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Tag: "alters" at medical news

Just One Cigarette can Cause Nicotine Addiction

.... "Laboratory experiments confirm that nicotine alters the structure and function of the brain within a day of the very first dose. In humans, nicotine-induced alterations in the brain can trigger addiction with the first cigarette," commented lead researcher Dr. Joseph R. DiFranza, Professor of Family M...

Gene Variation Increases the Risk of Lung Cancer

... and Genetics. Essentially, sustained inflammation alters the microenvironment of the lung tissue, damaging cells and altering DNA. Inflammation is part of the immune systems arsenal to combat the effects of infection and cell damage. However, prolonged or intense inflammation could lead to conditions wit...

Genetic Mutation That Makes Common Cancers Resistant to Drugs Identified

...reast, colorectal and ovarian cancer. The mutation alters the electrostatics of binding pocket in the pleckstrin homology domain, the portion of the enzyme that docks with phospholipids on the cell membrane," said Dr. Kerry L. Blanchard, Executive Director, Discovery Biology Research, Eli Lilly and Compan...

Prions Capacity can Be Aggrevated by Solid Particles

...f uptake of the agent, or that the mineral somehow alters the size of prion aggregates, which have been shown to be more infectious than prions alone. Aiken emphasizes there's still much to learn about routes of prion transmission, and the role of soil is just beginning to be explored. "Soil is a very com...

Smoking Linked to Lower Parkinson's Disease Risk

...rvival of dopaminergic neurons; or cigarette smoke alters the activity of metabolic enzymes or competes with other substrates for these enzymes and thereby alters the production of toxic endogenous (dopamine quinones) or exogenous (MPP+) metabolites," the authors...

20 Mg Rimonabant Per Day may Help to Quit Smoking

...ergy balance and food intake. Over time the body alters the nature of its energy mechanism to compensate for this effect. Stopping smoking removes the nicotine and once again disturbs the mechanism, adding to the withdrawal symptoms and leaving a person prone to put on weight. One potential way of preven...

Gene Therapy Awakens the Brain Despite Blindness from Birth

...onal view is that blindness in infancy permanently alters the structure and function of the brain, leaving it unable to process visual information if sight is restored. We've now challenged that view," he added. According to the researchers, the new findings are significant because they support the potent...

First Gene Linked to Scoliosis Identified

...esearchers speculate that this particular mutation alters the binding of a molecule that controls whether the gene is turned on. They think the gene is turned off more often than it should be, which reduces the amount of CHD7 protein produced. "The change in the amount of the protein produced is subtle, w...

Very Soon You can Eat to Your Hearts Content

...ce that causes production of ACAT2, an enzyme that alters the molecular structure of cholesterol so that it can be transported to the bodys cells. Lawrence Rudel, Ph.D., a professor of comparative medicine, said that the study raised hope for humans. "We deleted an enzyme in mice and they could eat any...

Combining NSAIDs With Chemotherapy May Improve Cancer Therapy

...next stage. The UI research found that celecoxib alters the expression of G1 checkpoint proteins and significantly decreases the activity of a protein called E2F1. This activity is required for cells to move through the cell cycle and also is crucial for S phase activities like DNA repair. Celecoxib's inh...

Recurrent Gliomas: Vorinostat Shows Anti-cancer Activity

...t help organize the structure of DNA -- vorinostat alters the expression of several important genes and proteins resulting in tumor cell death and stopping tumor growth. Dr. Galanis says that study findings indicate that vorinostat by itself shows anti-cancer activity in glioblastoma multiforme. Plans are...

Second Hand Smoke Has Serious Consequence on a Childs Heart

...to dilate. Even modest exposure to tobacco smoke alters endothelial function in children, and may impact early development of atherosclerosis (hardening of the arteries)," study lead author Dr. Katariina Kallio, a research fellow at the Research Centre of Applied and Preventive Cardiovascular Medicine at ...

New Light on Working of Brain Networks

...idence of a// molecular mechanism that dynamically alters the strength of higher brain network connections. This discovery may help the development of drug therapies for the cognitive deficits of normal aging, and for cognitive changes in schizophrenia, bipolar disorder, or attention deficit hyperactivity...

Brain Networks Strengthened by Closing Ion Channels

...idence of a molecular mechanism// that dynamically alters the strength of higher brain network connections. This discovery may help the development of drug therapies for the cognitive deficits of normal aging, and for cognitive changes in schizophrenia, bipolar disorder, or attention deficit hyperactivity...

Environmental Factors Linked to Increased Risk of Breast Cancer

... is tagged by a molecular "methyl" fragment, which alters activation of the genes. In this instance, the researchers looked at global hypomethylation – aberrant methylation throughout the entirety of a person’s DNA. The researchers found differences in global DNA hypomethylation depending on breast canc...

New Research on the Effects of Smoking and Coffee on Parkinson's Disease

...bout cigarette smoking and consuming caffeine that alters the biology underpinning of Parkinson's disease." This research is still in a nascent stage. Therefore the research findings are not to be interpreted as a blanket prescription to prevent Parkinson’s disease....

Research Explains How Lead Exposure Produces Learning Deficits

...new neurons (neurogenesis) in the brain. Lead also alters the normal development of newly born neurons in a ...lead decreases neurogenesis in the hippocampus and alters the ability of these new neurons to communicate, in future studies we hope to determine if environme...

Brain’s "Default Mode" Awry in Schizophreni

...ents. Schizophrenia is a psychotic disorder that alters patients’ perception, thought processes, and behavior as evidenced by hallucinations, delusions, disorganized speech or behavior, social withdrawal, and varied cognitive deficits. Episodic memory and attention are significantly impaired in schizophre...

Smoking Alters the Human Brain Like Those in Animals Using Illicit Drugs

... research supports the idea that long-term smoking alters the brain in ways that contribute to addiction, and provides insight into how addiction works, says lead author Bruce Hope, PhD, of the National Institute on Drug Abuse (NIDA). The study, supported by NIDA, is published in the issue of The Journal of...

Be Careful What You Touch, It can Make You Fat

...e unborn fetus is exposed to these chemicals. This alters gene functioning in the body, making it do something akin to grabbing every bite it gets and utilizing it. When the offspring enters the world of ample food, the genes overplay, resulting in utilizing every bit of food it ingests, and hence causing...

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