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Tag: "binding" at medical news

Early detection of prostate cancer

... factor 1 (IGF-1) and insulin-like// growth factor binding protein 3 (IGFBP-3). Prostate cancer is the most common cancer in men over 55, but there is no single test that is sufficiently accurate to justify a program of screening all men in this age group. Current guidelines, set by the NH&MRC, advise tha...

Focus on DNA transcription

...cellular function.The discovery of this additional binding site will change the view of how transcription is...el of transcription.Knowing now that there are two binding sites on the enzyme instead of one will enable scientists to interpret data they collect much more a...

Iron is a two sided sword

...ore responsive to infection. Iron is vital for the binding and release of oxygen by red blood cells and iron deficiency is a relatively common health problem especially in younger women and older people with a poor diet. That is why many breakfast cereals are now fortified with iron, to make sure everyone g...

Beehives to curb caries

...at synthesize glucans from sucrose and promote the binding of cariogenic bacteria to teeth, critical steps in the development of decay. This natural substance is actually used by bees to strengthen and protect their hive from germs and foreign invaders. Worker honeybees collect propolis from the buds of va...

Mutation connected to Osteoporosis

...e 18 shared a GNAS1 mutation -- guanine nucleotide binding protein alpha stimulating activity polypeptide. GNAS1 controls a protein that plays a critical role in way cells function. In the case of POH, the GNAS1 mutation results in a mistaken signal to non-skeletal cells, which results in the creation of bon...

A new recovery for heart attacks

...w-oxygen conditions. These drugs would prevent the binding of hydroxyl groups to the HIF protein and in turn boost the amount of the protein around to improve oxygen delivery. The researchers have patented the asparagine-hydroxyl part of the HIF protein as a possible target for drugs, and will now look for ...

Blood test can predict pre-eclampsia

...low levels of a protein called SHBG or sex hormone binding globulin in early pregnancy. The protein is associated with insulin resistance, a condition that can sometime lead to diabetes. Both overweight and lean women who had the low levels of SHBG went on to develop pre-eclampsia. "It also may ...

DNA helps in cellular function

...cellular function.The discovery of this additional binding site will change the view of how transcription is...el of transcription.Knowing now that there are two binding sites on the enzyme instead of one will enable scientists to interpret data they collect much more a...

No explanation on schizophrenia gene

... applicable genetic explanation for schizophrenia, binding the case for new approaches to researching the illness. A paper by Douglas F. Levison and colleagues report that despite earlier findings to the contrary, there is no close link between schizophrenia and genes on the long arm of chromosome 1.// The ...

DNA transcription to be focused

...cellular function.The discovery of this additional binding site will change the view of how transcription is...el of transcription.Knowing now that there are two binding sites on the enzyme instead of one will enable scientists to interpret data they collect much more a...

Beehives to curb dental caries

...at synthesize glucans from sucrose and promote the binding of cariogenic bacteria to teeth, critical steps in the development of decay. This natural substance is actually used by bees to strengthen and protect their hive from germs and foreign invaders. Worker honeybees collect propolis from the buds of va...

New target for antidiabetic agents identified

...pression is increased under fasting conditions. By binding to Akt, TRB3 prevents the enzyme from being activated by insulin, leading to increased glucose output from the liver. Elevated hepatic levels of TRB3 RNA and protein were identified in diabetic mice compared with wild-type mice, the authors report. ...

Mouth Infection better handled with new discovery

...e cell to regulate its volume. It is said that the binding action of histatin acts like a foot in the door. Blocking the channel open allows a lethal unregulated flow of potassium and other essential molecules into and out of the cell. Now that the target for histatin has been identified, a better protein ...

New drug for mental alertness

...th more doses of medication. The new drugworks by binding to receptors in the brain called AMPA-type glutamate receptors. These activate the function of a neurotransmitter called glutamate and enhances the memeory. Because the drug effect only lasts for hours, they have relatively less side effects. The re...

Gold to be used for cancer detection

...ent in good concentration on the healthy cells. By binding the gold nanoparticles to the antibody of epidermal growth factor receptor, it is possible to make the gold nanoparticles attach themselves with the cancer cells. The gold nanopartcles are very good in scattering and absorbing light. Once the particl...

PET Scan find the Area of Brain Responsible for Anorexia Nervosa

...eir study. Since other studies have found reduced binding of these dopamine receptors in both people who are obese and those who have substance use problems, researchers Dr.Kaye and Frank hypothesized that they would find just the opposite in women with anorexia. The researchers also found increased dopami...

Ruboxistaurin (RBX) may prevent vision loss in diabetic patients

...inase C. Moreover, RBX was found to be specific in binding only to the a-form of PKC. Though, RBX does not prevent the progression of diabetic retinopathy, it reduces the vision loss which is caused by macular edema. RBX in the study group did not produce any side-effects. ...

New clues to maternal aggressive behavior

...und out that the functions of the hormone receptor binding in the central amygdala reduces the levels of anxiety and promotes dominant social behavior in females. Reference: American Physiological Society's 2005 Conference, July 2005...

Researchers Discover Protein That Causes Malaria

...ch malaria parasites invade red blood cells is the binding of a protein on the surface of merozoites called E...(from liver cells) into the bloodstream. Thus, the binding of EBA-175 to glycophorin A is a prominent target for the development of therapies to control malari...

Identified Protein To Inhibit Cell Migration

...udy indicates that CIB1 inhibits cell migration by binding to and activating a protein called PAK1, or p21-activated kinase, in cancer cells. When CIB1 activates PAK1, this kinase then inhibits cell migration by adding a phosphate group to a host of other proteins in the cell. Thus, the study suggests that...

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(Date:8/28/2014)... Yale University researchers have identified a handful of bacterial ... as Crohn,s disease and ulcerative colitis, using patients, own ... are published Aug. 28 in the journal Cell ... intestinal microbiota, which plays a critical role in the ... only a small number of bacterial species affect a ...
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