A New Therapy to Protect Cancer Patients Against Infertility
...dy had shown gonadotropin-releasing hormone (GnRH) antagonists were likely to be able to protect the ovary in wom...ses within 12 months. We believe that using GnRH antagonists in this way could reduce the side effects of chemotherapy over a long period, said Dr. Stern. Other ...20 Mg Rimonabant Per Day may Help to Quit Smoking
... the cannabinoid 1 receptor. These CB1 receptor antagonists could therefore form part of a therapeutic program...see whether there was evidence that these receptor antagonists work two Cochrane Researchers, Kate Cahill who works at the Department of Primary Care in the Univer...Stressed Mice may Hold Clue to How Fat is Stored: Study
...s, using the results of our research, will develop antagonists against the Y2 receptor that will bring about a reduction in fat cells." Georgetown professor Stephen Baker, who co-authored the study, meanwhile pointed out that the ability to add fat selectively would be useful for cosmetic restructuring, like f...Blocking the Y2 Receptors can Prevent Obesity
...s, using the results of our research, will develop antagonists against the Y2 receptor that will bring about a reduction in fat cells....Doctors in UK Promoting Awareness of Gastro-oesophageal Reflux Disease
...counter medications such as antacids and histamine antagonists (drugs to counter histamines). Histamines are chemicals found in plant and animal tissue and released from certain type of cells as part of an allergic reaction in humans. It stimulates gastric secretion and causes dilation of capillaries, constric...New Method For Fighting Leukemia
...s group, regimens combining such agents with Bcl-2 antagonists like ABT-737 could represent a particularly effective treatment strategy in leukemia and various other malignancies. This work was supported by grants from the National Institutes of Health, the Leukemia and Lymphoma Society of America, and the D...Combination Therapy More Effective for Treating Lower Urinary Tract Symptoms
... not respond to monotherapy with either ?-receptor antagonists or antimuscarinic agents. Treatment with tolterodine ER plus tamsulosin resulted in statistically and clinically significant treatment benefit. Similarly low incidences of acute urinary retention were observed in all treatment groups, and there were ...Protein Increase Decreases Risk of Heart Failure
...ecule that can regulate its expression. "Perhaps antagonists that act on Gq-coupled receptors, which are being used clinically for heart failure, may be part of the mechanism of action in heart failure, which is why they appear to give beneficial results. They prevent further S100A1 decreases through this mech...Enhancing Infants Immune System
...6) when TLRs are stimulated. When Levy's team used antagonists to inhibit adenosine's activity, newborns' white blood cells produced normal, adult levels of TNF-alpha in response to bacterial and viral triggers. "In the future, we could try to block adenosine in newborn animals to see if this helps protect again...Alzheimer’s disease trial With EVT 101 For Successfully Complete
...nding is of great importance as non-selective NMDA antagonists have unfavourable side-effect profile.The EVT 101 ...However, the clinical development of non-selective antagonists has been limited by unfavourable side-effects, such as hallucinations. In the early 1990's it was fo...Inhibition of morphine tolerance by spinal melanocortin receptor blockade
...involved in the mechanisms of opioid tolerance and antagonists of this receptor may be a possible new target in t... in spinal neuronal plasticity. The specific MC4-R antagonists would be promising compounds to alleviate the side effects of long-term morphine treatment. Their ab...Heart Patients More At Risk Get Fewer Medicines
...s, ACE inhibitors or ARBs, and beta-adrenoreceptor antagonists were evaluated according to predicted risk of deat...percent more likely to receive beta-adrenoreceptor antagonists compared with high-risk patients. In conclusion the researchers had said that the predicted and obs...Angioplasty plus stenting better than thrombolysis for elderly patients with AMI
...racoronary stents and use of glycoprotein IIb/IIIa antagonists were routinely employed. Therefore, Dr. Hanoch Hod, of Chaim Sheba Medical //Center in Tel Hashomer, Israel, and associates followed 130 consecutive patients aged 70 or older treated for ST-elevation AMI. Eighty-six patients were admitted to one cen......volved about 52,000 women who were taking dopamine antagonists and 55,000 women who were not. The two groups were... incidence. Animal studies have suggested dopamine antagonists can raise blood levels of prolactin, which has been shown to promote tumor growth in rats. However, ...