Tag: "blockade" at medical news
Myostatin gene could hold the key to treatment for DMD
...ies of mice and is also planning to test myostatin blockade
in dogs with DMD, since dogs are larger and have a more severe disease than the mice. He added that testing the strategy in animal models of limb-girdle muscular dystrophy is also in the pipeline. Kathryn Wagner, on the other hand plans to take thes...
Mode Of Action Of The Anti-Convulsant Valproate
...activity. Valproate also showed a dose-dependent blockade
of DHT's suppression of AR-mediated NF-êB activation in human mammalian cells. By contrast, CBZ had no significant PR, AR or ER agonist or AR and ER antagonist bioactivity but at the highest concentration tested it did antagonize PR activity. The...
Multiple Sclerosis Can Be Treated By Blocking Fat Hormone
... and colleagues investigated the effects of leptin blockade
on the induction and progression of EAE in mice. They found that leptin blockade
in mice, by the use of either anti-leptin antibodies or a form of the leptin receptor unable to bind...
Alcoholism Drug Vivitrol Approved By FDA
...to opioid receptors in the brain, resulting in the blockade
of the neurotransmitters that are associated with alcohol dependence. This blockade
may help patients reduce alcohol consumption although the exact mechanism responsible for the reduct...
PI-103 Effective against Brain Cancer
...ignals that trigger the spread of cancer. The dual blockade
proved to be a safe and effective inhibitor of cancer cell proliferation in mice with the human tumors, the scientists found. The glioma research is being published online May 15 by the journal Cancer Cell. A description of the strategy used to id...
Lebanon Fears of Epidemics as the Crisis Deepens
... increasing, we are soon moving towards a de-facto blockade
of the country," said a spokesperson for the UN High Commissioner for Refugees office. Israel's bombing of all the roads north of Beirut used by UN agencies as major supply routes arriving via Syria mean that "we will be faced with empty warehouses...
Limb Transplantation with a Difference
...set of experiments, mice not given a costimulation blockade
rejected their new limbs after about 10 days, wher...average of 222 days. "Research into costimulation blockade
is relatively new," Tung says. "And just over the last few years, a half dozen new costimulatory pat...
FDA Approves First-of-its-Kind Drug to Treat Rare Blood Disorder
...ignificantly fewer blood transfusions. Soliris' blockade
of the body's natural immune system increases the patient's susceptibility to certain serious infections, particularly meningococcal infections that can cause bacterial meningitis, an infection of the tissue surrounding the spinal cord and brain. Ser...
Mayo Clinic Physicians Have Adapted Real-time 3-D Ultrasound Imaging Devices
... the benefits of real-time 3-D ultrasound in nerve blockade
in more than 150 surgeries of varied types. Their presentations at scientific meetings and publications in peer-reviewed journals have informed other physicians worldwide into how this next-era ultrasound imaging technology may assist in peripheral...
Protein Interaction is a Drug Target for Blood Clot Prevention
...lecules to platelet integrin alpha-IIb beta 3, and blockade
of this binding is effective in the prevention of ...od from the heart to the lungs. Furthermore, this blockade
results in very little pathological bleeding, which can often occur when the clotting process is dis...