UK Scientists to Reveal Genetic Secrets Behind Serious Illnesses
...d risk of being obese compared to a person with no copies of that version, scientists found. Those carrying two copies of the variant had a 70% increased risk of being obese, and were on average three kilos heavier tha...World’s First Attempt To Restore Sight Using Gene Therap
...w experimental procedure involved inserting normal copies of the faulty RPE65 gene into cells of the retina -the light-sensitive layer of cells at the back of the eye - using as a vehicle like a harmless virus or vector. The doctors operated first on Robert Johnson, a UK man born with a sight disorder w...Gene Mutations Leave Caucasians Prone To Heart Diseases And Diabetes
...nt of the people they tested had mutations in both copies of this DNA stretch, giving them a 64 percent high... risk of a heart attack than people who carried no copies of the mutation.McPherson's team said 20 to 25 percent of Caucasians they tested carrying two mutate...The DNA That Spells Double Risk of Heart Attack
...and other from the father, And those who carry two copies of this heart attack causing strand, suffer an enhanced risk of having a heart attack. Such people are prone to suffering a heart attack even when they are young and 64% are likely to suffer a heart attack during any stage in life. Those portrayi...New Clues for Treatment of Disease That Causes Accelerated Aging
...nusual mutations caused them to make many more bad copies of the gene's primary protein, lamin A, than proge...amin A may take place even in people with "normal" copies of the gene. Scientists suspect that accumulation of these bad copies may contribute to aging. If so...Sony Apologises to Church of England Over Computer Game
...eet Sony executives next week, have called for all copies of the game to be pulled from the shelves and for Sony to make a "substantial donation" to religious charities....Life Functions Governed by Circadian Rhythms-new Research
...Ptitsyn also discovered alternative short and long copies of some genes oscillating in the opposite phase. These genes are essential components of leptin signaling system, responsible for the sensation of satiety after eating. The oscillating pattern varies in different organs and determines the effect of l...Alli- a New Weapon for War Against the Bulges
...to accompany the starter pack, a Web site, 200,000 copies of a diet plan and 800,000 copies of a book to help dieters combine the pill with weight-loss programs. People who take Alli while imp...New Gene Discovery Raises Hope for Childhood Blindness Cure
...essive gene, a child would need to be carrying two copies of the gene to develop LCA, one from each parent. However, the disorder is more widespread within populations where marriage to first or second cousins is common, such as the Pakistani community. "If a parent is found to carry a mutation in the LCA...Researchers Find New Target to Treat Type 2 Diabetes
... be phosphorylated cause the liver to produce many copies of the fat metabolism genes. We hope that drug companies will look for new ways to modify fat metabolism in type 2 diabetics using these possible targets, Birnbaum said. The findings of the study were published in Nature....A Novel Target for Type-2 Diabetes Atk2
...C-1a that could not be phosphorylated put out many copies of the genes for fat metabolism. Each approach pointed to the same conclusion: PGC-1a had phosphate groups added to it by Akt2/PKB in the presence of insulin and this prevented the turning on of genes that make fat. There are currently no drugs tha...UK Scientists Identify Gene Mutations That Trigger Breast Cancer
... one in 16 women are estimated to carry two faulty copies of one of these genes. The three other genes identified in the study are also common among the population but carry a lower risk of disease, said Cancer Research UK, which helped to fund the study. Professor Bruce Ponder, one of the leaders of the ...New Mouse Model to Aid in Cancer-causing Genes Hunt
... which lead to defects like missing genes or extra copies of genes some of which are key to the tumors formation. As part of the study, researchers used gene knockouts to develop mice whose cells dont have molecules which guard the genome from instability in the DNA. Researchers created mice which forme...Denial of Treatment for HIV Infected Child Sparks Outrage
...Minister Surya Kanta Mishra for help and also sent copies to the president and the state Governor Gopalkrishna Gandhi for their intervention. "We draw your urgent attention to the most reckless incidence of medical failure as three major government hospitals in Kolkata (SSKM, MCH and NRS) have refused.....Scientists Map Genome Sequence Dengue Mosquito
...ome. "Although the majority of protein coding TE copies in Ae. aegypti appear to be degenerate, a significant number of elements have potentially active TE copies, indicating that they may be developed as tools for genetic studies of mosquitoes," said the researcher. "If you look at the genome as an ec...New Strategy Identified for Preventing Acute and Chronic Brain Disease
...cits in these mice were prevented when one or both copies of the tau gene were eliminated. Tau is made normally by brain cells and regulates the stability of their internal skeleton. In AD, tau is altered in a way that makes it aggregate into clumps, called tangles. A lot of effort has been devoted to fi...Cataloging the Structural Variations in Human Genetics
...In some cases, individual genes appear in multiple copies because of duplications of DNA segments. In other ...tions of particular genes or parts of genes. Extra copies of a gene known as CC3L1 reduce a person's susceptibility to HIV infection and progression to AIDS. ...Hepatitis C Carries Another Risk-Cancer Of The Immune System
...lls flock to the infection site, then make lots of copies of themselves to outnumber the viruses or bacteria that they want to kill. Most of the copies are normal, but a few have genetic mistakes, or mutations, that lead to cancer. Worldwide, about o...Genetic Variation is Linked to Substantial Risk in Heart Attack
...rcent of individuals of European descent carry two copies of the genetic variation (one from each parent), found on chromosome 9p21. The research project was led by the Icelandic genomics company deCODE Genetics, along with U.S. researchers at Emory University School of Medicine, Duke University, and the...New Clues for Treatment of Disease That Causes Accelerated Aging
...nusual mutations caused them to make many more bad copies of the gene's primary protein, lamin A, than proge...amin A may take place even in people with "normal" copies of the gene. Scientists suspect that accumulation of these bad copies may contribute to aging. If so...