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Tag: "epithelial" at medical news

PAI-2 Plays a Pivotal Role in Eye Infections

...ogical crosstalk in human corneal and conjunctival epithelial cells,’ in Cell Death and Differentiation (http://...or suppressing gene Rb2/p130 in the nucleus of the epithelial cells in the cornea and conjunctiva. According to the researchers, this interaction with Rb2/p130 an...

Mouse Model Beneficial to Study of Head and Neck Cancer

...orming growth factor beta receptor II (TGFbRII) in epithelial cells of the oral cavity. By then introducing activating mutations in either the H-ras or K-ras (two different isoforms of the Ras GTPase), the researchers were able to induce invasive HNSCC with 100 percent incidence. ‘Head and neck lesions develo...

Receptor for H.pylori Identified in Stomach

...ecay-accelerating factor (DAF), a protein found in epithelial cells in the stomach//. Blocking this interactio...free-living, but approximately 20% bind to gastric epithelial cells. This binding induces an immune response and alters the morphology and behavior of the epithel...

Malfunction Of Key Growth Factor Increases Mortality Rate From Pulmonary Fibrosis In Blacks

...e growth factor (HGF) was reduced in the blood and epithelial lining fluid of African-American scleroderma patients than in Caucasians.And the latest study presented in San Francisco "demonstrates that antifibrotic effects of HGF are impaired in lung fibroblasts isolated from Africa-Americans may be due to the ...

New Multi-functional Sensing Tool To Investigate Cystic Fibrosis

...ensors to study ATP release at the surface of live epithelial cells (cells that cover most glands and organs in ... every 2,500 people in the United States. Using epithelial cell cultures from Emory, the Georgia Tech researchers have demonstrated that their multi-functional...

Scientists Unravel Link Between HRT And Breast Cancer Gene, BRCA1

...as in contrast to the growth stimulation of breast epithelial cells in mice (deficient in BRCA1) treated with the hormone combination. The results of the present study have several valuable clinical implications. A majority of the breast tumors have deficient expression of the BRCA1 gene. Such patients could ...

Unusual Tumor-Suppressor Gene Switches Off in Lung Cancer

... TCF21 is pretty unusual since it can alter normal epithelial cells turning them into mesenchymal cells. This particular cell has the ability to migrate to other parts of the body. Therefore, researchers suggest that silencing the TCF21 gene can help in the cancer spreading to other parts of the body. “The fact...

Tea Keeps Ovarian Cancer At Bay

...4. They found 301 who were diagnosed with invasive epithelial ovarian cancer during this time. When the study started two-thirds of the participants reported that they drank tea at least once a month. "We observed a 46 per cent lower risk of ovarian cancer in women who drank two or more cups of tea per day comp...

Cell Implants May Help Those Who Suffer From Parkinson's

... Levodopa can be produced from the retinal pigment epithelial cells of human beings which can be isolated from the eye tissue after postmortem, developed in culture, after which it can be implanted in the human brain. The cell implants have been performed upon patients who suffered from advanced stages of the P...

Another Feather In The Garlic Cap: Helpful In Avoiding Breast Cancer

... counter this activity. "We treated human breast epithelial cells with equal amounts of PhIP and DAS separately, and the two together, for periods ranging from three to 24 hours," said Thomas. "PhIP induced expression of the cancer-causing enzyme at every stage, up to 40-fold, while DAS completely inhibited t...

Gold Nanoparticles: Agents For Noninvasive Cancer Therapy

... oral squamous carcinoma cell lines and one benign epithelial cell line were incubated with anti-epithelial growth factor receptor (EGFR) antibody conjugated gold nanoparticles and then exposed to continuous visible argon ion laser at 514 nm. It was found that the malignant cells required less than half the las...

Crohns Disease Could Be Caused By Gaps In The Intestinal Barrier

... absorption of nutrients. The villi are covered in epithelial cells // which are constantly renewed – around a t...r as a result of failure in the renewal process of epithelial cells. Understanding this cell shedding process may lead to new treatments for inflammatory bowel ...

Genetic Expressions Can Influence The Process Of Aging

...lar tissues including skin and other multi-layered epithelial tissues after the animals reached maturity. The effects of premature aging observed in these p63 deficient mice (image available on request) were hair loss, reduced fitness and body weight, progressive curvature of the spine, and a shortened lifespa...

Breakthrough in cancer therapy

...t are rapidly dividing. These cells include normal epithelial cells in the hair follicle, as well as tumour cells. The Glaxo Wellcome team, led by Dr Stephen Davis, tackled the problem by stopping cell division in the hair follicles. They did this by using a compound which blocks the activity of an enzyme, ca...

Researchers Gather Stem Cells From Discarded Placenta

...acities. Researchers also said that these amniotic epithelial cells could be turned into cells that can form liv...that despite the similarities between the amniotic epithelial cells and the embryonic stem cells, these are not stem cells totally, as they will not be able to re...

Malignant Mesothelioma – A New Genetic Revelation

...d), all of whom were smokers, the remainder of the epithelial lining shows changes that may be considered as pre...d), all of whom were smokers, the remainder of the epithelial lining shows changes that may be considered as preliminary stages to the development of lung cancer,...

Malignant Mesothelioma – A New Genetic Revelatio

...d), all of whom were smokers, the remainder of the epithelial lining shows changes that may be considered as pre...d), all of whom were smokers, the remainder of the epithelial lining shows changes that may be considered as preliminary stages to the development of lung cancer,...

Women with borderline ovarian tumors can still preserve their fertility

... removed. Borderline ovarian tumors are a kind of epithelial ovarian tumors. These tumors have less chance of spreading as a malignant condition. These do respond to treatment by surgeries, but till date there had been no medical procedures that have been able to give a clear and successful treatment to the co...

Test to predict ovarian cancer

...gins in the cells of the ovaries, like the surface epithelial cells, germ cells, and the sex cord-stromal cells. This form of cancer in women is ranked 4th in terms of causing deaths due to cancer. The new test is based on four proteins, leptin, prolactin, osteopontin and insulin-like-growth-factor II, if the ...

New Hair in 15 Days Could Now Be A Possibility Say Researchers

...and resting phases. ?-catenin acts specifically on epithelial hair follicle progenitor cells, triggering a highly coordinated program of proliferation followed by expansion into the multiple differentiated cell types that comprise the mature, growing hair follicle. In contrast to the effects of transient and re...

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