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Tag: "enzyme" at medical news

Sitagliptin, Under Investigation For Type 2 Diabetes

... called DPP-IV inhibitors, which inhibit the DPP-4 enzyme that normally inactivates the incretin gut hormones GLP-1 and GIP.The patients studied exhibited a safety and tolerability profile similar to placebo. In addition, patients taking Sitagliptin experienced no significant weight gain and a low risk of h...

Green Beans for Cancer Prevention and Treatment.

... it is found that beans and wheat bran contains an enzyme inhibitor Inositol // pentakisphosphate which is f...have anti-cancer effects by blocking the action of enzyme Phosphoinositide 3 kinase. Dr. Marco Falasca and colleagues from the University College London has ...

Smoking Hazardous To The Enzymes System In Lungs

... may be understood by the effect it has upon a key enzyme in the // lungs. Monoamine oxidase A (MAOA) is important in mood regulation and breaking down compounds that help to regulate blood pressure. In a new study, researchers at the National Institute of Drug Abuse and colleagues elsewhere carried out a ...

Old is gold– proved yet another tim

...he break down of red blood cells in people with an enzyme deficiency. People would have to be tested for the same before the therapy can be instituted....

Women might be at increased risk of HIV during pregnancy

...dex women. HIV status was assessed by two separate enzyme immunosorbent assays with western blot confirmation of discordant enzyme immunosorbent assay results and HIV seroconverters. The authors interpreting the results suggest t...

High-Fat Diet Can Ward Off Inflammation In The Gut

...imulate the intestine to trigger the release of an enzyme called a hormone called cholecystokinin, or CCK. This enzyme is responsible for digestion of the food and also satiation, a feeling of fullness that is a silent ...

US Kidney Failure Rates show Stabilization After 20-Year Climb

...ven to the use in 1990s of angiotensin-converting enzyme inhibitors (ACE-inhibitors) and angiotensin receptor blockers (ARBs), which lower protein in the urine and are thought to directly prevent injury to the kidneys' blood vessels; and also to better control of diabetes and blood pressure. NKDEP encou...

Digestive acid production dependent on newly found hormone

...reted intestinal protein limits the activity of an enzyme called cholesterol 7a-hydroxylase (CYP7A1) critical to bile acid production. Animal models lacking FGF15 were found to have increased CYP7A1 activity and excrete greater quantities of bile acid. The results of the present study have valuable clinic...

Sugar Helps Control Cell Division

..., cells that had higher than normal amounts of the enzyme that removes the sugar from proteins ended up with nuclei that didn't look right under a powerful microscope. Instead of being disseminated fairly uniformly through the entire nucleus, the genetic material of these cells was bunched up, giving the co...

Urine testing for telomerase enzyme for bladder cancer diagnosis

...e 90% accurate is used to measure the level of the enzyme telomerase in urine of patients. The results of th...r cancer and tested for the presence of telomerase enzyme in their urine, which is present in most of the cancers. The enzyme check was compared to urine cyto...

Bortezomib for salvage therapy against progressive myeloma

...bits the proteasome, a // multicatalytic cellular enzyme whose activity entails several molecular mechanisms, including, in particular, the NF-kB pathway. Currently, bortezomib, alone or in combination with dexamethasone and doxorubicin, is under investigation as first-line and maintenance therapy. Howev...

Persons With Fatty Liver More Prone For Hypertension

... later lead to hepatitis or cirrhosis. The liver enzyme GGT, commonly measured to test liver function is strongly affected by variation in weight and, most importantly, body fat distribution. Infact GGT was a significant predictor of hypertension only among overweight participants with increased central b...

New anti-aging molecule could be coming up in way

...The protein has been found to act by activating an enzyme called manganese superoxide dismutase (found in the mitochondria of the cell), which hydrolyses the harmful superoxide to less harmful hydrogen peroxide. Free radicals are chemical entities that contain free electrons and because they contain free ...

Enzyme Linked To Spread Of Skin Cancer

A new study says that a key enzyme present in skin cancer cells might be responsible ... of the cancer to other parts of the body. // The enzyme named focal adhesion kinase (FAK) is actually a critical component of the healthy cell and plays a v...

Another Feather In The Garlic Cap: Helpful In Avoiding Breast Cancer

...as. "PhIP induced expression of the cancer-causing enzyme at every stage, up to 40-fold, while DAS completely inhibited the PhIP enzyme from becoming carcinogenic." The finding demonstrates for the first time that DAS triggers a gene ...

Aspirin reduces skin cancer Risk

...f Dermatology. Aspirin is a cyto-oxygenase (COX) enzyme inhibitor, which suppresses the activity of this enzyme and its expression. The COX gene is gene coded which is important for the growth of blood vessels. A...

Rodents to be replaced with Dogs for cancer Research

...dogs as the researchers feel that drug metabolize, enzyme kinetics and drug action mechanisms in dogs are si...s and help make those trials more efficient”. The enzyme systems and kinetics pathway in humans are similar in dogs which make the researchers measure the en...

Chronic Myelogenous Leukemia (CML) Has An Answer Now!

...new, fused gene (called BCR-ABL), that produces an enzyme called Bcr-Abl, which permanently "turns on" cell growth signals that are normally controlled by another group of enzymes phosphatases. Because of Bcr-Abl, production of white blood cells gets out of control, leading to CML. At the early stage (chro...

Disparity In Survival Rates In US and Canadian heart Patients

...ly (28.7 % vs. 25.4 %), but angiotensin-converting enzyme inhibitors less frequently (54.3 % vs. 63.4 %). The US patients had lower risk characteristics on admission and lower crude mortality rates at 30 days and 1 year. The death rate at 30 days was 8.9 % for U.S. patients, which was significantly lower a...

Identification Of Gene Sequence To Promote Growth Of New Arteries

...he DNA sequence of the MMP2 gene, which encodes an enzyme believed to promote the growth of new arteries. This can be found in the November 8 issue of the Proceedings of the National Academy of Sciences. Understanding the development of new arteries is very essential because when there is an insufficient b...

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