Profiling of Cancer Genes May Lead to Earlier Detection Human Cancers
... analyzed 45 of these new genes in both normal and cancerous tissues from the same patients and found that many of the genes were methylated specifically in the tumor samples. “We ended up with a large number of genes that are involved in the development of lung cancer that, despite years of work in the fie...Researchers Identify New Drug Targets for Cancer
...g chromosomes – was first proposed as the cause of cancerous tumors nearly a century ago by German biologist Th...th, or was a consequences of the accrued damage in cancerous cells,” said Cleveland.To find out, researchers in the Cleveland lab created and analyzed mouse mode......t other tumor cells. Though successive trials on cancerous tumors of mice have been carried out, use of virotherapy as the third arm of cancer treatment, along with radiation and chemotherapy is still several years of research away, says Seymour. The scientists plan to begin trials of the coated virus on h...'Beavertail' Surgery Helps Tongue Cancer Patients
...h swallowing. The surgery involves removing the cancerous tissue and replacing it with a healthy paddle of skin and connective tissue with artery intact, and connecting it to healthy blood vessels in the neck. The beavertail of fat that comes with the skin is connected to the base of the tongue to add bulk,...Surgery and Adjuvant Therapy Can Work for Pancreatic Cancer
...ve margins (some healthy tissue cut out around the cancerous cells), between 1975 and 2005, to remove pancreatic adenocarcinoma. They excluded patients who had metastatic cancer, tumors that could not be removed or were not removed entirely (positive surgical margins), or indolent (slow growing) tumor types. ...Role of RNA in Checking the Development of Tumors
...R gene could help prevent the growth of neoplastic cancerous cells, ordinary cells which develop into tumour cells, such as in prostate cancer cells," explains Dr Akoulitchev. "In fact, the first anti-cancer drug, Methotrexate, acts by binding and inhibiting the enzyme produced by this gene." Dr Akoulitchev b...‘Sweet Revenge’ on Inflammatory Bowel Diseae
...ctivate cytotoxic T-cells, allowing us to kill the cancerous cells as well.” Source-Medinda ANN...New Test Predicts CLL’s Sensitivity to Experimental Drug
...year, is an easy mark for the new drug because the cancerous cells are strongly dependent on a particular survival molecule, Bcl-2, that keeps the self-destruct signals at bay. They showed that the investigational drug neutralizes the Bcl-2 action, unleashing molecules that trigger suicide in the cancer cells,...Cancer Scientists' Gene Research Offers New Treatment Hope
...nes in causing the uncontrolled proliferation of a cancerous cell into a tumour. The radical approach is to use molecules of RNA - a substance similar to a gene's DNA - to "silence" or switch off certain key genes known to be involved in the growth of tumours. One team at the University of Oxford has shown i...Scientists Identify Pancreatic Cancer Stem Cells
... in pancreatic cancer, the research team implanted cancerous tissue from human pancreatic specimens removed during patient surgery in “xenograft” mice with compromised immune systems. Researchers removed tumors after they grew, and then sorted millions of cancer cells to isolate those that had one or more of t...Funds and Hope for Breast Cancer Patients
...d the magic bullet because it directly attacks the cancerous cells without side effects like hair loss or vomiting, costs about Rs.100,000 (over $2,000) per shot. For a full treatment, six to seven doses might be required which brings the costs to Rs.600,000-700,000. Not everyone can afford this kind of treatm...New Protein Inhibitor Halts Growth Of Cancerous Cells
... BI 2536 can indeed effectively halt the growth of cancerous cells, both in cell culture and in an animal model for human tumor growth. BI 2536 caused growth arrest and cell death in cell lines derived from a variety of human cancers, and it inhibited the growth of human tumor grafts in mice, resulting in the ...Liver an Excellent Target For Cancer Gene Therapy
...ental new understanding of the differences between cancerous and normal liver cells. The findings signal a new ...od vessels. The research also demonstrates that in cancerous cells the receptor for adenovirus, called the coxsackie-adenoviral receptor or CAR, is expressed ran...Cancer Drug can Extend Survival in Patients With Deadly Brain Tumors
...vastin, a relatively new type of drug that shrinks cancerous tumors by cutting off their blood supply, can slow...dard chemotherapy agent in patients with recurrent cancerous brain tumors called gliomas. They found that the two drugs together halted tumor growth up to twice ...Colorectal Cancer Getting Missed Out in Office Setting
...of colorectal polyps which are likely to turn into cancerous cells by inserting an illuminated tube with a camera in the bowl. This detection procedure is generally recommended to people when they are around 50 years unless there is a family history of the same wherein it is done earlier than this. If everyt...The Link Between Rheumatoid Arthritis and Cancer
...al nervous systems; cancers of the blood cells and cancerous tumors; but excluding non-melanotic skin cancers. Then, they compared these rates with the rates of cancer in the general population from the same geographic area, Norfolk, adjusting for difference in age and sex. Overall, the incidence of cancer was...New Protocol Targets Aggressive Brain Cancer
...individual beams of radiation to target only those cancerous areas, effectively carving out the tumor from the surrounding normal brain tissue. This allows doctors to deliver higher doses of radiation to kill the cancer because normal tissue will not also be damaged. Results to date are preliminary but encou...Ovarian Cancer May Mimic Fallopian Tube Formation
...ch and the Ovarian Cancer Institute (OCI). Using cancerous and non-cancerous tissue straight from the operating room, Bowen and fellow OCI researchers are engaged in investigating the molecular profile of ovarian cancer tissue in order to discover the causes of ovarian cancer, develop a reliable diagnostic b...Major Gene Study Uncovers Secrets of Leukemia
...t why progenitor cells get stuck in the primitive, cancerous stage, the more likely we’ll be able to design new therapies that eliminate them. That could help us continue our successful efforts to increase the survival rate of ALL.” One potential strategy for eliminating leukemic cells would take advantage o...... cancer. The researchers analysed 210 samples of cancerous tissue, surveying a family of 500 genes, called ki...hat appear to be involved in driving the growth of cancerous tumors was larger than expected, but ultimately the technique will allow scientists to acquire a com...