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Tag: "bind" at medical news

Dark chocolate can help ease symptoms of diarrhea

...ientifically established that cocoa flavonoids can bind to and inhibit a protein called CFTR, which regulates fluid secretion in the small intestines. Children younger than the age of five and the elderly are the most likely to develop grave health problems if their condition leads to dehydration. In se...

Breast feeding can prevent HIV infection transmission

...e on this factor. Other major milk proteins do not bind to DC-SIGN nor inhibit viral transfer. These results demonstrate that protein associated Lewis X is necessary and sufficient to interact with DC-SIGN and block the interaction of DC-SIGN and HIV. The identification of a factor in human milk that ca...

Leeches Provide Clues Regarding The Prevention Of Heart Disease

...ical leech Hirudo medicinalis for their ability to bind to molecules called serine proteases. These molecules have the ability to prevent coagulation or clotting of blood. Of the nearly 2,000 molecules the researches screened, more than 75 of them interacted specifically with the fixed target and 16 of ...

Alzheimer's a new type of diabetes: Study

...nd its related protein IGF-I lose their ability to bind to corresponding cell receptors, creating a resistance to the growth factors and thus causing cells to malfunction and eventually die. The authors stress that this could have important implications for treatment of this disease, and that being able...

Protein Linked To Accelerating Rheumatoid Arthritis

...flammation. The researchers found that CII did not bind in the blood samples of RA patients. But 45 percent of the RA blood samples formed immune complexes with the altered form of the protein. The researchers say that CII serves to accelerate and already worse condition in RA. "Our study has important im...

Initial Steps In Spread Of Cancer Identified

...plant and nurture them. It causes them not only to bind but to proliferate. Once that all takes place we have a fully formed metastatic site or secondary tumor," said Lead researcher Dr David Lyden. He added that for the first time the initial steps involved in metastasis were mapped out. "By blocking bon...

Nicotine Vaccine May Help Smokers To Quit Smoking

...id works by producing antibodies that specifically bind to nicotine, and thereby prevent much of the nicotine from entering the brain, reported the health portal HealthDayNews. This process potentially reduces the pleasurable effects from smoking and reduces the addiction to nicotine, it said. The vaccin...

Small Biosensor To Enable Cancer Detection

...oteins, which cause the cancer-specific markers to bind to the surface. The discs are created in a silicon wafer and made to vibrate electronically in two modes. When a cancer-specific marker binds to the surface of a disc, in the pattern of the coating, the uneven weight causes one of the modes of vi...

Coffee Reduces Risk of Breast Cancer in BRCA1 Mutation Carriers

...arity to endogenous estrogens and their ability to bind to estrogen receptors," the authors concluded. The protective effect of coffee was thought to be because of the phytoestrogens present in it....

Metastasis of Neuroblastoma linked to Loss Of Caspase-8 gene

...und Integrin molecules are free and when caspase-8 bind to it results in Integrin-mediated death (IMD). By this technique all the free and moving cancerous cells are destroyed by the Integrin molecules before they can affect another distant organ. The research team conducted experiments using tumor cell...

Multiple Sclerosis Can Be Treated By Blocking Fat Hormone

...ibodies or a form of the leptin receptor unable to bind leptin, either before or after disease onset improved clinical symptoms of disease, slowed disease progression, reduced disease relapses, and reduced the number of antigen-specific T cells. The authors delved further to unravel the cellular signal...

Tumor Suppressor p53's Contradictory Regulatory System

...USP. Hu and his team found that both p53 and MDM2 bind on the same location on HAUSP. They also report that this was possible by conserving a “short amino acid signature" The reseraches arrived at the conclusion that p53-MDM2 pathway is regulated by HAUSP. These findings provide researchers with potentia...

Understanding the RNA binding protein and its functions inside the cell

...s being done to identify RNA-binding proteins that bind RNAs of interest such as those involved in the targeting, degradation, and translation of RNAs into proteins. This will help them to identify those RNAs which play a role in the disease process....

Non-Coding RNA Vital For Gene Activation And Protein Expression

...w certain epigenetic activators, in this case Ash1 bind to the target DNA molecule to facilitate the activation of certain genes that play a crucial role in determination of cell function. The mechanism of recognition of a specific DNA sequence (target gene) by the epigenetic factors followed by binding a...

Anticancer Properties of Vitamin D Could Be Separated From Other Functions

...t alopecia but which still allowed beta catenin to bind to the vitamin D receptor.” If indeed a drug highlighting the anti-cancer property of the vitamin can be developed, it could be useful in early stage cancers, but not in advanced or terminal cancers, “That’s because we know that by the time colon can...

Anticancer Properties of Vitamin D Revealed

...t alopecia but which still allowed beta catenin to bind to the vitamin D receptor,” he said. This suggested to the researchers that it may be possible to separate the anti-cancer role of vitamin D from its effects on bone and calcium.If a drug mimic of vitamin D can be developed, it could prove useful in ...

GlaxoSmithKline Agrees To Settle Paxil Claims For $14 million

...rprise to keep the generic producers of Paxil in a bind of using frivolous patent-infringement lawsuits, thus managing to keep the cost of the drug in the high range. However, even after reaching the agreement, GSK denied the allegations, "We made the decision that settling was appropriate to avoid the ex...

Researchers Identify The Cause To Obesity

...difficult, or it may be that as a package it can't bind to leptin receptors in the brain," suggested Dr. Zhao. Dr. Zhao and his collaborators sought to find factors normally circulating in blood that could inhibit leptin. CRP was the most potent of the five serum leptin-interacting proteins they identi...

Receptor for H.pylori Identified in Stomach

...nized hosts are free-living, but approximately 20% bind to gastric epithelial cells. This binding induces an immune response and alters the morphology and behavior of the epithelial cells due to injection of bacterial proteins into the cells. This interaction can lead to peptic ulcer disease, gastric aden...

Nanotechnology Could Revolutionize Cardiac Treatment

...xidized LDL for a macrophage's attention. The NLBs bind to receptor sites on macrophages, cutting the accu...and closely analyzing which forms of the particles bind to the different macrophage receptors,’ Uhrich said. ‘The significant finding of our study is that t...

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