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Tag: "biochemical" at medical news

'Gender-Benders': Sports and Sex Determination

...atest cyto-molecular techniques, complemented with biochemical and endocrinal evaluations will definitely be a 'curtain-raiser', and will go a long way in helping to detect the 'wolves' among the herd of 'sheep'. RJA...

Bernard Rimland, the Pioneer of Modern Autism Research Dies.

... Rimland concluded that autism was the result of a biochemical defect. He also suggests that mercury in vaccines could be a cause. Autism is characterized by poor language skills , poor communication and social skills.It is reported that his son , Mark had autism. Rimland was born in Cleveland in 1928. When ...

Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum

...ansport (IFT). These initial observations led to biochemical and genetic studies showing that molecular motors controlled movement of the IFT particles. When the motors were stopped, flagella would not form, and already-formed flagella became shorter. They also showed that the IFT particles served as transport...

Parkinson's Mutation Stunts Neurons

... the LRRK2 protein is an enzyme called a kinase--a biochemical switch that activates other proteins by attaching a molecule called a phosphate to them. In their experiments, when the researchers generated mutant forms of the enzyme, they discovered that the mutants showed higher-than-normal enzymatic kinase ac...

New Technique to Detect Cancer in Early Stages

...n the cells, Huang said. Varying combinations of biochemical molecules create a "fingerprint", helping in determining whether the cell is normal or not, he said. Conventional methods of optical testing used normal white light or ultraviolet light. White light allows doctors to view only late-stage tumours ...

Insect Protein Effective for Treating Heart Enlargement, Arrythmias

... The work is important because it identifies a new biochemical target for the development of drugs to treat enlargement of the heart and arrhythmias – conditions that have few treatment options and ultimately progress to heart failure and sudden cardiac death. ”Enlargement of the heart is one of the most commo...

"Tribbles" Protein Implicated in Leukemia

...cleus of many types of cells, and depending on the biochemical context, turns certain pathways on and others off. Pear and colleagues knew from fruit fly studies that the Tribbles protein was linked to cell growth and cell-fate determination and is closely related to the Tribbles gene in mammals. In fact, Tri...

Gastric Bypass Surgery May Lead to Increased Kidney Stone Risk

... the researchers obtained urine samples to measure biochemical risk factors for kidney stones. All patients had undergone the 'Roux-en-Y' procedure, which is the most common type of gastric bypass surgery. The same risk factors were measured in a group of 20 obese patients who were being evaluated for gastric by...

Good Heart Health May Begin With a Bar of Chocolate!

...aught us is that the chemical in cocoa beans has a biochemical effect similar to aspirin in reducing platelet clumping, which can be fatal if a clot forms and blocks a blood vessel, causing a heart attack." But this is by no means a blanket approval to simply binge on the sweet treat. "Eating a little bit of c...

Alternative Splicing - Molecular Cloning

...reviously identified as Nova binding sites through biochemical andx-ray crystallographic studies. The latter was in collaboration with Stephen Burley,a structural biologist of Rockfeller University. Unexpectedly, this search revealed four discrete peaks where the binding clusters locate. Furthermore, the locati...

Key Gene Controlling Eye Lens Development Identified

...ns will ultimately form in response to a series of biochemical signals. Following this systematic approach, the St. Jude team demonstrated that Six3 plays its important role in the PLE. The investigators also showed that a key consequence of removing Six3 during early development is that the PLE fails to undergo...

Some Prescriptions Can Lead to Chronic Drug-Induced Liver Injury

... factors and predictors of outcome.” Pre-defined biochemical criteria were used to recruit eligible patients with suspected DILI. Patients with previous liver and bone marrow transplants and those with acetaminophen toxicity were ineligible. To better understand the natural history of DILI, enrolled patients a...

Predicting the Dynamics of Clotting in Human Blood

...al reaction in each module instead of the 20-to-30 biochemical reactions that the modules represent. Surprisingly, this simple model adequately reproduced many features of blood clotting. "There’s a long history in chemistry of using simple models to understand more complex behavior," Kastrup said. "Instead of...

Eating Strawberries may boost memory

...ce the development of a basic understanding of the biochemical pathways involved in memory formation, the holy grail of CNS research in the pharmaceutical industry is the identification of a safe, orally active drug that activates memory-associated pathways and enhances memory," says lead author Pamela Maher, Ph...

Potential Target for Leukemia Treatment

...kemia. The paper describes detailed genetic and biochemical studies undertaken by researchers in the Division ...olving cell growth as well as specific genetic and biochemical steps. Disruption of this process is associated with diseases such as leukemia. RhoH GTPase is spe...

First Major Study of Mammalian “Disorderly” Proteis

...key roles in transmitting signals and coordinating biochemical and genetic activities that keep the cell alive and functioning. Kriwacki is senior author of a report on this work that appears in the prepublication online issue of Journal of Proteome Research. “Until now there was no way to separate IUPs in lar...

The Living Cell – Manufacturing, Protecting and Thrivin

...nds in a different way, viz. by means of a complex biochemical process which takes place in a special sub-structure of the cell's nucleus, known as the nucleolus.' These RNAs do not store information, being responsible for important tasks in 'assembling' the proteins. Importance for therapy The fact that RNAs ...

Researchers Uncover Critical Player in Cell Communication

...e discovery came after Desiderio and his team used biochemical “bait” to fish for candidate proteins that physically bind to TFII-I. The fishing expedition returned one protein known to control when and how much calcium a cell takes in. “The partner we found in the fishing experiment and the abundance of TFII-...

Study Unveils West Nile Virus Immune Evasion, Points to Vaccine Development

...ignals the JAK-STAT molecular pathway, a series of biochemical reactions essential for turning on immune-defense genes, allowing the body to clear out the virus. This process occurs normally in the African strain. Infection by the Texas strain, however, blocked IFNAR signaling activity, allowing the virus to r...

NRI Scientists find Potential Colon Cancer Weapon

...ocking this enzyme shuts down the toxic network of biochemical signals that promotes inflammation and colon cancer cell growth, the scientists reported in the latest issue of journal Cancer Research. They showed that blocking the production of aldose reductase halts the growth of human colon cancer cells impla...

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