Tiniest Nanoscale Test Tubes Corked; Holds Promise In Cancer Treatment
... ‘cork’ the test tubes, the researchers applied an amino chemical group to the mouth of the tubes and an aldehyde chemical group to the corks. The two groups are complementary, so they bond with one another. Billions of nanotubes could fit on a postage stamp and therefore, ‘we do not put individual caps ...Study Highlights Appetite Regulation Pathway, New Hope for Weight Loss
...mTOR pathway is very sensitive to ‘branched-chain’ amino acids, particularly leucine, Dr. Seeley explains. ...olic processes, animals ate less. Other, similar amino acids did not give the same results. This animal study, says Dr. Seeley, could eventually have imp...Link Between Immune System And Nervous System
...receptor, the other a shortened version with fewer amino acids. When the researchers added substance P to cell cultures with the receptors, both responded with an increase in calcium ions, but used distinct signaling pathways. The truncated NK-IR did not respond directly to substance P, but worked throug...Finnish research: Cysteine Chewing Gum as a cure for cancers of the mouth
According to a Finnish research it was found that amino acid, l-cysteine can prevent oral cancers. In the developed countries about 80 % of the cancers occur// in the mouth, pharynx and oesophagus. The main causative agent is smoking and alcohol drinking. This results in a strong exposure of the upper dig...Transport of Proteins Unravels the Mystery behind Neurodegenerative Diseases
... of part of a gene that encodes repetitions of the amino acid glutamine in the protein. Although different genes are affected, all of the polyglutamine-expansion or "polyQ" diseases are characterized by symptoms that begin in middle age and by the loss of certain types of neurons through a pattern in which...Treatment of Bacterial Infection Paves the Way to Treat CF Infection
...partment chair John Mekalanos, recognized that the amino acid sequence of Hcp1 in PA closely resembled that of Hcp1 in Vibrio cholerae. The Mekalanos lab had previously discovered that the Hcp1 protein of V. cholerae is released from the bacterium via a novel secretion pathway. Because Hcp1 proteins from b...Transporter offers reliable clues for safer pain medicine
...y says. He’s already testing naturally occurring amino acids and peptides and found one – lysine, an essential amino acid vital to good growth and found in high concentrations in red meat, cheeses, poultry, sardines, ...Folic Acid Supplements to Prevent Cancer
...itating a variety of reactions in nucleic acid and amino acids metabolism. Some of which are critical to healthy life, such as DNA synthesis, DNA repair, and converting homocysteine to methionine. The latter is particularly important because excess homocysteine is linked to chronic health problems, such as...Indian Scientists Identify Cataract Causing Genes
...nd that in this case the replacement of Lysine, an amino acid, with Arginine was found to ultimate lead to Cerulean cataract. He also stated that, the two genes, along with a newly discovered third, have been localized to Indian families. Singh said that congenital cataract affected about three per 10,00...New Molecular Treatment Identified To Treat Blood Cell Cancers
...enter have identified a peptide (short sequence of amino acids // . The speciality of this discovery is that the peptide is found to have high affinity, stability and specificity towards leukemic and lymphoma cells. Hence researchers say that this discovery can be used to image tumors and deliver anti-canc...Bioinformatics Made a Boon In Immune Response Study - LIAI Finds
...nes will initiate an immune response. Peptides are amino acid pieces that potentially can be recognized by the immune system. ‘There are literally thousands of peptides,’ explained Sette. ‘You might have to create and test hundreds or even thousands of them to find the right ones,’ he said. ‘With bioinform...Consumption of an Egg per day Could Prevent Heart Disease, Cancer
.... It is the essential nutrients in eggs, such as amino acids, vitamins and minerals that may be responsible for this protection. Eggs are also low in calories - a large egg contains only 75 calories and 5 grams of fat - and other research suggests they can help you lose weight. Health experts used to...Scientists Discover Non-dietary Therapy For Celiac Diseases
...lutamine residues, which comprise one-third of all amino acid residues in gluten." Dr. Khosla's group used recombinant bacteria to produce a form of EP-B2 that only activates under acidic conditions similar to the conditions found in the human stomach. The researchers demonstrated that EP-B2 efficiently ...Abnormal Abeta - Protein Level in Human Brain Trigger Alzheimer's Risk
... drip, scientists give test subjects a form of the amino acid leucine that has been very slightly altered to label it. Inside the leucine are carbon atoms with 13 neutrons and protons in their nucleus instead of the more common 12 neutrons and protons--in scientific parlance, carbon 13 instead of carbon 12...Scientist Optimistic In Breakthrough For Causes Of Neurodegenerative Diseases
... biomarker is known as nitrotyrosine, made when an amino acid in the brain, tyrosine, is in the presence of an oxidative-stress molecule called peroxynitrate. The biomarker was found on 31 sites along 29 different proteins, half of which had been previously implicated in several of the neurodegenerative di...'Diet Modifications' - less effective against Stress
...d to a decrease in lipoproteins and an increase in amino acids, glucose, lactate, creatine and citrate. The stress caused by the water avoidance resulted in increased levels of O-acetyl glycoproteins. Giving the rats the LC-PUFA enriched diet did help to improve their metabolic profiles, an indicator of ...Genetic Mutation in Mice Suggests Extinct Mammoth Had Light and Dark Fur
...on, these two studies are striking examples of how amino acid changes in structural proteins can also be important,” says Hopi Hoekstra, an assistant professor of biology at UC San Diego who headed the team that discovered the genetic roots of the color differences in Florida’s mice. The coat pattern and...Cell Survival Depends on Chromosome Integrity
...ones. The acetyl groups are added to lysine-56, an amino acid in the histone protein chain. Chromosomes in yeast cells missing Hst3p and Hst4p become hyperacetylated on lysine-56 — it appears that every lysine-56 in every histone has attached an acetyl group. “This is the first time we’ve ever seen such ...Prion Disease Agent Causes Heart Damage
...ally the glycophosphoinositol anchor, a stretch of amino acids at the COOH end of the protein-between the membrane of cells and the prion protein. By taking off this anchor, the researchers showed that the prion protein still folded but was no longer able to attach in normal amounts onto the surface of cel...Mutation in the Envelope Gene May Be the Reason for the Development of HIV Linked Cognitive Decline
...lai. They found such a pattern, consisting of four amino acids, within a subregion of the viral envelope gene known as the V3 loop. ‘The identification of these signature mutations presents convincing evidence that HIV adapts to the local environment within the central nervous system and, moreover, that ...