Cancer drugs in development nearly doubled since 1995
...rms various CancerInstitutes are investigating 402 compounds for the treatment of variouscancers, up from 215 in 1995. Many of the drugs are alternatives to standardradiation and chemotherapy. For lung cancer, the leading cause ofcancer-related death in the United States, there are 68 drugs in the pipelinesof ...... sunscreen, code-named 855, is structurally unlike compounds in current use. It has an It has demonstrated great efficiency in absorbing and dissipating UV radiation in the damaging UV-B region of the spectrum.All the completed tests indicate that the new sunscreen is not irritating to use as it has low allerg...New FDA Approved Drug To Treat Migraine
...percentage of side effects. However this class of compounds has the potential to cause coronary vasospasm, and as a result Axert is not advised for patients with ischemic or vasospastic artery disease. This drug is introduced by the pharmaceutical company, Pharmacia. Results of controlled clinical trials dem...New treatment for Osteoporosis
...es rather than hours.The team developed a calss of compounds that produce only the fast signals. Rats, given the new compound show up to 70% increase in bone strength. According to Kousteni it could even strengthen the bones in healthy people.......periods and restoring fertility.The plant contains compounds similar in structure to sex hormones. One of these reduces// prolactin levels in the body slightly, which both alleviates the symptoms of PMS and may also help increase fertility. The plant also contains a substance which controls lutenising hormone....... vitamin did not change the level of isoprostanes, compounds that may play a role in cell and tissue damage cau..., discovered isoprostanes in 1990. Since then, the compounds have become the best measure of oxidant stress,a damaging process accelerated by smoking and other c......es. Rutin is a flavonol, part of a larger group of compounds called flavenoids, and is believed to be a powerful antioxidant.// The researchers noticed that flavonol production depended on the enzyme chalcone isomerase (CHI). By inserting a Petunia gene that encodes for CHI, they engineered tomatoes with ski......er damage.// The Researchers discovered three new compounds that might explain why the avocado is protective. ...rs in this case are looking to identify the active compounds in the fruit so that they can be produced as a drug or a supplement. However, this is not the best w...Antioxidants found in chocolates
...ved substances contain some antioxidants, often as compounds known as flavonoids. It has been found in a study that chocolate contains higher levels of health-promoting flavonoids than apples or orange juice. Antioxidants block the action of harmful free radicals, which are produced when oxygen burns glucose i...Osteoporosis Drugs: right time to take-off
...n both the physician as well as patient level. New compounds that rebuild bone mass and are associated with minimal side effects represent another area of opportunity. Currently, Selective Oestrogen Receptors Modulators (SERMs) such as Raloxifene and new generation bisphosphonates such as Risedronate have not ......ioxidants such as vitamin C can "neutralize" these compounds and reduce damage, free radicals can also deplete antioxidants from the body when overall levels are low. The investigators found that patients with PAD had vitamin C blood levels nearly twice as low as those in people without PAD....Hydroxyurea derivatives kill colon cancer cells
...ory and in mice, according to researchers. The new compounds seem to be very interesting for the treatment of these tumors. // Previous drugs derived from hydroxyurea were extremely active in blocking the same cell targets as hydroxyurea, but had serious side effects. This prompted the researchers to synthes...Garlic fights malaria and cancer
A group of compounds commonly found in garlic may not only an effective...f Tropical Medicine and Hygiene in Atlanta.// The compounds called disulfides, occur naturally in garlic, onions and mahogany trees and are known to have antifu...Lecithin lowers cholesterol absorption in body
...lesterol is not going into the blood stream.” The compounds are naturally occurring or derived from their natu...rs which could lead directly to development of new compounds for lowering cholesterol. Koo anticipates that regulatory barriers to such development will be low.K......ext stage for the researchers is to identify which compounds in the onions has the positive effect, and to see if it will work in humans."We hope we have opened up a new field and that this will be a possibility to prevent osteoporosis provided it works in humans and that humans can eat sufficient amounts of t...New Dietary Approach To Manage Kidney Stones
...e, a compound that combines with calcium and other compounds to form the deposits commonly known as kidney stones, the researchers explain. Low-calcium diets, on the other hand, may reduce urinary excretion of calcium but they also cause levels of oxalate in urine to rise....Link between chlorine byproducts and pregnancy risks
...s runoff from farms or lawns, however, it can form compounds such as chloroform that can cause illness. The study released by the Environmental Working Group and Public Interest Research Groups identified areas that may have increased health risks including miscarriage, neural tube defects and reduced fetal ...Focused Treatment For Childhood Cancer
...athway active," says Pomeroy. Recently developed compounds that can block the uncontrolled SHH signaling found in the tumors could potentially be used as a therapy in children with medulloblastoma. Researchers also found that the clinical outcome of an individual child's struggle with medulloblastoma could b...Caution On Use of Cholesterol Drugs
...watch what may happen" as they take the drugs. The compounds may cause abnormal liver function, and at least one version of the pills, which was recalled, was linked to kidney failure. The new guidelines combine the growing realization that elevated cholesterol early in life can cause deadly cardiovascular c......e synonymous with good health. They are a class of compounds thought to prevent certain types of chemical damage caused by an excess of free radicals, charged molecules that are generated by avariety of sources including pesticides, smoking and exhaust fumes. Destroying free radicals may help fight cancer, hea...