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Tag: "bind" at medical news

Role Of MicroRNAs In Angiogenesis Researched

...endell, an "anti-sense" version of miR-17-92 could bind to miR-17-92, thereby canceling its effects. If it is possible to deliver "regular" miR-17-92 to increase angiogenesis, as was demonstrated in the Nature Genetics paper, it may be possible to deliver anti-sense miR-17-92 to decrease angiogenesis and ...

Single Sugar Enables Antibody to Treat Inflammation

...uired for its protective ability. IgG antibodies bind to and activate specific immune cells, with different forms or "subclasses" binding to specific receptors (called Fc receptors) on the immune cell's surface. Antibody subclasses have different abilities to induce inflammation in the body by virtue of...

Structure of DNA-modifying enzyme In Small Pox Determined

...plex has been long-awaited." DNA-modifying enzymes bind to specific sequences in the genetic code to aid in the many steps of DNA replication. The smallpox virus is one of the most easily transmissible infectious diseases known to humans, resulting in up to 30 percent mortality. The efficiency, with whic...

Penn Researchers Throw Light on the Structure Of Smallpox Virus Protein

...plex has been long-awaited." DNA-modifying enzymes bind to specific sequences in the genetic code to aid in the many steps of DNA replication. The smallpox virus is one of the most easily transmissible infectious diseases known to humans, resulting in up to 30 percent mortality. The efficiency with whi...

Scientist Discovers Crucial Part of Blood-Clotting Process

...many places where enzymes and other substances can bind to activate or stop biochemical reactions in the cell. By revealing how factor IXa works, it should be possible to make synthetic chemicals that prevent strokes and heart attacks, Dr. Neuenschwander said. Conversely, you could make synthetic activa...

Biological Basis Behind a Couch Potato

...y respond more to orexin," she said. Orexin must bind to receptors in the brain to produce increased activity, so the researchers reasoned that the lean rats must have more orexin receptors. When they did a blind analysis of the brains of obese and lean rats of various ages, they found that the lean rat...

High-Fat, Copper-Rich Diets Associated with Increased Rates of Cognitive Decline

...nts with Alzheimer’s disease, and medications that bind with copper to block its effects have shown promise treating patients with the condition. “This finding of accelerated cognitive decline among persons whose diets were high in copper and saturated and trans fats must be viewed with caution,” the au...

Ordinary Heparin as Effective as Expensive Blood Thinner

...lecules which would mean that it is less likely to bind to a protein in the body making it presumably more predictable and convenient to use. The injection is to be administered only once a day, and this can be done by the patient. However a study by McMaster University researchers revealed that a weig...

Monoclonal Antibody based system for Anthrax detection

...rface molecule of Bacillus anthracis. They did not bind to other bacteria closely related to B. anthracis. Seeberger hoped that a highly sensitive anthrax diagnostic system and new vaccines would be based on this new antibody. "I think it would be very useful and it could be important for testing agains...

Replacing Old Mattress, Adding Ventilation Reduces Mites

... cat allergens, possibly because cat allergens can bind to the smoking-related particulate matter, and consequently, allergen concentrations might be increased in settled dust. (Source: Neswise)...

Protective Intestinal Antibiotic Protein Discovered

..., belongs to a protein class called lectins, which bind to sugar molecules. These particular lectins' seek-and-destroy mission may help to create an "electric fence" that shields the intestinal surface from invading bacteria, Dr. Hooper said. The findings of this study may offer researchers new clues a...

Researcher Hits Bulls-Eye for Antibiotic Target

...them as well." Researchers could design drugs to bind to the protein and keep it from being used by the bacteria, rendering the bacteria unable to react to and survive a lack of nutrient supply; the other possibility would be to design a drug to mimic the protein, causing the bacteria to react as if it ...

Scientists Review Loeys-Dietz Syndrome in the Largest Ever Study to date

...taR2. The two TGF-beta receptors act together to bind TGF-beta, a family of signaling molecules that controls cell growth, movement, activity and death by controlling whether certain genes are turned on or off. TGF-beta receptors normally are found on the cell's surface, facing the outside of the cell, ...

Inhibitor That Blocks Host Receptors Found To be Effective In Treating Anthrax

...he researchers said that the inhibitor was able to bind to multiple sites on the host receptor making it much for potent than the inhibitors that binds to single site. The researchers found that the new approach led to a 50,000-fold increase in activity to block multiple binding sites when compared with ...

A Glass of Orange Juice To Keep Recurrence Of Kidney Stones At Bay

...using minerals and other chemicals in the urine to bind together. Over time, these crystals combine and grow into a stone. In the UT South western study, 13 volunteers – some with a history of kidney stones and some without – underwent three phases, each lasting one week. Chosen in random order, the pha...

Malarial Parasite Hides In Placenta

... Uganda. 'Most of the parasites we studied could bind to three different receptors in the placenta,' she...proteins or if one and the same protein is able to bind to many host receptors. Source-Eurekalert RAS...

Protein Molecules in blood predict preeclampsia development

...ng VEGF in the bloodstream. The surplus VEGF would bind to the high levels of sFlt1 produced during preeclampsia, but enough free VEGF would still be available to attach to cell surface receptors to promote the health of blood vessels. Dr. Levine cautioned, however, that such attempts to develop a drug ...

Key component of sunscreen heals sunburn and prevents skin cancer

...best way to do this is using chelators, drugs that bind and export iron from the body. “However, long term use of chelators can be toxic for cells as it starves them of the iron necessary for normal biological processes, for example the red blood cells that transport oxygen around the body need iron to...

Cure for food allergies is less than a decade away

...change the molecules so that IgE antibodies do not bind to the allergen any more." "If we can fool the immune system in such a way that we can mimic chronic exposure by taking microbial or parasitical factors and adding them, then we might be able to shorten the treatment," he said. There was a decrea...

Virus Can Mutate lethally With Help Of Carbohydrates

... more deadly strain of the virus actually does not bind as tightly. We're not sure why, but it may be because it can more easily let go and get into the cell to cause disease. It's not giving the body the time to mount an immune response.”The scientists were of the opinion that on understanding as to how ...

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