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Tag: "amino" at medical news

Male Contraception: Discovery Stirring Interest Among Scientists, Drug Developers

...found that SFEC has extensions at both ends of its amino acid sequence. Other ATP/ADP carriers do not have these extensions, which may explain why SFEC is able to perform its shuttling function in the distal sperm tail. “The distal sperm tail does not have mitochondria, which means that SFEC operates in...

Mayo Researcher Discovers Target Site for Developing Mosquito Pesticides

...cular design at Mayo Clinic, identified two unique amino acid residues called cysteine (286) and arginine (... by crippling the serine residue, which is another amino acid of the enzyme acetylcholinesterase and is located at the active site of the enzyme. This serine...

Structure of Iron Regulatory Protein-RNA Complex Solved

...RP1 is a very large protein, composed of about 900 amino acids arranged into four major domains. "We expected that IRP1 would open up the two major domains facing each other along a hinge, rather like a clam shell, to accommodate the RNA binding," Walden said. "What we didn't expect was that that opening...

MIT Creates 3-D Scaffold for Growing Stem Cells

...neering, is a pioneer in coaxing tiny fragments of amino acids called self-assembling peptides to organize ...s. Adding motifs With the addition of defined amino acid fragments called active motifs, the scaffold can be fashioned to coax stem cells to behave in c...

Scientists Come Up With A Powerful Weapon To Fight Drug Resistant Bacteria

...acid chains and the sequence of positively charged amino acids, they were able to create an array of weapon... peptides (protein fragments) to contain only four amino acids, as opposed to the 12 - 50 found in their natural forms. These findings will hopefully open...

A Study Explores the Medical Potentials of Bucky Amino Acids

...imal skin that was exposed to buckyball-containing amino acids. "Our results confirm that repetitive motio...ssage of nanoparticles through the skin." 'Bucky amino acid' penetrates faster, deeper when skin is flexed and penetration was also found to be deeper afte...

Nanoparticle Uptake Zoom by Repetitive Motion

...basis of the research. These bucky balls contained amino acids. Experiments showed that amino acid penetrated deeper and faster with the increasing degree of flexing of the skin. . "Our resul...

Higher Folate Levels Linked to Reduced Risk for Alzheimer’s Diseas

...s. Researchers suspect that elevated levels of the amino acid homocysteine in the blood, which is linked to a higher risk for cardiovascular disease and stroke, may also increase the risk for Alzheimer’s disease. Folate, vitamin B12 and vitamin B6, are important in the body’s processing of homocysteine—the...

Early Risers are Born That Way, Not Made

... condition. According to them, replacement of one amino acid from among hundreds found in a protein can result in irregular sleep patterns. Ptacek's group has determined how the gene causes the condition, by transplanting the gene into mice to create rodents with FASPS. "They get up and start running on...

Fall Back on Folic Acid to Improve Cognitive Abilities

...f reduced levels of folate, and elevated levels of amino acid homocysteine, in the blood of older adults which restricts cognitive ability, increasing the risk of dementia. To fully comprehend the benefits of folic acid, Dutch Scientists, conducted a study of 818 men and women who portrayed elevated leve...

Buckyballs Used as 'Passkey' into Cancer Cells

...lleagues developed contain a molecule called Bucky amino acid that was created in Barron's lab. Bucky amino acid, or Baa, is based on pheylalanine, one of the 20 essential amino acids that are strung together...

VBI Provides Potential Targets to Diabetes Therapeutics

...." The group investigated the roles of three key amino acid residues and, more specifically, examined how changing each residue affected the enzyme's properties. The researchers concluded that it is possible to influence the activity of the enzyme from a site distinct from where the reaction takes place ...

Research on Human Metabolic Disorders

...e hundreds of human disorders in the metabolism of amino acids, carbohydrates, lipids, minerals, and other molecules. It also is intended to be used in the future to study metabolic variations between people as a way to individually tailor diet for weight control. Studying the metabolism of cholesterol i...

Man-Made Proteins Could Be More Useful Than Real Ones

.... Researchers have constructed a protein out of amino acids not found in natural proteins, discovering t...ct them. To biochemists, a protein's chain-like amino acid sequence is considered its primary structure. Its secondary structure is produced when this cha...

Bacteria Fighter Goes Where Antibiotics Can't

... peptide, a small molecule made of short chains of amino acids that attacks Pseudomonas aeruginosa. P a... normal red blood cells. The number and order of amino acids in an antimicrobial peptide determines how it recognizes and attacks an invading microbe. Some...

Are Oysters Really Aphrodisiacs?

...ncludes oysters - and found they were rich in rare amino acids that trigger increased levels of sex hormone...erformance liquid chromatography to identify which amino acids were present and in what quantities. They found two unusual ones - D-aspartic acid (D-Asp) and...

Computer Tool Helps Pinpoint Risky Gene Mutations

...in the general population. This mutation caused an amino acid residue change in the protein produced by the...lutionary history, looking at how long the changed amino acid residue position has been preserved in various organisms. The last category is important becaus...

Specially Treated Prawns for Seafood Allergy Sufferers

...on damages the proteins, revealing hidden reactive amino acid residues. Subsequent heating then destroys the exposed residues. 'Radiation and heat seems to be a promising method for reducing the immunoreactivity' say the researchers. Samuel Lehrer of Tulane University in New Orleans, USA, is already work...

Common Ingredient in Big Macs and Sodas Can Stabilize Gold Nanoparticles for Medical Use

...er," Amiji said. The new generation of trimeric amino acids peptides discovered by Katti in 1999 (referred to by Amijii as 'Katti Peptides') have provided a solid chemical platform and have become sources of a number of other discoveries. Their applications in the development of drugs for Wilscons' dise...

Rare Mutation Causes Early Heart Disease and Metabolic Syndrome

... certain forms of cancer. The mutation changed one amino acid in the protein, which the team showed altered the activity of the protein encoded by LRP6. “The reason for the observed association of multiple risk factors with one another has been a mystery,” Lifton said. “Our findings have implicated the W...

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