Brain Swelling Key to Reducing Stroke Fatalities
...els and water accumulation in the skin tissue. A compound known as substance P has been shown to contribute to this swelling in the skin, Ms Turner says. Blocking substance P reduces skin tissue oedema. “Until recently, neurogenic inflammation was not known to occur in the brain following injury. Our labo...New Company Will Seek Drugs Against Diabetes and Cancer
...ne. Do the flies get better? If you find the magic compound that hits everything that contributes to the disease in just the right amount so that the fly can live, then you've made true progress." Medros gives the researchers a mechanism to obtain private drug libraries, establish the effectiveness of their...Monoclonal Antibody based system for Anthrax detection
...t to a special "carrier" protein and injected this compound into mice. Usually, carbohydrate antigens bring about weak immunological reaction whereas, this carrier protein stimulated a stable one. Monclonal antibodies were produces and isolated from these immunized mice. These antibodies bound exclusively ...Cancer-Killing Compound From A Fungus
A cancer-killing compound called rasfonin has been synthesized from a fungus..."In 2000, scientists in Japan discovered that this compound might have some tremendous potential as a prototype anticancer agent, but no one has been able to st...A Synthetic Molecule Instigates Cancer Cells To Self-Harm
...rother, "As such, the potential effectiveness of a compound such as PAC-1 could be assessed ... with a high degree of accuracy, and people with cancer could be pre-selected for treatment with a procaspase-3 activator based on the concentration of procaspase-3 in their tumor cells."...Drugs Activating PXR May Help In Treating Niemann-Pick type C disease
...dilantin, the antibiotic rifampicin and the herbal compound St. John's Wort. Additional experiments are under...e using the mouse model of NPC to test a synthetic compound that activated genes for proteins that break down cholesterol and remove it from cells. At the same ...Improper Usage Of Sunscreen Can Harm Skin
...diation can harm the skin.One example of a harmful compound is ROS, which causes skin damage and hastens aging process. 'Sunscreens do an excellent job protecting against sunburn when used correctly. This means using a sunscreen with a high sun protection factor and applying it uniformly on the skin,' said H...Stress Could Have A Notable Effect In Quickening The Progression Of Alzheimer's disease
...rld. Earlier this year, he announced work on a new compound that not only relieves the cognitive symptoms of Alzheimer’s disease, but also reduces the plaques and tangles in the brain. Source-urekalert VIK...Solution to Bacterial Mystery Promises New Drugs
...-positive pathogens first use PlsX to synthesize a compound called fatty acyl-phosphate, then use PlsY to transfer the fatty acid to G3P. These steps initiate membrane phospholipid formation required for cell growth. “Our discovery of PlsX and PlsY not only solved a troublesome mystery,” Rock said. “It’s al...Study States That CNS Could Regulate Arthritis
...livery system to administer miniscule amounts of a compound that blocks these signals only in the CNS and then determined the influence of the treatment on peripheral arthritis. We observed that the p38 signal is turned on, or activated, in the central nervous system during peripheral inflammation," Fireste...Nitric Oxide Levels In Brain Indicate Sleep
... that when cats are awake for prolonged periods, a compound called adenosine accumulates in their brains, ulti...lts were identical when the researchers injected a compound that scavenges nitric oxide – mops it up and renders it inactive. In contrast, when the basal fore...Study Findings Could Help In Developing A Better Drug Delivery System
... sites, called receptors, on the cell surface. The compound is then broken down and processed, releasing the drug. One of the key mechanisms of this breakdown is disulfide reduction, which involves the breaking of chemical bonds. It was thought that disulfide reduction relied on the movement of the material......thoxycinnamate. After just 1 hour, they found each compound had sunk into the skin, meaning its protective effect was greatly reduced. Worse, Hanson's team found that the samples contained more reactive oxygen species (ROS) than skin exposed to UV with no sunscreen on it. ROS are free radicals that can damage...Immune Response Linked to “Ghost” Parasites and Severely Congested Sinuss
...archers say that although chitin, a rigid chemical compound common to fungi, insects and roundworms, is not naturally found in the human body, the presence of its corresponding enzyme and its role in the buildup of mucus and fluids, and polyp formation makes the enzyme a legitimate target for drug therapies t...Cranberry Juice Could Fight E. coli Bacteria
...e found that Tannins (called proanthocyanidins), a compound found in cranberry juice can render E. coli bacteria ineffective. The bacteria are also known to cause urinary tract infections apart from other diseases. Urinary tract infections (UTIs), each year affect eight million people, mostly women, the eld......rieties of brown seaweed show the presence of this compound in high concentrations. However, green and red sea...er 200 rats and mice. The study revealed that this compound acted in two ways to fight flab. A protein called UCP1that causes breakdown of fat, seemed to be a...Anti-Cancer Compound In Broccoli
...and scientists have said that they have isolated a compound from vegetables, which has anti-cancer properties. Researchers at Christchurch School of Medicine said that// they have isolated some compounds from the cruciferous family of vegetables, which can kill cancer cells resistant to other treatments. Br...Insight Into Tanning Process Suggests Novel Way to Prevent Skin Cancer
...ediatrics at Children's Hospital Boston. While the compound used in the study has not yet been tested in human...d the skin of red-haired, fair-skinned mice with a compound known to increase cAMP levels. The compound, called forskolin, is derived from the root of the forsk...Bacterial Protein Shows Promise in Treating Intestinal Parasites
...toxin and sent it to Cappello, who then tested the compound in a laboratory model of hookworm infection. “It worked on the first day,” said Aroian. “Laboratory animals treated with Cry5B survived a lethal hookworm infection, and showed no side effects from the medication.” Colleagues in Cappello’s lab th......ws a "pro-drug" compound. Inactive by itself, this compound can be taken for as long as necessary without side effects. It is activated only when it comes into contact with a specific enzyme attached to the stent by its manufacturer. In effect, the enzyme on the stent then becomes a "pharmaceutical factory" t...