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Tag: "adjuvant" at medical news

Combination of Tratuzumab and Chemotherapy Yields Better Results for Breast Cancer

...distant recurrence of breast cancer in women given adjuvant chemotherapy alone or chemotherapy plus trastuzuma...t meta-analysis of current published trials on the adjuvant use of trastuzumab. The results are of great clinical value since they indicate that treatment with ...

Study Confirms Benefits of Chemo, Trastuzumab Combo to Battle Breast Cancer

...distant recurrence of breast cancer in women given adjuvant chemotherapy alone or chemotherapy plus trastuzumab, after breast surgery. Up to a quarter of all breast cancers express large amounts of the HER2 protein or carry multiple copies of the HER2 gene. Those cancers tend to be associated with aggressiv...

Cost-effective Treatments for Breast Cancer

New adjuvant treatments for breast cancer are cost-effective at...ctiveness of different drugs for the management of adjuvant therapies for early breast cancer. In a Canadian economic study of estrogen receptor positive brea...

New Adjuvant Breast Cancer Treatments Found Cost-effective

Two new studies have found that new adjuvant treatments for breast cancer are cost-effective at...ctiveness of different drugs for the management of adjuvant therapies for early breast cancer. In a Canadian economic study of estrogen receptor positive brea...

Bayer and Onyx Submit Supplemental New Drug Application for Nexavar to Treat Liver Cancer

...company- sponsored Phase 3 study of Nexavar in the adjuvant treatment of HCC following the complete removal of early stage liver cancer. The sNDA submission is based on positive data from the international, Phase 3, placebo-controlled Sorafenib HCC Assessment Randomized Protocol (SHARP) trial which demonstra...

DelSite Working Toward Solving Delivery of Influenza Vaccine in Pandemic Situations

...he body: the respiratory tract. 3. An effective adjuvant to make the vaccine more powerful. One proposed ap...proach was to have the vaccine in one vial and the adjuvant in another vial, and then combine the vaccine with the adjuvant at the site of vaccination. It was s...

Breast Cancer Patients Follow-up Devalued

...s would enable patient access to new and expensive adjuvant drugs (such as aromatase inhibitors). It will also...sed on to patients through greater access to novel adjuvant cancer drugs. "This study shows that deciding when and how to discharge patients is a complex matt...

Breast Cancer on Rise Across Middle East

...eatments are safe and effective. For many years, adjuvant Tamoxifen has been the gold standard for endocrine...ifen in advanced disease, neoadjuvant therapy, and adjuvant therapy. "Endocrine therapy, such as Letrozole, remains a very powerful approach to treating breas...

Cell Genesys Reports Additional Data From Phase 2 Clinical Trial of GVAX Immunotherapy for Pancreatic Cancer

...d GVAX after surgical resection of their tumor and adjuvant radiation and chemotherapy. The median overall sur... patients undergoing pancreatic cancer surgery and adjuvant therapy. Of note, 53 of the 60 patients were considered high risk, based on the unfavorable finding ...

Cisplatin-very Effective Than Carboplatin in Nonsmall Cell Lung Cancer Treatment

...n, particularly in the face of new developments in adjuvant chemotherapy for NSCLC patients. The apparent superiority of cisplatin over carboplatin demonstrated in this paper should not be taken lightly, particularly in patients being treated with curative intent. Equally inadvisable would be the use of cis...

Social Factors Not Genetics Drive Racial Disparities in Colorectal Cancer Survival

...ion of screening tests, lower rates of surgery and adjuvant chemotherapy, more aggressive tumors, and poor post-treatment surveillance contribute to lower survival rates. However, the fundamental causes of these associations, including the importance of biologic versus socioeconomic factors, remain poorly cha...

Breast Cancer Vaccine Stimulates Potent Immune Response to Cancer Cells

...chieve this success only by using a bacterial-like adjuvant administered with the right peptide," she said. In addition, Dr. Nava-Parada said that other studies fail to accurately represent human cancers because they measure acute rejection of a tumor cell line that is produced in the laboratory and then in...

Novartis Gleevec Found Effective in Treating Gastro-intestinal Tumors

...mission to gain regulatory approval for Gleevec as adjuvant treatment for GIST." Adjuvant therapy is treatment given in addition to the primary therapy to kill any cancer cells that may have spread, even if the spread cannot be detected by radiologic or laboratory tests. GPL/V...

Combining Therapies can Improve Survival for Early-stage Breast Cancer Patients

...ity of archived tumor specimens for all randomized adjuvant trials. The era in which such large important trials should be carried out without the archived correlational tumor samples is over." Source-Eurekalert ME/B...

Breast Cancer? ER Positive or Negative

...gested that older women are less likely to receive adjuvant therapy for breast cancer. Because older women are...as not seen during this study period. For example, adjuvant use of Herceptin (trastuzumab) was approved in November 2006 for HER-2+ breast cancer (many ER-negat...

'Triple Negative' Breast Cancers Seem to Affect the Young, Minority

... these markers are useful in selecting appropriate adjuvant therapy and prognosis. Around 15 percent of breast...sociated with poor prognosis and survival, hormone adjuvant therapy failure, and are often identified in African American women, little is understood about othe...

Brazilian Boost for Bird Flu Vaccines

...stitute, based in S?o Paulo, Brazil, claim that an adjuvant called Monophosphoryl Lipid A (MPLA) was effective...amese and Indonesian avian flu virus in mice. An adjuvant is a chemical substance that boosts a vaccine's effectiveness by increasing its ability to stimulate...

Early Switch to an Aromatase Inhibitor Increases Survival

...r over the last two decades. The drugs are used as adjuvant to primary surgical treatment for a period of five years. Tamoxifen was the first estrogen modulator shown to increase survival and reduce the risk of breast cancer recurrence. However, tamoxifen is associated with increased risk of death from oth...

Growth Factors Given With Chemotherapy may Increase Risk of Blood Diseases

...at the elevated risk of AML or MDS associated with adjuvant chemotherapy may be further increased by the concu... recent years. They also note that the benefits of adjuvant chemotherapy for breast cancer may far outweigh any risk of a second cancer. "In clinical practice, ...

Oral Flu Vaccine On The Horizon In Russia

...oped an intranasal influenza vaccine using a novel adjuvant technology, with plans to develop what could becom...uMist, which is already on sale in the USA. The adjuvant used in the vaccine, called Korauban, is an immunostimulant gamma interferon inductor that is closel...

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