New Prostate Cancer Vaccine Shows Promise
...dritic cells contain genetic information or RNA, a derivative of DNA, from a substance secreted by the prostate gland called prostate specific antigen. PSA, prostate-specific antigen levels increase in prostate cancer patients. These dendritic cells are then injected under the patient's skin to trigger immune s...Sun Pharma to launch chiral version of omeprazole soon
...in this month. The chiral version of molecule is a derivative with lesser side-effects// and, hence, could be termed as more efficient than the molecule itself. Officials of Sun Pharmaceuticals confirmed about the introduction of the product shortly in the Indian market. However, any further details as to the ......ell.// Researchers found that stents coated with a derivative of the cancer drug paclitaxel - which inhibits cell division - failed to keep blood vessels open in the majority of a small group of patients, resulting in heart attacks in 3 cases. In angioplasty, a balloon-tipped catheter is threaded into a blocke...Vitamin D May Aid Breast Cancer Treatment
...in mice, adds to a growing body of evidence that a derivative of vitamin D known as EB1089 may yield some powerf...r cells. An analog is a synthetic, laboratory-made derivative of a parent compound -- in this case vitamin D -- that is genetically engineered by adding or removi...Vitamin D Wipes out Cancer Cells
...e to mice exposed to both radiation and EB 1089, a derivative of vitamin D. After treatment, the tumor volume in those women treated //with EB 1089 was 50-percent lower than in the group that received radiation alone. Radiotherapy is commonly used to treat breast cancer, both before surgery to reduce tumor siz...New medicine for ovarian cancer
... a process called angiogenesis. The new drug is a derivative of an immuno-suppressant drug called rapamycin. Cancer in humans includes a high level of activity of an enzyme called AKT. This enzyme controls the cell activities, cell divisions and how the cell will respond to chemotherapy. AKT pathway remains h...Gene treatment maintains normal Heart Beat
...nsplants. These cells were injected with a genetic derivative of phospholamban called antisense phospholamban. The antisense gene transfer is designed to specifically block formation of phospholamban genes. According to him, by delivering this specific genetic information to the cells we improved calcium movem...Broccoli Found to Block Cancer Progression In Both Animal and Human Studies
...h and regulation. Laboratory tests showed that the derivative of isothiocyanate significantly pushed the human lung cells to commit 'suicide', compared to cells that did not have the gene, suggesting that its use may stop fast growing lung cancer cells from the outset. However researchers say that it is diffic...Artemisinin May Prevent Breast Cancer
A derivative called artemisinin which comes from the sweet wormwood plant may help to prevent breast cancer from setting in, according to researchers of the University of Washington.// Artemisinin has been used to combat malaria since early times. Henry Lai, w...Treatment Resistant Tumors Can Be Targeted Better Using Botox
...apy, employed in cancer treatment. // Botox is a derivative of Botulinum toxin, a naturally occurring chemical known to cause intestinal poisoning. The toxin has numerous clinical applications such as relieving facial spasms, strabismus and treating muscle hyperactivity. The toxin acts by blocking release o...New Compound Offers Hope In Liver Cancer Treatment
...inked to inflammation. The synthetic compound, a derivative of oleanolic acid, belongs to a class of compounds commonly referred to as triterpenoids. Previous studies have established the anti-tumor properties of oleanolic derivatives in animals and humans. In order to assess the effectiveness of cancer pre...JRRD Focuses On Issues Such As Spinal Cord Injury and Prosthetics
...reased slightly while taking Hectorol, a synthetic derivative of vitamin D. Vitamin D has been shown to increase BMD and reduce fractures in osteoporosis. An analysis of how effective is the treatment in patients needing arm-hand reconstruction following SCI showed that surgery combined with functional elect......er birth and the result is sperm. Retinoic acid, a derivative of Vitamin A, causes germ cells in female embryos to begin meiosis, leading to the production of eggs. In the case of males an enzyme is present in male embryos that wipes out retinoic acid and so suppresses meiosis before birth, resulting in sperm p...Researchers Develop Potent Cancer Killer From Vitamin E Derivative
...modeling, the researchers found that the vitamin E derivative works because it lodges in a groove in the structure of the Bcl-xL protein, disabling it. However, the vitamin E molecule has a long, coiled, protruding tail that keeps the molecule from fitting tightly, and more effectively, into the groove. ‘On...Bladder Pain Suppressed By Marijuana-Derived Drug
IP 751, a derivative of Marijuana has been found to suppress bladder pain associated with interstitial cystitis (IC) in animal models//. The synthetic drug is a analog of a metabolite of THC, the principal component of marijuana. The results of the new study presented at...Smoking Increases Osteoporosis Risk
... to correlate serum levels of cotinine, a nicotine derivative that only appears in blood of those exposed to tobacco smoke, with serum hormone levels. (Source: Eurkalert)...New Revolutionary Drug Could Stop the Spread of HIV
...particles to infect other cells. The new drug, a derivative of betulinic acid, is a cheap by-product of the paper industry and one of a new class of drugs called maturation inhibitors. It works by interfering with the production of the capsid protein, a conical "shield" which protects the genetic material ...New Group Of Drugs For HIV Treatment
...ein,this group of drug in question, PA- 457, is a derivative of betulinic acid, and interferes with the production of the capsid conical shield which surrounds the genetic material of the HIV inside it. Approximately 80 per cent of people on treatment for HIV show resistance to one or more of the prevalent...Genetic Map Reveals How Drugs Fight Diseases: Study
...rom the connectivity map involves gedunin, a plant derivative that, despite a long history of medicinal use, is not well understood molecularly. Another key finding suggests a new way to overcome drug resistance in cancer, according to the researchers. Using the connectivity map, another team led by Scott A...Genetic 'Roadmap' Charts Links Between Drugs and Human Disease
...rom the Connectivity Map involves gedunin, a plant derivative that, despite a long history of medicinal use, is not well understood molecularly. The researchers identified gedunin in a high-throughput chemical screen for molecules that disrupt hormone signals in prostate cancer cells and then used the Connectiv...