size and fewer cases with estrogen receptors may suggest that true biological differences exist in breast cancer by ethnicity”. Source-Eurekalert SR...

Hormone Replacement Therapy- Not A Fallen Angel

...isease, in part because their body's production of estrogen drops. Women who have gone through early menopause, either naturally or because they have had a hysterectomy, are twice as likely to develop heart disease as women of the same age who have not yet gone through menopause. Another reason for the in...

Combining Therapies can Improve Survival for Early-stage Breast Cancer Patients

...ears who have ER-positive tumors (tumors that need estrogen to grow), especially when they are not receiving chemotherapy. The researchers called for further research into this group of breast cancer patients. "Relapse-free survival benefits emerged early and were maintained, whereas overall survival bene...

Breast Cancer? ER Positive or Negative

...y rates have been most noteworthy among women with estrogen receptor (ER)-positive tumors and women younger than 70//. The results of the study are being published online April 2 in the Journal of Clinical Oncology (JCO). Approximately 75% of breast cancers are ER-positive. The average age of breast can...

Hope for Ending the Pain, Infertility of Endometriosis?

...ppress ovarian function and therefore suppress the estrogen that “seems to feed these lesions,” he says. Surgical options include a simple laparoscopy, a procedure with only small incisions that can be used to excise small lesions in cases of mild endometriosis. More severe cases may require a laparotomy, ...

Estrogen Protects Liver After Traumatic Injury

...chers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrha...ase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage,” appears in the April issue of The American Jou...

'Triple Negative' Breast Cancers Seem to Affect the Young, Minority

...osis. Three important markers in breast cancer are estrogen receptor (ER), human epidermal growth factor receptor 2 (HER2), and progesterone receptor (PR). In particular, these markers are useful in selecting appropriate adjuvant therapy and prognosis. Around 15 percent of breast cancers do not express any of...

Estradiol Guards Against Osteoporosis

...nd a novel pathway by which estradiol, the primary estrogen in humans maintains bone density. This function is...n avoiding osteoporosis. // It is well known that estrogen is essential for healthy bone, and that when the production of estrogen is reduced, as occurs normal...

Study Aims to Find Which Breast Cancer Patients Need Chemotherapy

...0 postmenopausal women with a small tumor that has estrogen receptors – most do – and no sign the disease has spread to the lymph nodes, probably 12 to 15 of the women need chemotherapy to reduce recurrence, Dr. Samuel says. To save those patients’ lives, all 100 have to be treated with chemotherapy, becaus...

Obesity And Environmental Chemicals: Research Probes Potential Link

...ne expression. Does exposure to PBDEs, which mimic estrogen and thyroid hormones in the body, make cells more likely to develop into fat cells? “Everything I do has to do with how changes in signaling result in changes in gene expression,” she says. Carey’s work is at the cellular level. Isolating the fat ...

New Study: Pine Bark Significantly Reduces Endometriosis

...24 weeks. (Leuprorelin treatment completely blocks estrogen in the body and must be discontinued after 24 week...s observed in the Pycnogenol group. Gn-RHa lowered estrogen levels drastically and in contrast, the estrogen levels of the Pycnogenol group showed no systematic...

An Aspirin a Day Keeps Heart Disease Away

...om using hormone replacement therapy and selective estrogen receptor modulators such as the osteoporosis drug raloxifene to prevent heart disease. They also say supplements such as vitamin E, C, folic acid and beta-carotene do not prevent heart disease and should not be taken to prevent it. However routi...

Tamoxifen Yields Long-term Reduction in Breast Cancer Risk

...Tamoxifen, an antiestrogen drug, is only active on estrogen receptor (ER)-positive breast cancer, which is dependent on estrogen to grow. In the International Breast Cancer Intervention Study (IBIS-I), 7,145 women ages 35 to 7...

Active Lifestyle Reduces Risk of Invasive Breast Cancer

...ng." Previous research has linked high levels of estrogen to an increased risk for developing breast cancer....udies assessing the effect of physical activity on estrogen and other hormone exposure, and other biomarkers of risk would provide valuable insights on the mech...

Plastics in Common Household Items May Cause Fertility Defects

...und that low doses of BPA in female rats inhibited estrogen induction in the brain. This can lead to learning impairment and, in old age, the onset of neurodegenerative disorders such as Alzheimer’s disease. Source-YALE University SM...

Early Switch to an Aromatase Inhibitor Increases Survival

...a period of five years. Tamoxifen was the first estrogen modulator shown to increase survival and reduce th... and anastrozole, work in a different way to lower estrogen levels. Recent evidence shows aromatase inhibitors used alone or in follow-up after two years of tam...

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