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Tag: "enzyme" at medical news

Genes And Environmental Factors Determine Stress Response

...n of a gene that produces monoamine oxidase-A. The enzyme is responsible for breakdown of serotonin and other neurotransmitters. Mutation of this gene can lead to either enhanced or decreased production of the chemical. Neurotransmitters, as the name suggests are substances that communicate information to...

Facts about Common Cold and Flu

...u virus. They work by inhibiting neuraminidase, an enzyme essential for the release of recently formed virus particles from infected cells. Therefore, the drugs are able to prevent the virus from spreading inside the body. Zanamivir has just been approved by the Health Ministry to treat bird flu and the ...

LDH Measurement Can Predict Outlook Of Patients With SCD

...y a simple test // that measures the levels of the enzyme lactate dehydrogenase (LDH). Sickle cell disease i...urces of the enzyme, although trace amounts of the enzyme can be found in other cell types. Under diseased conditions, the cells that contain the enzyme relea...

Coffee Increases Heart Attack Risk In Slow Caffeine Metabolizers

...n, is however, controversial and inadequate. The enzyme cytochrome P450 1A2 (CYP1A2) is responsible for metabolism of caffeine. Genetic variation associated with this gene may either confer a quicker (CYP1A2*1A) or a slow caffeine metabolism (CYP1A2*1F). The researchers analyzed more than 2014 individuals...

Fat fighters’: Whole-grain foods’: under the microscoe

...s also been shown to interfere with the work of an enzyme called "lipoprotein lipase." VLDLs are naturally rich in triglycerides, so you want the lipoprotein lipase-your triglyceride-removing mechanism-to be very efficient. If the apoCIII protein on your VLDLs slows down the lipoprotein lipase, triglyceride...

Colour Of Urine Can Reveal The Health Status Of The Patients

... to air can also be a sign of alkaptonuria, a rare enzyme disorder that causes abnormalities of the skin and cartilages. And gout can produce pink urine. This diagnostic tool goes back many centuries. The ancient Greeks first diagnosed the rare blood disorder porphyria by observing colourful urine and eve...

A gene related to aggression weakens the brain

...ne is one of two common versions that code for the enzyme monoamine oxydase-A (MAO-A), which breaks down key mood-regulating chemical messengers, most notably serotonin. Structural MRI in 97 subjects was taken for the study and the results were that those with L showed reductions in gray matter (neurons a...

Azathioprine to Treat Eczema?

.... They did this by matching doses to levels of an enzyme in the blood that can break down the drug, so pati...y. Each was given a test to determine levels of an enzyme called TPMT in their blood. The dose of Azathioprine they subsequently received was individually t...

Bad Enzymes Found To Enable Brain Recovery Following Stroke

...d new generation drugs in treating the same. The enzyme matrix metalloproteinase-9 (MMP-9) has been found to help in remodeling of the brain 14 days following stroke, in experiments conducted on animal mouse models by Harvard medical school researchers. The results of the study can be found in April issue...

First Gene Therapy Human Trial For Muscular Dystrophy In Progress

...ther genetic disorder called Canavan's disease, an enzyme deficiency disorder," Samulski said. "We were the first academic institution to ever make FDA-certified AAV vectors to go into the brains of children with Canavan's disease. So we had cut our teeth and had a bit of a track record by 2002, and that's ...

Pain-killer Drug Can Help Fight Breast Cancer

...g medication helps by halting the production of an enzyme that is key to a common form of breast cancer. The...imesulide stopped the production of aromatase, the enzyme implicated in estrogen-dependent breast cancer. This form of cancer is the most common breast cancer...

Gender Question Solved

...to the production of eggs. In the case of males an enzyme is present in male embryos that wipes out retinoic acid and so suppresses meiosis before birth, resulting in sperm production. Further research is to be carried to figure out what triggers and suppresses meiosis. This would later help the researc...

UC Researchers Find Potential Drug Target For SARS

... other institutions have found the structure of an enzyme in the virus that causes SARS//, severe acute resp... unlocking the three-dimensional structure of this enzyme -- known as papain-like-protease (PLpro) -- we now have a molecular road map to design new drugs tha...

Rice University wins Prestigious Grants from HHMI

...ified yeast, which in turn will produce sufficient enzyme for systematic study. This will be followed by structural studies of the products of these target enzymes with the help of gas- chromatography or other equally cutting-edge techniques. Followed by their lab work, the students will be granted an oppor...

Ontario’s Entire Drug System Undergoes a Revam

...drugs that treat rare diseases such as Fabry's, an enzyme disorder. Even in the case of Herceptin the anti breast cancer drug the province has been much slower than other jurisdictions to cover the drugs. New Democrat health critic Shelley Martel also said that reforms will be introduced in which the patien...

Estrogen also a potential neurotransmitter

...e-tuned by a rapid decrease in the activity of the enzyme that synthesizes the estrogen, thus leading to changes in the amount of estrogen available for action.” He added, “In the past, scientists have always assumed that the action of estrogens on brain function required at least a few hours or days to pr...

Mouse Models To Determine The Cause Of Aggressive Leukemia

... from the other chromosome. Bcr-Abl encodes for an enzyme called a tyrosine Kinase. This causes the abnormal...ivation of Arf in ALL cells expressing the Bcr-Abl enzyme gives these cells a strong proliferative nature which might contribute to imatinib resistance. So th...

46-Year-Old Canada Man Donates A Part Of His Liver To A Complete Stranger

...up a notch,' he said. The child had an intrinsic enzyme deficiency that placed him with the constant risk of permanent brain damage, coma and eventually death. 'Imagine if your child had to take a special formula and medications every six hours -- in fact about 40 pills a day and had to be on a severely r...

Sepsis risk increased due to the absence of one key enzyme

The presence of caspase-12, touted as the wonder enzyme in sepsis increases the bodys vulnerability to bac...ncy confers strong resistance to sepsis. // This enzyme appears to modulate inflammation and innate immunity in humans. "The results of the study make cle...

Polymer Molecule Layered On Carb Molecule to Increase Sensitivity

...sitivity of the detector, but after that, the more enzyme layers" inhibit diffusion of the glucose. Now that the glucose enzyme biosensor has passed the test, Lin said, it should be possible to build a similar sensor using other...

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