Tag: "analogs" at medical news

UCLA Researchers Discover Link Between Parkinsons and Narcolepsy

...n's disease patients with hypocretin or hypocretin analogs may reverse these symptoms. More than 1 million people in the U.S. have been diagnosed with Parkinson's disease, and approximately 20 million worldwide. (The percentage of those afflicted increases with age.) Narcolepsy affects approximately one i...

UIC Researchers Receive $2.1 Million Grant

...entified some potent GSK-3 inhibitors by screening analogs of staurosporine, a natural product that is able to block a number of protein kinases. Some of these compounds are able to protect nerve cells in the test-tube and block mania in animals, he said. "Other members of this chemical series have recentl...

New Method For Fighting Leukemia

...d potentially other malignancies.' 'For example, analogs of roscovitine have recently entered the clinic, and a number of other agents capable of reducing Mcl-1 levels in tumor cells are currently being developed,' he said. Based upon the findings of Grant's group, regimens combining such agents with Bcl...

Anti Cancer Drug from Blue Green Algae

...hetic route to natural product compounds and their analogs is often an essential step in drug development. Wi...cryptophycin natural products, including important analogs with clinical potential. This included characterization of an enzyme, cytochrome P450, that always i...

Estrogen Curbs Appetite In Same Way as the Hormone Leptin

...m, obesity in particular. “Brain-specific estrogen analogs would allow us to take advantage of estradiol’s weight reducing effects without altering peripheral tissues such as the breast and ovaries,” said Horvath. Source: Yale Universty SRM...

Estrogen Curbs Appetite: Research

...m, obesity in particular. "Brain-specific estrogen analogs would allow us to take advantage of estradiol's weight reducing effects without altering peripheral tissues such as the breast and ovaries," said Horvath. Source-Eurekalert SRI...

Surgery or IUD for Heavy Periods

...bleeding include birth control pills, progesterone analogs and nonsteroidal anti-inflammatory drugs. The IUD that was evaluated in six of the eight trials in this review — the levonorgestrel intrauterine system, or LNG-IUS — has been in use in Europe for more than a decade and was approved by the U.S. Food a...

Pain-killer Drug Can Help Fight Breast Cancer

...ted deaths. The researchers took several of these analogs and in laboratory cultures, tested their effects o...tested them on human placental cells to see if the analogs would stop aromatase production in these cells. They found that the analogs stopped aromatase produc...

Novel Technique For Targeting Small-Cell Lung Cancer

...of endoscopic imaging. Conjugation of somatostatin analogs with fluorescent agents enables tumor detection by optical imaging techniques including endoscopy. The main advantages of this method are high sensitivity and outstanding spatial resolution. In a recent work, researchers from Israel used novel backb...

HIIP- A Novel Inhaled Insulin Delivery System As An Alternative To Injectable Insulin Therapy

... like human regular insulin or fast-acting insulin analogs such as insulin lispro. A recent study, published in the October issue of Diabetes Care, evaluated the key performance features of a novel inhaled insulin delivery system -- human insulin inhalation powder (HIIP) -- based on AIR particle technology a...

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