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Tag: "cultured" at medical news

Role of MicroRNA in Cancer Suppression Identified

...y, activation of p53 in-vivo in mice as well as in cultured human cells induced the expression of a specific microRNA (miR-34a). Based on the likelihood that miR-34a could itself play a role in cellular apoptosis, researchers introduced miR-34a directly into human cancer cell lines to determine its impact on ...

Scientists Develop Artificial Blood Vessels for Vascular Grafts in Mice

...rotational vacuum seeding device. After they had cultured their vascular constructs for seven days, the researchers implanted them in the abdominal aortas of rats eight weeks before performing tests to determine how well the grafts had performed. It was found that the cell-seeded constructs showed a signi...

Researchers Link Bacteria Destroying Proteins to Alzheimer's Treatment

...wed in significance and overall importance. Using cultured cells from mice, the scientists showed that the an...sing imaging and biochemical techniques to see, in cultured cells, how the antibodies affect the clusters. "We have many indications that antibodies work. Now ...

Girls With Cancer Given Fertility Hope

...aining egg producing follicles. The eggs were then cultured to make them viable. In the case of the five-year-old, who is still receiving therapy for kidney cancer, seven eggs were obtained, one of which was successfully matured. Ariel Revel from Hadassah University Hospital in Jerusalem will present full...

DNA-damage Test Could Aid Drug Development

...arrow cells derived from these mice, and the cells cultured from that bone marrow, proved more sensitive to the toxic agents than were the cultured cells from normal mice, further confirming the results. With the new assay, 'instead of testing on...

Nanomedicine Gives the Way for Nerve Cell Regeneration

...ned nanofiber scaffolds. When the nerve tissue was cultured on unaligned nanofibers there was no nerve fiber growth onto the scaffolds. However, on aligned nanofiber scaffolds, they not only observed nerve fibers growing from the tissue but the nerve fibers were aligned in the same orientation as the nanofibe...

Significant Scientific Breakthrough in Stem Cell Banking

...uture use. After thawing, MSCs can be successfully cultured using new techniques developed by Cryo-Save, which will greatly increase the potential number of stem cells available for future therapies....

Nutrient-rich Dairy Beverages an Emerging Market

...king place. For instance, branded yoghurt/curd and cultured milk/lassi are growing at a rate of 14 percent and 33 percent respectively. Leading players in the Indian dairy industry like Amul, Nestle, Mother Dairy and Britannia are already in the probiotic milk and milk product market. An internationally reput...

Menthol Receptor-A Thermosensitivity Determinant in Cold Temperature

...logy at Yale, and colleagues, found that isolated, cultured nerve cells that express TRPM8 react to cooling stimuli, but cells cultured from mice lacking TRPM8 do not. Also, mice engineered without TRPM8 are much less sensitive to cold ...

Single Cancer Stem Cell may Be Sufficient to Initiate and Maintain a Malignant Tumour

...ated that an injection of a single cell taken from cultured LA7 cells into mouse breast tissue can seed a new mammary carcinoma . The results of the efforts of an international team of researchers led by Dr. Dulbecco, President Emeritus and Distinguished Resident Professor at the Salk Institute for Biologic...

Cells Responsible for Spread of Breast Cancer Identified

...ry gland, we developed a model of the breast using cultured cells grown outside the body. Through this model we first investigated how normal breast development occurs. We then went on to discover how to make these cells behave like migrating cancer cells, which move through the body unlike normal cells, in o...

Cytokine Resistance Contributes to Pathology of Type 2 Diabetes

... the researchers demonstrated that human monocytes cultured under type 2 diabetic conditions had impaired interleukin-4 signalling, an important player in the immune response in that it steers macrophages toward the production of other anti-inflammatory cytokines. Boffins say when IL-4 binds to its receptor...

Green Tea Compound may Be a Therapy for Rheumatoid Arthritis

...surrounding the capsule of the joints -- then were cultured in a growth medium and incubated with the green tea compound. The fibroblasts were then stimulated with pro-inflammatory cytokine IL-1?ò, a protein of the immune system known to play an important role in causing joint destruction in people with rh...

A Newly Identified Immunosuppressive Protein in Rheumatoid Arthritis

... novel study of DcR3, the researchers isolated and cultured FLS from 19 patients with RA, obtained during total knee replacement surgery. For comparison, FLS was also extracted in a similar manner from 14 patients with osteoarthritis (OA). For all samples, expression of DcR3 in FLS was measured by reverse-tra...

Estrogen Protects Liver After Traumatic Injury

...e was diminished by blocking protein production in cultured liver cells. Blockade of estrogen receptor-alpha had no effect on cells, but GPR30 silencing resulted in decreased Bcl-2 and active protein kinase A. By identifying GPR30 and the downstream pathways (Bcl-2 and active protein kinase A) involved in e...

Scientists Re-grow Dental Enamel from Cultured Cells

...nth-old pigs continue to proliferate when they are cultured on top of a special feeder layer of cells (the fee...y being reported today, the researchers seeded the cultured dental epithelial cells onto collagen sponge scaffolds, along with cells from the middle of the toot...

Nanoparticle Research Offers Hope of Artificial Retinas, Prostheses

... a cell-friendly coating of amino acid, and placed cultured neurons on the very top. When light shines on them, the mercury-tellurium nanoparticle film layers produce electrons, which then move up into the PDDA film layers and produce an upward-moving electrical current. "As you build up the layers of this,...

Green Tea and COX-2 Inhibitors Combine to Slow Growth of Prostate Cancer

...ues looked at the effects of the two substances on cultured human prostate cancer cells. Alone, both EGCG and NS-398, a COX-2 inhibitor similar to celecoxib, demonstrated the ability to slow cancer cell growth and limit the presence of known cancer-promoting proteins within the cell samples. Together, EGCG an...

Treatment Extends Survival in Mouse Model of Spinal Muscular Atrophy

...tors can increase the amount of SMN2 expression in cultured cells and that treating pregnant mice with an HDAC...eased the amount of SMN2 gene activity in both the cultured cells and the mouse model. Next, the researchers gave daily injections of TSA to the SMA mice, st...

Master Switches Found for Adult Blood Stem Cells

...3 microRNAs into adult stem cells. They'll then be cultured in Petri dishes. MicroRNA-155 - the first microRNA tested - was predicted to stop stem cells from developing into red and white blood cells. As expected, stem cells without microRNA-155 matured: they formed approximately 75 red and 150 white blood ...

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