Rapid Aging of Arteries In People With Advanced Heart Disease
...ry cells age. They found that the artery cells divide seven to 13 times more rapidly than normal in a patient with heart disease leading to premature aging of the arteries. With aging, the arteries lose their ability to prevent fatty acid deposition leading to narrowing of arteries and heart attack. T...Study Findings Could Help In Developing A Better Drug Delivery System
...lic acid. Cancer cells need folic acid to grow and divide and, therefore, have developed abundant receptors to capture it. These receptors are largely absent in normal cells. This means folic acid, and the drug linked to it, is attracted to the pathologic cells and is harmless to healthy cells, Low said. ...Gene May Regulate Cellular Aging
...cate that certain stem cells lose their ability to divide and replace themselves with age as the expression of p16INK4a increases,' said Sharpless, a member of the UNC Lineberger Comprehensive Cancer Center. The trio of reports are published online Sept. 6 in the journal Nature. The three research teams ar...Key Gene Controlling Eye Lens Development Identified
...e part of the brain called the cerebrum to fail to divide normally into two lobes. Holoprosencephaly is the most common abnormality of the development of the forebrain (front part of the brain) in humans. A few years ago the St. Jude team demonstrated that Six3 activity is critical for the normal developmen...Yale Scientist Received Medical Science Prize From Keio University
... development of resistance and that since bacteria divide so rapidly, people must be responsible when using antibiotics because “evolution will trump intelligent design.” Steitz has been a member of the Yale faculty since 1970, arriving directly after completing his post-doctoral training at Harvard and a...Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum
..., where cells that should not be dividing start to divide because of a defect in a signaling pathway starting at the cilium” This sensory role of primary non-motile cilia has now become the model for many other diseases and syndromes, all of which trace back in many different tissues to defects in receptor...There appears to be something of a great divide in terms of flesh, between the less informed chips and pizza chomping Britons and their health conscious watch –what –you -eat// fellow citizens. The National Health Service (NHS) is seriously worried about rocketing obesity figures that cost the N...Characteristics of Fast-Growing Skin Cancers
...th fewer moles and freckles, and its cells tend to divide more quickly and have fewer pigments than those of slower-growing cancers. “Anecdotal experience suggests that there is a form of rapidly growing melanoma, but little is known about its frequency, rate of growth, or associations,” the authors write ...Stem Cell Activity Deciphered in the Aging Brain
...brains are not reduced in number, but instead they divide less frequently, resulting in dramatic reductions in the addition of new neurons in the hippocampus. To conduct their census, the researchers attached easy-to-spot fluorescent tags to the neuronal stem cells in the hippocampus in young, middle-aged...Selective Marker Found to Indicate Aggressive Form of Breast Cancer
...ructure of adult stem cells as they regenerate and divide into daughter cells. 'Normal basal epithelial tissue produces nestin, but basal epithelial tumors produce a tremendous amount of nestin, which likely represents an abnormal expansion of the basal epithelia.' DiRenzo said. 'If it is indeed specific...Selective Marker Found to Indicate Aggressive Form of Breast Cancer
...ructure of adult stem cells as they regenerate and divide into daughter cells. 'Normal basal epithelial tissue produces nestin, but basal epithelial tumors produce a tremendous amount of nestin, which likely represents an abnormal expansion of the basal epithelia.' DiRenzo said. 'If it is indeed specific...Reactivated Genes Cause Tumors to Shrink (or) Disappear
...more likely to become cancerous, because they will divide uncontrollably even when DNA is damaged. In this study, the researchers used engineered mice that had the gene for p53 turned off. But, they also included a genetic "switch" that allowed the researchers to turn p53 back on after tumors developed. ...Researchers On The Path To Building Bone
...ensity can increase either because more bone cells divide or fewer cells die due to apoptosis. Pten is a tumor suppressor gene that applies a break on the main cell survival pathway, causing cells to die,” said Thomas L. Clemens, Ph.D., professor of pathology and director of the UAB Division of Molecular an...Cancer Research May Help Biofuels
...es a plant's genetic code so the cells continue to divide past their ordinary stopping point. In the end, the genetic manipulation leads to increased seed size and seed count. In experiments, the technique has increased overall crop yield by as much as 20 percent. It also works in a similar fashion in di...Abnormalities in Eye Movements and Attention can Predict Schizophrenia
...ties in eye movements and attention can be used to divide people into two groups in relation to schizophrenia-related risk. “Schizophrenia affects one in every 100 people,” said Lenzenweger, who considers it the costliest form of mental illness known to humankind. It has a strong genetic component; about ...Stem Cells in Liposuctioned Fat can Heal Injuries
...d off, and stem cells rely on them heavily as they divide and mature. The Oslo team has found that low rates of DNA methylation, for instance, boost the chances of transforming fat stem cells from one cell type into another. "Look at a cell’s epigenetic profile," says Collas, "and you may be able to predict...Triptolide: A Potential Drug for Polycystic Kidney Disease
...t, cells destined to line a kidney tubule grow and divide until the tubule is formed, as sensed by fluid flow in the tubule. Fluid flow bends the primary cilium, giving a signal to stop cell growth. PKD is caused by a mutation in the PKD1 or PKD2 gene causing the cells to miss the “stop growing” signal, all...Health Workers in Developing Countries Undermines Essential Services
... health outcomes are growing wider, and these gaps divide rather precisely along the lines of poverty and wealth," she said, adding, "Health needs in populations left behind by socioeconomic progress are also left behind by the R&D agenda." For example, only a single class of widely effective malaria drugs ...New Test Helps Identify Hepatitis C Patients at High Risk of Developing Cirrhosis
...-stage liver disease, the researchers were able to divide them into a high-risk category based on their gene pattern, compared with those who had low-risk gene patterns. "The Cirrhosis Risk Score was superior to the known clinical factors, such as alcohol consumption, in predicting the risk of developing ci......all of which are special because they can grow and divide into multiple types of cells. Stem cells that are derived from embryos are the most potent of all stem cells because they are able to mature into any cell type in the body. There are stem cells in a few places in the adult body, too, but these are mo...