Tag: "agonist" at medical news
New fertility drug development techniques by Organon
...ientists carried out pre-clinical tests of this LH agonist
in rats and found that it induced ovulation after a single oral dose and that fertilization of the ovulated eggs resulted in the normal implantation of healthy embryos in these rats. The scientists at Organon who are also exploring the IVF cycle conc...
Parkinson’s Drug Linked to Gamblin
...ithin one month after their dosage of the dopamine agonist
was increased. All of the patients were in the adv...oblem. Researchers feel higher dosages of dopamine agonist
may be to blame for excessive gambling. They add while the risk of this side effect is small, doctor...
Drug Pramipexole Usage Linked To Gambling Addiction In Parkinsons Patients
...Parkinson’s disease received treatment of dopamine agonist
drug called Pramipexole. The drug manufacturers Boehringer Ingelheim Pharmaceuticals producing Pramipexole (Mirapex) have mentioned the pathologic gambling addiction as a side effect to the use of Pramipexole. Of the 11 patients with links of Pramipe...
Diabetic drug Pioglitazone found to reduce heart risk
...rovascular complications. Pioglitazone is one such agonist
used to treat type-2 diabetes. A recent study, published in the October issue of The Lancet, was conducted to ascertain whether pioglitazone reduces cardiovascular morbidity and mortality in patients with type-2 diabetes, and to assess the safety an...
Aspirin May Protect Against Hyperglycemia With Diabetes
...ence that aspirin improves the calcium response to agonist
and NO production and/or biodisponibility in high concentration glucose condition. The authors assume that the antioxidant properties of aspirin are accountable for these effects, since data show that aspirin may scavenge superoxide anions by reducin...
Mode Of Action Of The Anti-Convulsant Valproate
...eceptor (ER). Bioassays were performed to detect agonist
activity by exposing yeast to CBZ or valproate or ...gonist bioactivity and no significant PR, AR or ER agonist
bioactivity. Valproate also showed a dose-dependent blockade of DHT's suppression of AR-mediated N...
Shaking Legs Syndrome Is Curable
...dications," said Sharma. "Non-ergotamine dopamine agonist
has been found very effective in 80 percent of RLS cases. Benzodiazines and other options are also available." Sharma's advice for relief is to improve sleep schedule and reduce the intake of alcohol and tobacco, besides medication. A cold compress ...
Skin Patch Offers Relief to Patients with Parkinson's disease
...t is a new and simple way of delivering a dopamine agonist
which helps to overcome the problems associated with oral administration. <br...
Breathing Exercises Scores Over Inhalers
... reduction and a 50% decrease in the use of beta-2 agonist
reliever and inhaled corticosteroids respectively were found. And it was found to have significant effects on quality of life, lung function, or constriction of the airways in response to asthma triggers....
Functional Differences In Estrogen Receptor Could Be A Therapeutic Target
...rt the conclusion that tamoxifen functions as both agonist
and antagonist of estrogen signaling and that the expression of hER-a36 may be involved in the development of tamoxifen-resistant human breast cancer. This raises the possibility that estrogen-activated ER-a36 signaling initiated in the cell plasma m...
Prostate Cancer Treatment Increases Risk of Diabetes and Heart Disease
...ections of a gonadotropin-releasing hormone (GnRH) agonist
drug. GnRH agonists are the main therapy for metas...local or regional prostate cancer receiving a GnRH agonist
had a 44 percent higher risk of developing diabetes and a 16 percent higher risk of developing coron...
Swelling of Prostate Gland Prevented with New drug
... developing. On testing an estrogen receptor-beta agonist
on transgenic mice with BPH Risbridger and her team found that the drug activated just one of the two cell receptors for the hormone to produce the positive impact. This was presented at the Society for Endocrinology conference. The scientists found...
Medications for Restless Legs Syndrome may Trigger Compulsive Gambling
...ly for signs of compulsive behaviors once dopamine agonist
treatment has begun. The report suggests that the ...eported this disorder as a side effect of dopamine agonist
therapy in 11 Parkinson disease patients. “Although pathologic gambling has already been recognized ...
New Therapy for Lipid Disorder Demonstrates Varied Results
...to examine the safety and efficacy of a PPAR-alpha agonist
known as LY518674. In one study, 309 patients with atherogenic dyslipidemia (elevated triglycerides and low HDL-C) received LY518674 (in one of 4 doses, 10, 25, 50 or 100 micrograms), placebo, or the fibrate drug fenofibrate. In the other study, 304 ...
Combo Therapy may Be Highly Beneficial in Asthma Control
...ICS), and formoterol, a rapid and long-acting beta agonist
(LABA). As part of the 12-week, randomised, double-blind, placebo-controlled, multicenter study, researchers measured HRQL in 553 patients with moderate-to-severe persistent asthma treated with one of five SYMBICORT therapies. The patients were s...
A Fresh Alternative to Painful Chemotherapy Developed in UK
...hormone that encourages some tumours to grow. An agonist
achieves a normal action, often mimicking the acti... sex hormones in both men and women. Thus, an LHRH agonist
serves in a manner similar to LHRH to control the same sex hormones. Four London centres found tha...
FDA Approves INTUNIV (guanfacine) for the Treatment of ADHD
... and frustration tolerance. The selective alpha-2A agonist
strengthens working memory and prefrontal cortex neuronal firing. This research supports the use of guanfacine for the treatment of ADHD....