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Tag: "block" at medical news

A new century of Alzheimer's disease research

... loss of tau, or tau accumulates into tangles that block these roads,” he says. “We don’t have evidence as to whether it is the tangles or the loss of tau that is causing cell death. “The tangles we see are an end-stage event, whereas there is plenty of tau aggregation that occurs before these roadblocks...

Structure of TB Enzyme Points the Way to New Drugs: Study

...aid they had also identified a compound that could block the suspect protein, but they were concerned that by inhibiting this one protein, they would interfere with the action of other similar proteins secreted by the host cell. "We wanted to be sure that inhibitors of mycobacterial PknG would not intere...

Draft National Policy on Sight-saving Drugs unacceptable

... growth factor (VEGF). All three drugs potentially block the effects of VEGF. Wet age-related macular degeneration is the third most common cause of blindness worldwide. It affects around 2.3% of over-65s in Europe. In the UK around 26,000 people develop it each year and 245,000 are blind or visually imp...

Strange Sex Life of Mole-rats may Provide Clues About Human Infertility

...fects their fertility. There appears to be a total block to puberty in almost all the non-breeding mole-rat...l she is ready to mate.However, the stress-related block to fertility was reversible, said Dr Faulkes. When the queen died, other non-breeding but high-rank ...

Sea Snail Venom Paves Way for Potent New Painkiller

...o morphine therapy. The treatment is expected to block the calcium channels of the nerves that transmit pain signals in the body. It targets a particular subgroup known as N-type calcium channels , which play a role in some kinds of pain. Prialt is 1,000 times more potent than morphine but, unlike that...

Translating Structure into Function

... A molecule that fits the enzymes active site will block its activity just what many promising drugs do. ...molecules to fit in the active site and physically block enzyme action. But the research team sought to divine from an enzymes structure just what natural mo...

Skin Rashes Signifies Longer Survival in Cancer Patients

...nib, cetuximab, panitumumab and others designed to block overproduction of the epidermal growth factor receptor - but it is the most detailed analysis to date. The study, published in the July 1 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, reports that for...

American Bests Japanese Hot Dog Eating Champion, Sets Record

...Chestnut when a sudden urge to vomit forced him to block his mouth with his hands and settle for second place -- disqualification follows if vomit spills out of the mouth. Chestnut, a 23-year-old student from California, won the mustard-yellow championship belt and a prize of 10,000 dollars, but above all ...

New Strategy to Counter Problem Drinking

.... The drug is an opioid antagonist that works to block the effects of endorphins. The U.S. Food and Drug Administration has not approved nalmefene for use in alcohol treatment; the drug is primarily available in investigational studies. Karhuvaara said his study also suggests that practically any docto...

Fibrinogen may Inhibit Spinal Cord Regeneration

...y after spinal cord injury by discovering a way to block activation of neuronal receptors by fibrinogen. Identifying the specific inhibitors that impede the repair process could provide ways to regenerate and connect the damaged nerves and initiate recovery from paralysis after spinal cord injury. Inhib...

European Commission Seeks To Dispel The Darkness Out Of Sunscreens

... suntan. The Commission plans to ban the words sun block and 100 per cent sun protection from bottles of s... no such thing, while brands that use the term sun block will have to find another description. Says Meglena Kuneva, the Consumer Affairs Commissioner: Consu...

Eyeglass Guide Launched That Aids in Choosing the Right Eyewear

...nsitions(R) lenses -- that automatically darken to block 100% of the sun's eye-damaging rays. In addition, the guide provides several tips on selecting frame shape, color and material best suited for the individual. "Transitions' eyeglassguide not only educates consumers about the different lens and fram...

Scientists Find New Way to Kill Antibiotic-resistant Bacteria

... bisphosphonates, widely prescribed for bone loss, block this enzyme and prevent bacteria from spreading an...cteria. It was found that bisphosphonates could block the spot where the enzyme handled DNA. The researchers say that the drugs steal the DNA binding site...

Hormone Inhibitor in Prostate Cancer Treatment

... male hormones. However, this treatment does not block the production of male hormones elsewhere in the body. Abiraterone, a drug that is taken orally, inhibits an enzyme called CYP450c17, which is critical to the production of the male hormones not only in the testes, but also at other sources. Dr. Al...

Eco-architecture Takes Root in Thailand, but Growth is Slow

...rm behind Ocean 1 Tower, an eco-friendly apartment block the firms says will be the tallest building in Thailand. He estimates that making Ocean 1 energy efficient costs just one percent of the total outlay, and says the money is quickly made back in energy savings. The 91-floor luxury block, due to be...

Scientists Revealed the Key Molecule That Controls Pain

... and should make it possible to develop drugs that block the receptors actions, said Dr Thompson. Inhibiting P2X as a potential pain-relief therapy would be the Holy Grail of rational drug design and could revolutionise the way we manage chronic pain conditions like back pain and migraine....

Protein Interaction is a Drug Target for Blood Clot Prevention

...arterial disease, altered platelet aggregation can block blood vessels and cause heart attack or stroke. ...d clots. However, chronic use of oral drugs that block alpha-IIb beta 3 activation have not proved beneficial in preventing recurrent blood clots. In a s...

Tumor Blood Flow can Improve Chemotherapy

...lastoma treatment by using the drug bevacizumab to block VEGF, a protein that stimulates blood vessel growth in tumors and then following with the chemotherapy drug topotecan, which depends on blood vessels to penetrate the tumor and kill the cancer cells. A report on this work appears in the current issue...

Canadian Cancer Society Calls for Ban on Asbestos

...commend that the federal government stop trying to block efforts by the Rotterdam Convention, an UN-organized body, at its meeting in 2008, to place the variety of asbestos mined in Canada on the list of the world's most dangerous substances....

Bak Protein Sets Stressed Cells on Suicide Path

...the cell suicide mechanism is developing drugs to block it in the case of a stroke, for example, or induce it to kill cancer. Dr. Dong recently received a 1.1 million dollars, four-year renewal grant from the National Institute of Diabetes & Digestive & Kidney Diseases to further study the structural ...

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