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Tag: "enzyme" at medical news

Cure For Pompe Disease

Pompe disease is a rare inherited enzyme deficiency that destroys muscles and can kill infants at a very young age. Myozyme is a drug developed by Genzyme// to treat this disease. Genzyme, a biotechnology company in Cambridge, Mass said that it has spent more than $500 million since 1998 to...

Milking the ship of the desert for 'white gold'

...who suffer from "lactose intolerance" and lack the enzyme necessary to break down the sugar in cow's milk. It is non-allergenic because it lacks the two types of protein responsible for allergies brought on by cow's milk. It also has a low fat content of about two percent and of a type that is mostly poly...

Milking the ship of the desert for 'white gold'

...who suffer from 'lactose intolerance' and lack the enzyme necessary to break down the sugar in cow's milk. It is non-allergenic because it lacks the two types of protein responsible for allergies brought on by cow's milk. It also has a low fat content of about two percent and of a type that is mostly poly...

Indicator of your state of mind is your saliva

...aliva can determine the level of alpha amylase, an enzyme secreted by the salivary glands that has been linked in previous studies in adults to the sympathetic nervous system’s ‘fight or flight’ response to stress. Douglas A Granger of Pennsylvania State University, the lead author of the four team studi...

UK Computer Grid In Bird Flu Fight

...al compounds that can inhibit the activities of an enzyme on the surface of the influenza virus, the so-call...ugs today on the market is viral neuraminidase, an enzyme that helps the virus to proliferate and infect more cells. As this protein is known to evolve into v...

Revelation Of Cancer Agent Could Help In Developing Effective Cancer Drugs

...e effective cancer drugs. The over-activity of an enzyme called telomerase is believed to contribute to the...called telomeres. In most healthy adult cells, the enzyme is completely shut down. However, cancer cells find a way to activate telomerase - triggering unc...

Alzheimer's-linked apolipoprotein E produced by neurons, Gladstone study

...hat apoE in neurons is subject to processing by an enzyme that clips off a portion of the protein, resulting in toxic fragments that escape the secretory pathway and enter the cytosol (the fluid portion of a cell's cytoplasm). Studies now underway at Gladstone and elsewhere indicate that those fragments may...

HCV Spree in US

...vide their blood samples for HCV testing and liver enzyme analysis. Dr. Gregory L. Armstrong, from the Centers for Disease Control and Prevention in Atlanta, and colleagues report that the highest rate of infection is found among people aged 40 and above....

PI-103 Effective against Brain Cancer

...rtant new targets, especially PI3 alpha kinase, an enzyme often found to be overactive in brain, breast, colon and stomach cancers. But the sheer number of related kinases – 15 in the PI3 kinase family alone – and uncertainty about how each acts in the body – has stalled progress. Broad spectrum drugs that ...

Rare Genetic Disorder Could Cause Strokes In Young People

...hough the condition's progress can be slowed using enzyme replacement// treatment, says a study. The disor...sufficiency. It is caused by a missing or faulty enzyme needed by the body to process oils, waxes and fatty acids, reports the online edition of BBC News. ...

Birth Defects Link With ACE Inhibitor Use, FDA Reports

...ts born to mothers who took angiotensin converting enzyme inhibitors (ACE inhibitors) during the first trimester of pregnancy had an increased risk of major birth defects, compared with infants whose mothers did not take these medications. Out of 29,507 infants whose TennCare records were examined for th...

New Revolutionary Drug Could Stop the Spread of HIV

...cations work by blocking reverse transcriptase, an enzyme that enables HIV to replicate within a cell. Others disable protease, which helps to assemble the virus into particles to infect other cells. The new drug, a derivative of betulinic acid, is a cheap by-product of the paper industry and one of a new...

Transport of Proteins Unravels the Mystery behind Neurodegenerative Diseases

...inhibition of fast axon transport by activating an enzyme called JNK that can inhibit these transport protei...e cell body. The link to the activation of the JNK enzyme suggests a new therapeutic target that might limit, delay or perhaps prevent progressive neurodegene...

Transporter offers reliable clues for safer pain medicine

...f a novel concept. Conventional wisdom was that an enzyme was responsible for hydrolyzing, or decomposing, opioid peptide, Dr. Ganapathy says. This is the case for at least one neurotransmitter – acetylcholine, implicated in Alzheimer’s - which is inactivated by an enzyme, rather than being transported back...

Genetic Link to Adrenal Tumor Revealed

...revealed that a genetic deficiency of an important enzyme can result in a rare tumor of the adrenal glands appears //. The enzyme is one of a class of enzymes involved in halting a cell's response to hormones and appears to stop c...

Coffee Drinking Associated with Lower Risk for Alcohol-Related Liver Disease

...sis. Among those who had their blood drawn, liver enzyme levels were higher among individuals who drank more alcohol, indicating liver disease or damage; however, those who drank both alcohol and coffee had lower levels than those who drank alcohol but did not drink coffee, with the strongest link among th...

Clues To Identify Psychological Seizures

...tion of IV drugs and had lower blood levels of the enzyme creatine kinase, which normally rise after epileptic seizures. “These characteristics can help guide the emergency doctor to the correct diagnosis, which is so critical in these cases, because the drugs can result in severe complications if it is ...

Site of Sleep Regulation Identified in Fruit Flies

... regulation, Sehgal manipulated the activity of an enzyme known as protein kinase A (PKA). Previous work in Sehgal's lab revealed that the higher the level of PKA activity, the lower the period of immobility, or sleep, in the fruit fly. By building upon this work, Sehgal and others set out to increase PKA a...

Animal Study Found Cure For Huntington Disease

...firmed that the deadly cleavage is caused by a key enzyme called caspase-6. By blocking the action of this target, they showed that the mouse did not develop any symptoms of Huntington disease. Hayden's team is now trying to test this model of prevention in a mouse using drug inhibitors and then ultimately ...

Host of Benefits from Erectile Dysfunction Drugs

...in common and work by limiting the activity of the enzyme phosphodiesterase-5, which is found in tissues and vessels of the penis, blood platelets, and smooth muscle of blood vessels. For the treatment of erectile dysfunction, the drugs’ constraint of the enzyme’s action results in increased levels of cycli...

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