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Tag: "caspase" at medical news

EpiCept Accelerates Development of Phase I Clinical Study for Cancer

...itors discovered by EpiCept. These compounds cause caspase activation, cell cycle arrest, and apoptotic death in cancer cells. The Phase I trial of EPC2407 is now being conducted in three U.S. cancer centers and will administer increasing doses to small groups in approximately 30-40 patients with advanced ...

Cells Re-Energize to Come Back From the Brink of Death

...he St. Jude team discovered that a cell that lacks caspase activation and cannot undergo apoptosis increases the levels of an enzyme called GAPDH in order to counteract the backup program called caspase-independent cell death (CICD). GAPDH appears to prevent CICD by supporting the functioning of the mitochon...

Breakthrough In The Identity Of Compounds That Encourage Stem Cell Growth

...rowth factor receptor, and decreased those such as caspase 8 which play a role in apoptosis. LXA4 had the opposite effects. Source-Eurekalert VIK...

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