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Tag: "chemotherapeutic" at medical news

Scientists Destroy Cancer Cells Using Electric Pulses

...f the cells without the use of potentially harmful chemotherapeutic drugs," he added. The researchers successfully ablated tissue using the IRE pulses in the livers of male Sprague-Dawley rats. "We did not use any drugs, the cells were destroyed, and the vessel architecture was preserved," Davalos said. Dava...

Bak Protein Sets Stressed Cells on Suicide Path

... they blocked oxygen supplies and used the common chemotherapeutic agent cisplatin, then documented that filamentous mitochondria became fragmented very early and quickly in apoptosis. Ironically they also found the deadly fragmentation results from Bak's interaction with mitochondria-shaping proteins called ...

New Genetic Studies Carried Out in Cancer Therapy

...idual genes that are associated with resistance to chemotherapeutic drugs and sets the stage for future studies that m...using a functional genomic screen. Resistance to chemotherapeutic drugs is the primary cause of treatment failure in patients with metastatic cancer. Dr. Julian Downw...

Tree Bark Substance may Hold New Lung-cancer Treatment

...ancer Center. This is the first step in developing chemotherapeutic agents that exploit the proteins needed for a number of cellular processes, such as DNA repair and programmed cell death. About 85 percent of patients with non-small cell lung cancer have cancer cells containing elevated levels of the NQO1 enzyme, ...

DNA-damage Test Could Aid Drug Development

...ay to examine how different individuals respond to chemotherapeutic agents. 'The presumption is that, for some biological processes, in vitro human models could be closer to in vivo human than in vivo mouse,' notes Shuga. 'That premise will be tested in coming years as new systems become available.'...

Most Pediatric Chemotherapy Mistakes Reach Patients

...e study concluded that the antimetabolite class of chemotherapeutic agents are most likely associated with errors, and...nts under 18 years old and 310 of these involved a chemotherapeutic drug. The authors of the study found that 85 percent of these errors reached the patients. Sixteen...

Estradiol Guards Against Osteoporosis

... and pathogenically after exposure to radiation or chemotherapeutic drugs, bones become brittle and break easily. Howe... for 24 hours to a drug called etoposide, a cancer chemotherapeutic drug that promotes apoptosis. Results showed that caspace-3 activity decreased in cells treated wi...

Oral Hygiene Can Prevent Tooth Decay for Patients With Cleft Conditions

...od feeding habits and general oral health. 3. Use chemotherapeutic products to clean intraoral appliances when removed from mouth. 4. Avoid kissing the baby’s lips and sharing food and utensils. 5. Brush teeth at least once a day. 6. Have regular dental examinations every 6 months. Fluoride supplements in nonfluo...

Mining of Ancient Herbal Text Leads to Potential New Anti-Bacterial Drug

...w bark, and the molecular basis of the anti-cancer chemotherapeutic agent Taxol? was derived from the bark of the Pacific yew tree. So it’s not so far-fetched to think that the contributions of an ancient text and insights from traditional medicine really may impact modern public health,” explains Brent Bauer, M.D., ...

Ancient Herbal Text Paves the Way to Novel Anti-bacterial Drug

...w bark, and the molecular basis of the anti-cancer chemotherapeutic agent TaxolTM was derived from the bark of the Pacific yew tree. So it's not so far-fetched to think that the contributions of an ancient text and insights from traditional medicine really may impact modern public health," explains Brent Bauer, M.D.,...

Mining of Ancient Herbal Text Leads to Potential New Anti-Bacterial Drug

...w bark, and the molecular basis of the anti-cancer chemotherapeutic agent Taxol? was derived from the bark of the Pacific yew tree. So it’s not so far-fetched to think that the contributions of an ancient text and insights from traditional medicine really may impact modern public health,” explains Brent Bauer, M.D., ...

Researchers Find Stem-cell Therapy Effective in Targeting Metastatic Cancer

...fied neural stem cells to activate and concentrate chemotherapeutic drugs predominately at tumor sites, so that normal...ltrate metastatic tumor sites, and then activate a chemotherapeutic drug, thereby localizing the drug's effects to the tumor cells. The technique takes advantage of t...

Genes That Allow Brain Cancer-Causing Stem Cells to Resist Treatment Identified

...ells have a significant resistance to conventional chemotherapeutic agents. We also link this resistance to genes that are known to inhibit a cell death process called apoptosis,” said neurosurgeon John S. Yu, M.D., co-director of the Comprehensive Brain Tumor Program at Cedars-Sinai and senior author of the journal ...

A Collaboration to Find New Tools to Fight Leukemia

...ledge and their understanding of the highly potent chemotherapeutic antibiotic pentostatin to try to develop an even better treatment option. The investigators initiated a trial of three weeks (one cycle) of combined chemotherapy drugs pentostatin (P), cyclophosphamide (C) and rituximab (R) repeated in six cycles for...

A Promising New Vaccination Strategy for Late-Stage Melanoma

...hat the success criteria that have been applied to chemotherapeutic investigational new drugs, for instance, are not necessarily those by which immunotherapies should be judged,” Dr. Old says. “Yes, the ultimate endpoint would be complete, long-lasting remission, as sometimes happens in these vaccine studies,” Dr. ...

Study Findings Could Help In Developing A Better Drug Delivery System

...istol-Myers Squibb's proprietary epothilone cancer chemotherapeutic agents. Source-Eurekalert VI...

Cancer Drug Helps An Anti-Cancer Virus To Act More Exhaustively

... out a solution for this problem they found that a chemotherapeutic drug called cyclophosphamide has the ability to briefly weaken these immune cells, thereby giving the anti-cancer virus an opening to spread entirely through the tumour enabling it to kill more cancer cells. Specifically, the drug slows the activit...

New Company Will Seek Drugs Against Diabetes and Cancer

...oaches that go after one disease target, such as a chemotherapeutic drug that aims to influence one gene responsible for cancerous growth. "With our method, we aren't asking what the target is — we're letting the system tell us," Cagan says. "We're just asking for the bottom line. Do the flies get better? If you fi...

Medication Errors Affect Leukemia Treatment In Children

...rrors. The study says that more than 10 percent of chemotherapeutic medications were given incorrectly to outpatients.... errors were identified in 17 of 172 (9.9 percent) chemotherapeutic medications and impacted 13 of 69 (19 percent) pediatric patients. Of the 17 errors, 12 were attribu...

Stem cells help in the understanding of drug-resistant, recurrent tumors

... samples and to study their responsiveness to both chemotherapeutic agents and to novel agents specifically targeted to stem cell as individualized therapy of the future." Donahoe is the Marshall K. Bartlett Professor of Surgery at Harvard Medical School. Source :Eureka Alert ...

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